Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Maria A. Martinez-Martinez"'
Autor:
Julia Beveridge, Eric Tran, Girdhar Singh Deora, Fei Huang, Yuzhi Wang, Kieran Stockton, Ignacio Cotillo, Maria Santos Martinez Martinez, Silvia Gonzalez, Pablo Castañeda, Julian Sherman, Ana Rodriguez, Albane Kessler, Jonathan B. Baell
Publikováno v:
Journal of Medicinal Chemistry. 66:1522-1542
Publikováno v:
Revista de Economía del Caribe.
Esta investigación tiene como objetivo central determinar la existencia de integración espacial entre los mercados de leche cruda del departamento del Atlántico, con los departamentos de Antioquia y Cundinamarca. Para ello, se examinó el precio p
Autor:
Dana M. Klug, Nelly El-Sakkary, Cristina Bosch-Navarrete, Rosario Diaz-Gonzalez, Gloria Ceballos-Pérez, Guiomar Pérez-Moreno, Jeremiah D. Momper, Carlos Cordon-Obras, Francisco Gamarro, Dolores Gonzalez Pacanowska, Maria Santos Martinez-Martinez, Lori Ferrins, Conor R. Caffrey, Eftychia M. Mavrogiannaki, Katherine C. Forbes, Raquel García-Hernández, Claudia Gómez-Liñán, Miguel Navarro, Andreu Saura, Luis M. Ruiz-Pérez, Pilar Manzano, Ali Syed, Lisseth Silva, Michael P. Pollastri
Publikováno v:
J Med Chem
Neglected tropical diseases such as human African trypanosomiasis (HAT) are prevalent primarily in tropical climates and among populations living in poverty. Historically, the lack of economic incentive to develop new treatments for these diseases ha
Autor:
Henok Asfaw, Katja Laqua, Anna Maria Walkowska, Fraser Cunningham, Maria Santos Martinez-Martinez, Juan Carlos Cuevas-Zurita, Lluís Ballell-Pages, Peter Imming
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176088 (2017)
Wollamide B is a cationic antimycobacterial cyclohexapeptide that exhibits activity against Mycobacterium bovis (M. bovis) (IC50 of 3.1 μM). Aiming to define its structural activity relationship (SAR), optimizing potency and pharmacokinetic properti
Externí odkaz:
https://doaj.org/article/eea2060467404578b60d49862c64ef37
Autor:
Santiago Moragon, Cristina Hernando, Maria Teresa Martinez-Martinez, Marta Tapia, Belen Ortega-Morillo, Ana Lluch, Begoña Bermejo, Juan Miguel Cejalvo
Publikováno v:
Cancers. 14(13)
Understanding the biological aspects of immune response in HER2+ breast cancer is crucial to implementing new treatment strategies in these patients. It is well known that anti-HER2 therapy has improved survival in this population, yet a substantial
Autor:
Eusebi Chiner, Nieves B. Navarro-Soriano, Maria A. Martinez-Martinez, Santiago J. Carrizo, Trinidad Díaz-Cambriles, Begoña Gallego, Teresa Gomez-Garcia, Auxiliadora Romero, Francisco J. Vázquez-Polo, Babak Mokhlesi, Maria F. Troncoso, Javier Barca, Cristina Senent, María Luz Alonso-Álvarez, Jesús Sanchez-Gómez, Mónica González, Nicolás González-Mangado, Juan F. Masa, Sergi Marti, Maria Antonia Ramon, M.A. Gómez-Mendieta, Odile Romero, Maria A. Sanchez-Quiroga, Rafael Golpe, Silvia Gómez, Daniel López-Padilla, Miguel Ángel Negrín, Soledad López-Martín, Mercedes Pallero, Jose M. Marin, Estrella Ordax-Carbajo, Carlos Egea, Iván Benítez, Francisco Javier Gómez De Terreros, Jesús Muñoz-Méndez, José N. Sancho-Chust, José M. Benítez, Candela Caballero-Eraso, Jaime Corral, Mónica Bengoa, Elena Ojeda-Castillejo, Emilia Barrot, Ferran Barbé, Eva Arias, Juan Antonio Riesco, María Martel-Escobar
Publikováno v:
Chest. 158:1176-1186
Background Noninvasive ventilation (NIV) is an effective form of treatment in obesity hypoventilation syndrome (OHS) with severe OSA. However, there is paucity of evidence in patients with OHS without severe OSA phenotype. Research Question Is NIV ef
Autor:
Pilar Manzano, Maria Santos Martinez-Martinez, Miguel Navarro, Michael P. Pollastri, Naresh Gunaganti, Gloria Ceballos-Pérez, Kirsten Gillingwater, Domingo I. Rojas-Barros, Rosario Diaz-Gonzalez, Baljinder Singh
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
J Med Chem
instname
J Med Chem
Human African trypanosomiasis (HAT), or sleeping sickness, is caused by the protozoan parasite Trypanosoma brucei and transmitted through the bite of infected tsetse flies. The disease is considered fatal if left untreated. To identify new chemotypes
Autor:
Pradipsinh K. Rathod, Margaret A. Phillips, Michael J. Palmer, Sreekanth Kokkonda, Farah El Mazouni, John H. White, David Waterson, Iñigo Angulo-Barturen, María Belén Jiménez-Díaz, Maria Santos Martinez-Martinez, Helena Barker, Leticia Huertas-Valentin, Jenna McLaren, Santiago Ferrer, Jeremy N. Burrows, Shatrughan P Shahi, Karen L. White, Maria Jose Lafuente-Monasterio, Dave Matthews, Gong Chen, Francis C. K. Chiu, David M. Shackleford, Elly Crighton, Kasiram Katneni, Xiaoyi Deng, Sergio Wittlin, Diana R. Tomchick, Susan A. Charman, Rajesh Chittimalla
Publikováno v:
J Med Chem
Malaria puts at risk nearly half the world's population and causes high mortality in sub-Saharan Africa, while drug resistance threatens current therapies. The pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH) is a validated target
Autor:
Paco de Dios-Anton, Chun-wa Chung, Elena Jimenez, Maria Santos Martinez-Martinez, Fraser Cunningham, Mythily Vimal, Ana Guardia, Raquel Fernandez-Menendez, Arancha Pérez, Jaime Escribano, Jorge Esquivias, Robert H. Bates, María José Rebollo-López, Verónica Sousa-Morcuende, Monica Cacho, Joaquín Rullas, Eva Maria Lopez-Roman, Cristina Rivero, Margaret Neu, Leticia Huertas Valentín
Publikováno v:
ACS Infectious Diseases. 6:1098-1109
In the course of optimizing a novel indazole sulfonamide series that inhibits β-ketoacyl-ACP synthase (KasA) of Mycobacterium tuberculosis, a mutagenic aniline metabolite was identified. Further lead optimization efforts were therefore dedicated to
Autor:
Juan F. Masa, Babak Mokhlesi, Iván Benítez, Maria Victoria Mogollon, Francisco Javier Gomez de Terreros, Maria Ángeles Sánchez-Quiroga, Auxiliadora Romero, Candela Caballero-Eraso, Maria Luz Alonso-Álvarez, Estrella Ordax-Carbajo, Teresa Gomez-Garcia, Mónica González, Soledad López-Martín, José M. Marin, Sergi Martí, Trinidad Díaz-Cambriles, Eusebi Chiner, Carlos Egea, Javier Barca, Francisco-José Vázquez-Polo, Miguel A. Negrín, María Martel-Escobar, Ferran Barbe, Jaime Corral, Agustin Sojo, Nicolás González-Mangado, Maria F. Troncoso, Maria-Ángeles Martinez-Martinez, Elena Ojeda-Castillejo, Daniel López Padilla, Santiago J. Carrizo, Begoña Gallego, Mercedes Pallero, Odile Romero, Maria Antonia Ramón, Eva Arias, Jesús Muñoz-Méndez, Cristina Senent, Jose N. Sancho-Chust, Nieves Belén Navarro Soriano, Emilia Barrot, José M. Benítez, Jesús Sanchez-Gómez, Rafael Golpe, María Antonia Gómez Mendieta, Silvia Gomez, Mónica Bengoa
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Spanish Sleep Network.
[Rationale] Obesity hypoventilation syndrome (OHS) has been associated with cardiac dysfunction. However, randomized trials assessing the impact of long-term noninvasive ventilation (NIV) or continuous positive airway pres
[Rationale] Obesity hypoventilation syndrome (OHS) has been associated with cardiac dysfunction. However, randomized trials assessing the impact of long-term noninvasive ventilation (NIV) or continuous positive airway pres