Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Maria A. Ermolaeva"'
Autor:
Huahui Li, Yuting Li, Ying Zhang, Binbin Tan, Tuxiong Huang, Jixian Xiong, Xiangyu Tan, Maria A. Ermolaeva, Li Fu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Hepatocellular carcinoma (HCC) remains a devastating malignancy worldwide due to lack of effective therapy. The immune-rich contexture of HCC tumor microenvironment (TME) makes this tumor an appealing target for immune-based therapies; however, the i
Externí odkaz:
https://doaj.org/article/15f98c35a82d49918678941aea7bd3f5
Autor:
Vanesa Fernández-Majada, Patrick-Simon Welz, Maria A. Ermolaeva, Michael Schell, Alexander Adam, Felix Dietlein, David Komander, Reinhard Büttner, Roman K. Thomas, Björn Schumacher, Manolis Pasparakis
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
CYLD is a deubiquitinase known to act as a tumour suppressor in different models of carcinogenesis. Here, the authors show that CYLD suppresses carcinogen-induced tumorigenesis by deubiquitinating p53 and promoting its stabilization and activation in
Externí odkaz:
https://doaj.org/article/79bd90df0bdb446e800325e92d9eaee1
Publikováno v:
Mir psikhologii. :170-179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b14043edfb617aeb75dbfe5f58c8504
https://doi.org/10.51944/2073-8528_2021_4_170
https://doi.org/10.51944/2073-8528_2021_4_170
Autor:
Christiane Frahm, Madlen Guenther, Maria A. Ermolaeva, Emanuel Barth, Otto W. Witte, Akash Srivastava, Manja Marz
Publikováno v:
Genomics, Proteomics & Bioinformatics
Aging is a complex process that can be characterized by functional and cognitive decline in an individual. Aging can be assessed based on the functional capacity of vital organs and their intricate interactions with one another. Thus, the nature of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bdfa6082deab8e4884dea9c79ea6ff
http://europepmc.org/articles/PMC8242333
http://europepmc.org/articles/PMC8242333
Autor:
Luba A. Astakhova, Artem D. Novoselov, Maria E. Ermolaeva, Michael L. Firsov, Alexander Yu. Rotov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13400, p 13400 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13400
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13400
International Journal of Molecular Sciences
Green rods (GRs) represent a unique type of photoreceptor to be found in the retinas of anuran amphibians. These cells harbor a cone-specific blue-sensitive visual pigment but exhibit morphology of the outer segment typical for classic red rods (RRs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ecf11d993f2ffc70eb75214113a3e8
https://www.mdpi.com/1422-0067/22/24/13400
https://www.mdpi.com/1422-0067/22/24/13400
Publikováno v:
Ageing Research Reviews. 23:3-11
The maintenance of the genome is of pivotal importance for the functional integrity of cells and tissues. The gradual accumulation of DNA damage is thought to contribute to the functional decline of tissues and organs with ageing. Defects in multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb0815395f343ac5d9c2ada976bc827
https://doi.org/10.1016/j.arr.2014.12.009
https://doi.org/10.1016/j.arr.2014.12.009
Autor:
Peter Frommolt, Maria A. Ermolaeva, Jennifer I. Schneider, Bernhard Schermer, Michael M. Mueller, Sebastian Greiss, Laia Castells-Roca, Roman-Ulrich Müller, Vipin Babu, Björn Schumacher, Ashley B. Williams, Thomas Benzing
Publikováno v:
Nature cell biology
Mueller, M M, Castells-Roca, L, Babu, V, Ermolaeva, M A, Mueller, R-U, Frommolt, P, Williams, A B, Greiss, S, Schneider, J I, Benzing, T, Schermer, B & Schumacher, B 2014, ' DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage ', Nature Cell Biology, vol. 16, no. 12, pp. 1168–1179 . https://doi.org/10.1038/ncb3071
Mueller, M M, Castells-Roca, L, Babu, V, Ermolaeva, M A, Mueller, R-U, Frommolt, P, Williams, A B, Greiss, S, Schneider, J I, Benzing, T, Schermer, B & Schumacher, B 2014, ' DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage ', Nature Cell Biology, vol. 16, no. 12, pp. 1168–1179 . https://doi.org/10.1038/ncb3071
Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility and premature ageing. It remains poorly understood how DNA damage responses function during organismal development and maintain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58af1758a5b2b8bfde585cbe44bc71b7
http://europepmc.org/articles/PMC4250074
http://europepmc.org/articles/PMC4250074
Autor:
Maria A. Ermolaeva, Björn Schumacher
Publikováno v:
Trends in Genetics
DNA damage checkpoints are important tumor-suppressor mechanisms that halt cell cycle progression to allow time for DNA repair, or induce senescence and apoptosis to remove damaged cells permanently. Non-cell-autonomous DNA damage responses activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046d964da3bd89fe5afe9c1c19d64a15
https://doi.org/10.1016/j.tig.2013.12.001
https://doi.org/10.1016/j.tig.2013.12.001
Autor:
Jaclyn M Fingerhut, Jayshree Khanikar, Björn Schumacher, Stefanie Wolters, Raymond C. Chan, Maria A. Ermolaeva, Jeremy S. Bickel
Publikováno v:
Genetics
DNA damage by ultraviolet (UV) light poses a risk for mutagenesis and a potential hindrance for cell cycle progression. Cells cope with UV-induced DNA damage through two general strategies to repair the damaged nucleotides and to promote cell cycle p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f114df0a1919605d6a260afa9e2c6f
http://europepmc.org/articles/PMC3982690
http://europepmc.org/articles/PMC3982690
Autor:
Geert van Loo, Vanesa Fernández-Majada, Vangelis Kondylis, Andy Wullaert, Maria A. Ermolaeva, Manolis Pasparakis, Petra Kirsch, Patrick-Simon Welz, Anja Sterner-Kock, Katerina Vlantis
Publikováno v:
Nature; Vol 477
Nature
Nature
Intestinal immune homeostasis depends on a tightly regulated cross talk between commensal bacteria, mucosal immune cells and intestinal epithelial cells (IECs). Epithelial barrier disruption is considered to be a potential cause of inflammatory bowel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60151d8e34dcf5cbd15bc471686ab6ca