Divergent Entry to C-Glycosides from Unprotected Sugars

Autor: Lisheng Mao, Francisco Alvarez, Sébastien Dropsit-Montovert, Long Lu, Maria Dalko-Csiba, Xavier Marat, Jinzhu Xu, Yudi Ding, Susana Ramos, Amélie Prévot-Guéguiniat, Florence Pic, Clément Aracil, Magali Lima, Marie-Céline Frantz

Publikováno v: Organic Letters. 21:2684-2687

An efficient, divergent, and straightforward access to novel C-glycosides has been developed, namely, α-hydroxy carboxamide and carboxylic acid derivatives, via a green and scalable process from unprotected carbohydrates. The method involves condens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7c751696a7a4b5c5aacf5f25f11d41
https://doi.org/10.1021/acs.orglett.9b00666

Fragment pharmacophore-based in silico screening: a powerful approach for efficient lead discovery

Autor: Laurence Deyon-Jung, Christophe Morice, Florence Chéry, Julie Gay, Thierry Langer, Marie-Céline Frantz, Roger Rozot, Maria Dalko-Csiba

Publikováno v: MedChemComm. 7:506-511

Through a process of fragmentation, functionalization, and recombination of market approved molecules for cosmetic usage, we customized an in-house virtual library comprising molecules ideally suited for virtual screening. Computational pharmacophore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32b93fc984ce7e311fd7ba53334b76b6
https://doi.org/10.1039/c5md00444f

A jasmonic acid derivative improves skin healing and induces changes in proteoglycan expression and glycosaminoglycan structure

Autor: Sibylle Jäger, Christian Tran, Maria Dalko-Csiba, Anne-Marie Minondo, Jean-François Michelet, Florian Formanek, Philippe Bastien, Hugues Lortat-Jacob, Elodie Henriet, Lionel Breton, Romain R. Vivès

Publikováno v: Biochimica et Biophysica Acta (BBA)-General Subjects
Biochimica et Biophysica Acta (BBA)-General Subjects, Elsevier, 2017, 1861 (9), pp.2250-2260. ⟨10.1016/j.bbagen.2017.06.006⟩
Biochimica et Biophysica Acta (BBA)-General Subjects, 2017, 1861 (9), pp.2250-2260. ⟨10.1016/j.bbagen.2017.06.006⟩

Background Jasmonates are plant hormones that exhibit anti-cancer and anti-inflammatory properties and have therefore raised interest for human health applications. The molecular basis of these activities remains poorly understood, although increasin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6801740c77589f5bebec0c67b0f94539
https://hal.archives-ouvertes.fr/hal-01553681

L'Oreal's comment on P. Anastas article 'The UN Sustainability Goals: How can Sustainable Chemistry Contribute'

Autor: Maria Dalko-Csiba, Michel Philippe, Jinzhu Xu, Maude Brossat, Anne-Claude Dublanchet, Julien Hitce, Marie-Céline Frantz

Publikováno v: Current Opinion in Green and Sustainable Chemistry. 13:171

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9f27e105b5dfe4d7f875feb136a503e
https://doi.org/10.1016/j.cogsc.2018.09.007

Synthesis of Pro-XylaneTM: A new biologically active C-glycoside in aqueous media

Autor: Christophe Boulle, Alexandre Cavezza, Amelie Gueguiniat, Patrick Pichaud, Louis Ricard, Simon Trouille, Maria Dalko-Csiba

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 19:845-849

The scope and limitation of Lubineau's reaction were evaluated for the synthesis of C-glycosides (compounds 1-13). Further transformation of side chain carbonyl was also achieved (compounds 16-23). Optimization of these two steps was investigated in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058ce972098bb624144a64b7d8096a71
https://doi.org/10.1016/j.bmcl.2008.12.037