Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Maria A. Bausero"'
Autor:
Bertil G. Ohlsson, Björn Carlsson, Mikael C.O. Englund, Olov Wiklund, Lena M. S. Carlsson, Margareta Jernås, Maria A. Bausero, Per-Arne Svensson, Alexzander Asea
Publikováno v:
Atherosclerosis. 185:32-38
Lipid accumulation and inflammation are key hallmarks of the atherosclerotic plaque and macrophage uptake of oxidized low-density lipoprotein (oxLDL) is believed to drive these processes. Initial experiments show that supernatants from oxLDL treated
Autor:
Christian Jantschitsch, Alexzander Asea, Ajit Bharti, Daniel R. Ciocca, Susana L. Ordonez, Maria A. Bausero, Diana T. Page, Kristen D. Perez, Jason W.-L. Eng, Edwina E. Asea, Ingela Kindas-Muegge
Publikováno v:
Tumor Biology. 27:17-26
The 25-kDa heat shock protein (Hsp25) is associated with various malignancies and is expressed at high levels in biopsies as well as circulating in the serum of breast cancer patients. In this study, we used RNA interference technology to silence the
Publikováno v:
The Journal of Immunology. 175:2900-2912
IFN-γ exhibits differential effects depending on the target and can induce cellular activation and enhance survival or mediate cell death via activation of apoptotic pathways. In this study, we demonstrate an alternative mechanism by which IFN-γ en
Autor:
Gabriele Multhoff, Josef A. Schroeder, Alexzander Asea, Catharina C. Gross, Maria A. Bausero, Mathias Gehrmann, Robert Gastpar
Publikováno v:
Cancer Research. 65:5238-5247
Detergent-soluble membrane vesicles are actively released by human pancreas (Colo−/Colo+) and colon (CX−/CX+) carcinoma sublines, differing in their capacity to present heat shock protein 70 (Hsp70)/Bag-4 on their plasma membranes. Floating prope
Autor:
Alexzander Asea, Elizabeth Palaima, Maegan A McCormick, Thomas T. Perls, Stacy L. Andersen, Dellara F. Terry, Emily A. Schoenhofen, Kishiko Ogawa, Maria A. Bausero, JaeMi Pennington
Publikováno v:
Annals of the New York Academy of Sciences. 1019:502-505
Cardiovascular disease is a major cause of morbidity and mortality of older Americans. We have demonstrated recently that centenarian offspring, when compared with age-matched controls, avoid and/or delay cardiovascular disease and cardiovascular ris
Publikováno v:
Tumor Biology. 25:243-251
The expression of unique surface structures on tumors that allow for recognition and activation of host immunocompetent cells plays an important role in determining tumor growth and/or metastasis. Recent studies have identified an important role for
Autor:
Maria A. Bausero, Elizabeth Palaima, Lillian McMahon, Elizabeth S. Klings, Adeboye H. Adewoye, Safaya Surinder, Martin H. Steinberg, Mark Yoder, Alexzander Asea, Harrison W. Farber, Adam Odhiambo
Publikováno v:
American Journal of Hematology. 78:240-242
Inflammation may play an important role in the pathophysiology of sickle cell disease (SCD), and recent studies have identified the 70-kDa heat shock protein (Hsp70) as an important mediator of inflammatory responses. Here we demonstrate a significan
Autor:
Edwina E. Asea, Ganachari M. Nagaraja, Punit Kaur, Alexzander Asea, William Neumann, Maria A. Bausero, Gabriele Multhoff
Publikováno v:
Cancer Prev. Res. 5, 122-137 (2012)
Relatively high expression of Hsp27 in breast and prostate cancer is a predictor of poor clinical outcome. This study elucidates a hitherto unknown mechanism by which Hsp27 regulates proteasome function and modulates tumor-specific T-cell responses.
Autor:
Punit Kaur, Maria A. Bausero, Ganachari M. Nagaraja, Mark D. Hurwitz, Alexzander Asea, Judith Manola
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 95(3)
Hsp72 found in the extracellular milieu has been shown to play an important role in immune regulation. The impact of common cancer therapies on extracellular release of Hsp72 however, has been to date undefined.Serum from 13 patients undergoing radia
Autor:
Ángela Diblasi, Olga Tello, Francisco E. Gago, Maria A. Bausero, Daniel R. Ciocca, Mariel A. Fanelli, Eduardo Callegari, Magdalena Montt-Guevara, F. Darío Cuello-Carrión
Publikováno v:
Cell stresschaperones. 13(2)
The cadherin-catenin proteins have in common with heat shock proteins (HSP) the capacity to bind/interact proteins of other classes. Moreover, there are common molecular pathways that connect the HSP response and the cadherin-catenin protein system.