Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Maria A Tikhonova"'
Autor:
Meng Chang Ko, Min Chong Lee, Tamara G Amstislavskaya, Maria A Tikhonova, Yi-Ling Yang, Kwok-Tung Lu
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e106692 (2014)
The loop diuretic bumetanide (Bumex) is thought to have antiepileptic properties via modulate GABAA mediated signaling through their antagonism of cation-chloride cotransporters. Given that loop diuretics may act as antiepileptic drugs that modulate
Externí odkaz:
https://doaj.org/article/1246ccb35b7b4c53a556891293e8954b
Autor:
Alexander B. Pupyshev, Anna A. Akopyan, Michael V. Tenditnik, Marina V. Ovsyukova, Nina I. Dubrovina, Victor M. Belichenko, Tatiana A. Korolenko, Svetlana A. Zozulya, Tatiana P. Klyushnik, Maria A. Tikhonova
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 813 (2024)
In the treatment of experimental neurodegeneration with disaccharide trehalose, various regimens are used, predominantly a 2% solution, drunk for several weeks. We studied the effects of different regimens of dietary trehalose treatment in an amyloid
Externí odkaz:
https://doaj.org/article/35c4efef3f3d44fa9ae20d255f1ef955
Autor:
Elena A. Filimonova, Anton A. Pashkov, Galina I. Moysak, Anastasia Y. Tropynina, Svetlana Y. Zhanaeva, Anna A. Shvaikovskaya, Anna A. Akopyan, Konstantin V. Danilenko, Lyubomir I. Aftanas, Maria A. Tikhonova, Jamil A. Rzaev
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Mesial temporal lobe epilepsy is the most common type of focal epilepsy, imposing a significant burden on the health care system worldwide. Approximately one-third of patients with this disease who do not adequately respond to pharmacotherapy are con
Externí odkaz:
https://doaj.org/article/ec768bc59f5144f89d8be5a97ff05889
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/eba5a92015474276b8c9db6a94e4b531
Autor:
Alexander B. Pupyshev, Tatyana P. Klyushnik, Anna A. Akopyan, Sandeep Kumar Singh, Maria A. Tikhonova
Publikováno v:
Pharmacological Research, Vol 183, Iss , Pp 106373- (2022)
Induction of autophagy is a prospective approach to the treatment of neurodegeneration. In the recent decade, trehalose attracted special attention. It is an autophagy inducer with negligible adverse effects and is approved for use in humans accordin
Externí odkaz:
https://doaj.org/article/2bb6de8fa85a4b50bdf47ee3af68488c
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/13e10da8e4204309894dd587cff9ef75
Autor:
Irina Rozkova, Eugeny Brusentsev, Tatyana Igonina, Diana Ragaeva, Olga Petrova, Maria A. Tikhonova, Anna A. Akopyan, Tamara G. Amstislavskaya, Yegor V. Antonov, Sergey Amstislavsky
Publikováno v:
Hypertension in Pregnancy, Vol 39, Iss 3, Pp 283-294 (2020)
The study investigates how surgery during pregnancy, i.e., sham operation associated with embryo transfer, affects hypertensive phenotype in ISIAH rats genetically predisposed to hypertension. ISIAH rats born after maternal surgery at fourth day of p
Externí odkaz:
https://doaj.org/article/473d5635dd784eb2ae4e9240b7756151
Autor:
Maria A. Tikhonova, Nikolai A. Maslov, Alim A. Bashirzade, Eugenyi V. Nehoroshev, Vladislav Y. Babchenko, Nadezhda D. Chizhova, Elena O. Tsibulskaya, Anna A. Akopyan, Evgeniya V. Markova, Yi-Ling Yang, Kwok-Tung Lu, Allan V. Kalueff, Lyubomir I. Aftanas, Tamara G. Amstislavskaya
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1751 (2022)
Traumatic brain injury (TBI) is a major public health problem. Here, we developed a novel model of non-invasive TBI induced by laser irradiation in the telencephalon of adult zebrafish (Danio rerio) and assessed their behavior and neuromorphology to
Externí odkaz:
https://doaj.org/article/a48dd680c59b4ffd8182967d32ab76e7
Autor:
Maria A. Tikhonova, Tamara G. Amstislavskaya, Victor M. Belichenko, Larisa A. Fedoseeva, Sergey P. Kovalenko, Ekaterina E. Pisareva, Alla S. Avdeeva, Nataliya G. Kolosova, Nikolai D. Belyaev, Lyubomir I. Aftanas
Publikováno v:
BMC Neuroscience, Vol 19, Iss S1, Pp 15-28 (2018)
Abstract Background The dominant hypothesis about the pathogenesis of Alzheimer’s disease (AD) is the “amyloid cascade” concept and modulating the expression of proteins involved in the metabolism of amyloid-beta (Aβ) is proposed as an effecti
Externí odkaz:
https://doaj.org/article/e36633a412f3407296603b97987811c4
Autor:
Shih-Te Yang, Hsiu-Yi Hung, Long-Sun Ro, Ming-Feng Liao, Tamara G. Amstislavskaya, Maria A. Tikhonova, Yi-Ling Yang, Kwok-Tung Lu
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2169 (2021)
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity among the global youth and commonly results in long-lasting sequelae, including paralysis, epilepsy, and a host of mental disorders such as major depressive disorder. Previous
Externí odkaz:
https://doaj.org/article/73cb9c9990bb4c148f9cff83f296f434