Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Maria A Curotto de Lafaille"'
Autor:
Jin-Shu He, Sharrada Subramaniam, Vipin Narang, Kandhadayar Srinivasan, Sean P. Saunders, Daniel Carbajo, Tsao Wen-Shan, Nur Hidayah Hamadee, Josephine Lum, Andrea Lee, Jinmiao Chen, Michael Poidinger, Francesca Zolezzi, Juan J. Lafaille, Maria A. Curotto de Lafaille
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
IgE is an important mediator of protective immunity as well as allergic reaction, but how high affinity IgE antibodies are produced in memory responses is not clear. Here the authors show that IgE can be generated via class-switch recombination in Ig
Externí odkaz:
https://doaj.org/article/b0cb1457667e4bd2866daf4adcb12580
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The long-term effectiveness of antibody responses relies on the development of humoral immune memory. Humoral immunity is maintained by long-lived plasma cells that secrete antigen-specific antibodies, and memory B cells that rapidly respond to antig
Externí odkaz:
https://doaj.org/article/84d322c9d5774a54a0246a1ca2b615d2
Autor:
Miyo Ota, Kenneth B. Hoehn, Takayuki Ota, Carlos J. Aranda, Sara Friedman, Weslley F. Braga, Alefiyah Malbari, Steven H. Kleinstein, Scott H. Sicherer, Maria A. Curotto de Lafaille
Publikováno v:
bioRxiv
Food allergy is caused by allergen-specific IgE antibodies but little is known about the B cell memory of persistent IgE responses. Here we describe in human pediatric peanut allergy CD23+IgG1+memory B cells arising in type 2 responses that contain p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593f4f5308c2746ec5b20a966bf36ab3
https://europepmc.org/articles/PMC9900782/
https://europepmc.org/articles/PMC9900782/
Autor:
Michael T. Wong, Jinmiao Chen, Sriram Narayanan, Wenyu Lin, Rosslyn Anicete, Henry Tan Kun Kiaang, Maria Alicia Curotto De Lafaille, Michael Poidinger, Evan W. Newell
Publikováno v:
Cell Reports, Vol 11, Iss 11, Pp 1822-1833 (2015)
Single-cell analysis technologies such as mass cytometry allow for measurements of cellular heterogeneity with unprecedented dimensionality. Here, we applied dimensionality reduction and automated clustering methods on human T helper (TH) cells deriv
Externí odkaz:
https://doaj.org/article/c632625067204208ab819bc23876663c
Autor:
Carlos J. Aranda, Edgar Gonzalez‐Kozlova, Sean P. Saunders, Weslley Fernandes‐Braga, Miyo Ota, Sriram Narayanan, Jin‐Shu He, Ester Del Duca, Bose Swaroop, Sacha Gnjatic, Gail Shattner, Joan Reibman, Nicholas A. Soter, Emma Guttman‐Yassky, Maria A. Curotto de Lafaille
Publikováno v:
AllergyREFERENCES.
Atopic diseases are characterized by IgE antibody responses that are dependent on cognate CD4 T cell help and T cell-produced IL-4 and IL-13. Current models of IgE cell differentiation point to the role of IgG memory B cells as precursors of pathogen
Autor:
Yin-Hu Wang, Lucile Noyer, Sascha Kahlfuss, Dimitrius Raphael, Anthony Y. Tao, Ulrike Kaufmann, Jingjie Zhu, Marisa Mitchell-Flack, Ikjot Sidhu, Fang Zhou, Martin Vaeth, Paul G. Thomas, Sean P. Saunders, Kenneth Stauderman, Maria A. Curotto de Lafaille, Stefan Feske
Publikováno v:
Science Advances. 8
T cell activation and function depend on Ca2+signals mediated by store-operated Ca2+entry (SOCE) through Ca2+release–activated Ca2+(CRAC) channels formed by ORAI1 proteins. We here investigated how SOCE controls T cell function in pulmonary inflamm
Autor:
Jin-Shu He, Sharrada Subramaniam, Vipin Narang, Kandhadayar Srinivasan, Sean P. Saunders, Daniel Carbajo, Tsao Wen-Shan, Nur Hidayah Hamadee, Josephine Lum, Andrea Lee, Jinmiao Chen, Michael Poidinger, Francesca Zolezzi, Juan J. Lafaille, Maria A. Curotto de Lafaille
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The originally published version of this Article contained errors in Fig. 4 that were introduced during the production process. In panel c, the two uppermost labels ‘IgE spleen’ and ‘IgE BM’ incorrectly read ‘IgG1 spleen’ and ‘IgE1 BM
Externí odkaz:
https://doaj.org/article/c034e958099243d49d5167842016b4be
Autor:
Ephraim Kenigsberg, Joan Shang, Jovani Catalan, Tamar Plitt, Dan Fu Ruan, Katherine E. Lindblad, Jamie Redes, Francesca Cossarini, Zeynep H. Gümüş, Maria Casanova-Acebes, Julio A. Aguirre-Ghiso, Nina Bhardwaj, Robert M. Samstein, Venu Pothula, Uri Laserson, Matthew Lin, Erica Dalla, Jeremiah J. Faith, Manasi Agrawal, Alice O. Kamphorst, Ivan Reyes Torres, Luisanna Pia, Monica Centa, Jessica Tan, Brian D. Brown, Jonathan Chung, Graham J. Britton, Miriam Saffern, Assaf Magen, Matthew P. Spindler, Conor Gruber, Saurabh Mehandru, Amir Horowitz, Timothy O'Donnell, Florian Krammer, Jill Gregory, Gabrielle Lubitz, Pauline Hamon, Meriem Belabed, Matthew Brown, Emma Risson, Louise Malle, Emilie K. Grasset, Alfonso R. Sanchez-Paulete, Justine Noel, Zafar Mahmood, Daniel Lozano-Ojalvo, Mark P. Roberto, Julia Kodysh, Verena van der Heide, Evan Cody, Elliot Meritt, Chang Moon, Maria Suprun, Andrew Leader, Bérengère Salomé, Nicolas F. Fernandez, Dusan Bogunovic, Michelle Tran, Nicolas Vabret, Dirk Homann, Miyo Ota, Cansu Cimen Bozkus, Andrew Charap, Divya Jha, Konstantina Alexandropoulos, Etienne Humblin, Benjamin Greenbaum, Maria Kuksin, Gustavo Martinez-Delgado, Andrew K Chan, Myvizhi Esai Selvan, C. Matthias Wilk, Maria A. Curotto de Lafaille, Samarth Hegde, Alessandra Soares Schanoski, Joel Kim, Jaime Mateus-Tique, Alvaro Moreira, John A. Grout, Rachel Levantovsky, Natalie Vaninov, Peter S. Heeger, Mark Aleynick, Matthew D. Park, Judy H. Cho, Miriam Merad, Steven T. Chen
Publikováno v:
Immunity
The coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an unprecedented effort from the scientific community to understand the biolo
Autor:
Ewa Rakowski, Nedim Durmus, Maria A. Curotto de Lafaille, Sibo Zhao, Shilpi Ahuja, Mengling Liu, Yinxiang Wu, Gabriele Grunig, Joan Reibman
Publikováno v:
Clinical & Experimental Allergy. 49:163-170
Background Blood eosinophils are used to determine eligibility for agents targeting IL-5 in patients with uncontrolled asthma. However, little is known about the variability of blood eosinophil measures in these patients before treatment initiation.
Publikováno v:
Immunity. 50:285-287
IgE antibodies are essential mediators of allergies. In a recent study in Science, Croote et al. (2018) characterize IgE cells isolated from individuals allergic to peanuts. Their findings provide insight into the differentiation of IgE cells in huma