Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Maria A, Dosil"'
Autor:
Xavier Dolcet, Xavier Matias-Guiu, Antonio Llombart-Cussac, Joan Valls, Maria Santacana, Cristina Mirantes, Maria Alba Dosil, Mónica Domingo, Nuria Eritja
PDF - 762K, Four ECCs (IK, AN3CA, MFE-296 and HEC-1A) were treated with Dovitinib (0.05-0.1-0.5-1-2.5 micromol/L) for 48 and 72 hours, and cell viability was assessed by MTT assay. B) Three ECCs (AN3CA, MFE-296 and HEC-1A) were treated with 0.5 micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205b8057e223687851831dfb6886643f
https://doi.org/10.1158/1535-7163.22500994.v1
https://doi.org/10.1158/1535-7163.22500994.v1
Autor:
Xavier Dolcet, Xavier Matias-Guiu, Antonio Llombart-Cussac, Joan Valls, Maria Santacana, Cristina Mirantes, Maria Alba Dosil, Mónica Domingo, Nuria Eritja
PDF - 86K, Endometrial cancer cell lines were treated with ICI 182,780 at 100nM. Total protein lysates were extracted at indicated times after treatment and were subjected to western blot for the expression of ERalpha. Tubulin is shown as at loading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141541b81db52162c13859753de02060
https://doi.org/10.1158/1535-7163.22500982
https://doi.org/10.1158/1535-7163.22500982
Autor:
Xavier Dolcet, Xavier Matias-Guiu, Antonio Llombart-Cussac, Joan Valls, Maria Santacana, Cristina Mirantes, Maria Alba Dosil, Mónica Domingo, Nuria Eritja
PDF - 3065K, Uteri from mice treated during 15 days with Dovitinib (20mg/kg daily) and/or ICI182.780 (5mg/kg) were extracted. Immunostaining for ERalpha and Cyclin D1 was performed to ensure ICI182.780 treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbe8c7b085558acd3049f8e17b21644
https://doi.org/10.1158/1535-7163.22500979
https://doi.org/10.1158/1535-7163.22500979
Autor:
Xavier Dolcet, Xavier Matias-Guiu, Antonio Llombart-Cussac, Joan Valls, Maria Santacana, Cristina Mirantes, Maria Alba Dosil, Mónica Domingo, Nuria Eritja
PDF - 1218K, Four ECCs (IK, AN3CA, MFE-296 and HEC-1A) were treated with Dovitinib (0.05-0.1-0.5-1-2.5 μmol/L) for 72 hours. Cells were stained with Hoechst. The graph on the right shows the percentage of cells displaying apoptotic nuclei in each co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030f3740c76466623d75c5fc88c8e809
https://doi.org/10.1158/1535-7163.22500991.v1
https://doi.org/10.1158/1535-7163.22500991.v1
Autor:
Xavier Dolcet, Xavier Matias-Guiu, Antonio Llombart-Cussac, Joan Valls, Maria Santacana, Cristina Mirantes, Maria Alba Dosil, Mónica Domingo, Nuria Eritja
PDF - 51K, Analysis of Variance tables. Degrees of freedom (Df), sum of squares (SS), mean sum of squares (Mean SS) and corresponding F statistic and p-value are shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3aed51bcafebaae7f960f162e8a6df
https://doi.org/10.1158/1535-7163.22500970.v1
https://doi.org/10.1158/1535-7163.22500970.v1
Autor:
Xavier Dolcet, Xavier Matias-Guiu, Antonio Llombart-Cussac, Joan Valls, Maria Santacana, Cristina Mirantes, Maria Alba Dosil, Mónica Domingo, Nuria Eritja
Mutations in fibroblast growth factor receptor 2 (FGFR2) have been recently described as a molecular-specific feature in endometrial carcinomas and the presence of activated FGFR2 mutations is associated with poor prognosis. For that reason, inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478f14ae87df1a1e298157b8d794de4f
https://doi.org/10.1158/1535-7163.c.6536650.v1
https://doi.org/10.1158/1535-7163.c.6536650.v1
Autor:
Xavier Dolcet, Xavier Matias-Guiu, Antonio Llombart-Cussac, Joan Valls, Maria Santacana, Cristina Mirantes, Maria Alba Dosil, Mónica Domingo, Nuria Eritja
PDF - 66K, Legends for Supplementary Figures 1 through 5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bb9a13d4f1903e204d5c1bdef4b0e9
https://doi.org/10.1158/1535-7163.22500976.v1
https://doi.org/10.1158/1535-7163.22500976.v1
Autor:
Xavier Dolcet, Xavier Matias-Guiu, Antonio Llombart-Cussac, Joan Valls, Maria Santacana, Cristina Mirantes, Maria Alba Dosil, Mónica Domingo, Nuria Eritja
PDF - 27K, Representative graphs mean of cell survival (in percentages) for each combination of Dovitinib and ICI. Confidence intervals as estimated from the linear models are shown. Experiments were performed, at least, 3 times on 3 independent days
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac12d9031fb360035c67d63e91b207f3
https://doi.org/10.1158/1535-7163.22500985.v1
https://doi.org/10.1158/1535-7163.22500985.v1
Autor:
Cristina Mirantes, Núria Eritja, Maria Alba Dosil, Maria Santacana, Judit Pallares, Sónia Gatius, Laura Bergadà, Oscar Maiques, Xavier Matias-Guiu, Xavier Dolcet
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 3, Pp 710-720 (2013)
SUMMARY PTEN is one of the most frequently mutated tumor suppressor genes in human cancers. The role of PTEN in carcinogenesis has been validated by knockout mouse models. PTEN heterozygous mice develop neoplasms in multiple organs. Unfortunately, th
Externí odkaz:
https://doaj.org/article/ef731cf3c44f4c4d94d4002ea39b22b3
Autor:
Ana Velasco, Marta Vaquero, Cristina Megino, Sonia Gatius, Isidre Felip, Raúl Navaridas, Cristina Mirantes, Xavier Dolcet, Maria Alba Dosil, Carla Barceló, Izaskun Urdanibia, Anna Macià, Jordi Tarragona, Maria Santacana, Xavier Matias-Guiu, Carme Piñol, Nuria Eritja, Mónica Domingo, Oscar Maiques
Publikováno v:
The Journal of Pathology. 247:72-85
Many human cancers present Phosphatase and tensin homolog (PTEN) deficiency and between 20 and 30% of colorectal tumors show PTEN loss. The transcription factor, E2 promoter binding factor 1 (E2F-1), exhibits tumor promoter or suppressive functions d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dfd08d71f8ec5a26ed0e8baeb0058b8
https://doi.org/10.1002/path.5168
https://doi.org/10.1002/path.5168