Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Marián Hajdúch"'
Autor:
Tereza Buchtova, Zdenek Skrott, Katarina Chroma, Jiri Rehulka, Petr Dzubak, Marian Hajduch, David Lukac, Stefanos Arampatzis, Jiri Bartek, Martin Mistrik
Publikováno v:
Molecular Oncology, Vol 16, Iss 7, Pp 1541-1554 (2022)
Disulfiram (DSF), an established alcohol‐aversion drug, is a candidate for repurposing in cancer treatment. DSF’s antitumor activity is supported by preclinical studies, case reports, and small clinical trials; however, ongoing clinical trials of
Externí odkaz:
https://doaj.org/article/3191b1b97405485c86205c2179ad7bf2
Autor:
Amanda Centorame, Daciana Catalina Dumut, Mina Youssef, Martin Ondra, Irenej Kianicka, Juhi Shah, Radu Alexandru Paun, Tomas Ozdian, John W. Hanrahan, Ekaterina Gusev, Basil Petrof, Marian Hajduch, Radu Pislariu, Juan Bautista De Sanctis, Danuta Radzioch
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cystic fibrosis (CF) is the most common autosomal recessive genetic disease in Caucasians, affecting more than 100,000 individuals worldwide. It is caused by pathogenic variants in the gene encoding CFTR, an anion channel at the plasma membrane of ep
Externí odkaz:
https://doaj.org/article/e7cbeba9b2d34e6f99a2512513ff9ddf
Autor:
Zuleima Blanco, Esteban Fernandez-Moreira, Michael R. Mijares, Carmen Celis, Gricelis Martínez, Juan B. De Sanctis, Soňa Gurská, Petr Džubák, Marián Hajdůch, Ali Mijoba, Yael García, Xenón Serrano, Nahum Herrera, Jhonny Correa-Abril, Yonathan Parra, Jorge Ángel, Hegira Ramírez, Jaime E. Charris
Publikováno v:
Molecules, Vol 27, Iss 17, p 5626 (2022)
The coexistence of leishmaniasis, Chagas disease, and neoplasia in endemic areas has been extensively documented. The use of common drugs in the treatment of these pathologies invites us to search for new molecules with these characteristics. In this
Externí odkaz:
https://doaj.org/article/2f9fecb0b6884c4cb8a3b7f2b739e2f1
Autor:
Radu A. Paun, Daciana C. Dumut, Amanda Centorame, Thusanth Thuraisingam, Marian Hajduch, Martin Mistrik, Petr Dzubak, Juan B. De Sanctis, Danuta Radzioch, Maryam Tabrizian
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 640 (2022)
The metal complex copper diethyldithiocarbamate (CuET) induces cancer cell death by inhibiting protein degradation and induces proteotoxic stress, making CuET a promising cancer therapeutic. However, no clinical formulation of CuET exists to date as
Externí odkaz:
https://doaj.org/article/9a7a1378cb3244ff93fef87229b73e23
Autor:
Jana Volejnikova, Jirina Zapletalova, Marie Jarosova, Helena Urbankova, Petr Vojta, Eva Klaskova, Marshall S. Horwitz, Marian Hajduch, Vladimir Mihal
Publikováno v:
Biomedical Papers, Vol 162, Iss 1, Pp 65-70 (2018)
Background: Leri-Weill syndrome (LWS) ranks among conditions with short stature homeobox gene (SHOX) haploinsufficiency. Data on possible association of SHOX aberrations with malignant diseases are scarce. Methods and Results: We report a unique case
Externí odkaz:
https://doaj.org/article/587fce9b91bd4cf8b81ee17a06ff42b2
Autor:
Zuzana Capkova, Pavlina Capkova, Josef Srovnal, Katerina Staffova, Vera Becvarova, Marie Trkova, Katerina Adamova, Alena Santava, Vaclava Curtisova, Marian Hajduch, Martin Prochazka
Publikováno v:
PeerJ, Vol 7, p e7979 (2019)
Background Autism spectrum disorders (ASD) and intellectual disabilities (ID) are heterogeneous and complex developmental diseases with significant genetic backgrounds and overlaps of genetic susceptibility loci. Copy number variants (CNVs) are known
Externí odkaz:
https://doaj.org/article/53b88db70a184c60b74f990519ae0e3b
Autor:
Jana Volejnikova, Viera Bajciova, Lucie Sulovska, Marie Geierova, Eva Buriankova, Marie Jarosova, Marian Hajduch, Jaroslav Sterba, Vladimir Mihal
Publikováno v:
Biomedical Papers, Vol 160, Iss 3, Pp 456-460 (2016)
Background: Malignant melanoma in childhood is infrequent and can arise within congenital melanocytic nevi. Spread of malignant melanoma to the bone marrow, especially in children, is extremely rare. Methods and Results: Reported is a case of a 5-yea
Externí odkaz:
https://doaj.org/article/6642853b11b54c34a6bc5b5a6470413c
Autor:
Zbynek Novy, Volodymyr Lobaz, Martin Vlk, Jan Kozempel, Petr Stepanek, Miroslav Popper, Jana Vrbkova, Marian Hajduch, Martin Hruby, Milos Petrik
Publikováno v:
Nanomaterials, Vol 10, Iss 9, p 1690 (2020)
Nanoparticles (NPs) represent an emerging platform for diagnosis and treatment of various diseases such as cancer, where they can take advantage of enhanced permeability and retention (EPR) effect for solid tumor accumulation. To improve their colloi
Externí odkaz:
https://doaj.org/article/1a28b2b1d6ac44eab4bdfce3ae04cef0
Autor:
Radka Filipcikova, Ivana Oborna, Jana Brezinova, Jiri Novotny, Gabriella Wojewodka, Juan Bautista De Sanctis, Lenka Radova, Marian Hajduch, Danuta Radzioch
Publikováno v:
Biomedical Papers, Vol 159, Iss 1, Pp 077-082 (2015)
Aims: Male infertility has been associated with imbalance in the polyunsaturated fatty acids arachidonic acid/docosahexaenoic acid (AA/DHA) ratio. This study aimed to assess whether use of the potent antioxidant, lycopene, would affect this imbalance
Externí odkaz:
https://doaj.org/article/4e8d45d28b7d46428cb537af99941ad7
Autor:
Marianne Fleuti, Tania Sanchez-Quirante, Lenka Poštová Slavětínská, Eva Tloušt'ová, Michal Tichý, Soňa Gurská, Petr Džubák, Marián Hajdúch, Michal Hocek
Publikováno v:
ACS Omega, Vol 9, Iss 18, Pp 20557-20570 (2024)
Externí odkaz:
https://doaj.org/article/9fd51b42b0dc460dae1b9022e978c82e