Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Maria, Strassburger"'
Autor:
Victor Brantl, Jana M. Boysen, Annie Yap, Evgeny Golubtsov, Dominik Ruf, Thorsten Heinekamp, Maria Straßburger, Karl Dichtl, Hubertus Haas, Falk Hillmann, Johannes Wagener
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Aspergillus fumigatus is an important fungal pathogen that causes allergic reactions but also life-threatening infections. One of the most abundant A. fumigatus proteins is Asp f3. This peroxiredoxin is a major fungal allergen and known for
Externí odkaz:
https://doaj.org/article/6522a73eeb674cb7804e17e5e00d975e
Autor:
Dean Frawley, Maria C. Stroe, Berl R. Oakley, Thorsten Heinekamp, Maria Straßburger, Alastair B. Fleming, Axel A. Brakhage, Özgür Bayram
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
In order for eukaryotes to efficiently detect and respond to environmental stimuli, a myriad of protein signaling pathways are utilized. An example of highly conserved signaling pathways in eukaryotes are the mitogen-activated protein kinase (MAPK) p
Externí odkaz:
https://doaj.org/article/798e6968524144d2a4aea6fe601bc40c
Autor:
Lukas Birštonas, Alex Dallemulle, Manuel S. López-Berges, Ilse D. Jacobsen, Martin Offterdinger, Beate Abt, Maria Straßburger, Ingo Bauer, Oliver Schmidt, Bettina Sarg, Herbert Lindner, Hubertus Haas, Fabio Gsaller
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Selectable markers are indispensable for genetic engineering, yet their number and variety are limited. Most selection procedures for prototrophic cells rely on the introduction of antibiotic resistance genes. New minimally invasive tools ar
Externí odkaz:
https://doaj.org/article/1b785454018f47a2a970ea48abd09134
Autor:
Bianca Hoffmann, Carl-Magnus Svensson, Maria Straßburger, Björn Gebser, Ingo M. Irmler, Thomas Kamradt, Hans Peter Saluz, Marc Thilo Figge
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The assessment of bone damage is required to evaluate disease severity and treatment efficacy both in arthritis patients and in experimental arthritis models. Today there is still a lack of in vivo methods that enable the quantification of a
Externí odkaz:
https://doaj.org/article/cacc0218165e466c83adae775fca26db
Autor:
Adriana Oliveira Manfiolli, Filipe Silva Siqueira, Thaila Fernanda dos Reis, Patrick Van Dijck, Sanne Schrevens, Sandra Hoefgen, Martin Föge, Maria Straßburger, Leandro José de Assis, Thorsten Heinekamp, Marina Campos Rocha, Slavica Janevska, Axel A. Brakhage, Iran Malavazi, Gustavo H. Goldman, Vito Valiante
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The pathogenic fungus Aspergillus fumigatus is able to adapt to extremely variable environmental conditions. The A. fumigatus genome contains four genes coding for mitogen-activated protein kinases (MAPKs), which are important regulatory kno
Externí odkaz:
https://doaj.org/article/2a88a6e1f3f546b38da33b11a7706562
Autor:
Vera Voltersen, Matthew G. Blango, Sahra Herrmann, Franziska Schmidt, Thorsten Heinekamp, Maria Strassburger, Thomas Krüger, Petra Bacher, Jasmin Lother, Esther Weiss, Kerstin Hünniger, Hong Liu, Peter Hortschansky, Alexander Scheffold, Jürgen Löffler, Sven Krappmann, Sandor Nietzsche, Oliver Kurzai, Hermann Einsele, Olaf Kniemeyer, Scott G. Filler, Utz Reichard, Axel A. Brakhage
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Aspergillus fumigatus is a common airborne fungal pathogen of humans and a significant source of mortality in immunocompromised individuals. Here, we provide the most extensive cell wall proteome profiling to date of A. fumigatus resting con
Externí odkaz:
https://doaj.org/article/9fe5a0ecbee347959685d1702c23f58a
Autor:
Nanbiao Long, Thomas Orasch, Shizhu Zhang, Lu Gao, Xiaoling Xu, Peter Hortschansky, Jing Ye, Fenli Zhang, Kai Xu, Fabio Gsaller, Maria Straßburger, Ulrike Binder, Thorsten Heinekamp, Axel A Brakhage, Hubertus Haas, Ling Lu
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007762 (2018)
Both branched-chain amino acids (BCAA) and iron are essential nutrients for eukaryotic cells. Previously, the Zn2Cys6-type transcription factor Leu3/LeuB was shown to play a crucial role in regulation of BCAA biosynthesis and nitrogen metabolism in S
Externí odkaz:
https://doaj.org/article/be69d7fd105d4bbb84fc6f1c2324f420
Autor:
Lei-Jie Jia, Muhammad Rafiq, Lukáš Radosa, Peter Hortschansky, Cristina Cunha, Zoltán Cseresnyés, Thomas Krüger, Franziska Schmidt, Thorsten Heinekamp, Maria Straßburger, Bettina Löffler, Torsten Doenst, João F. Lacerda, António Campos, Marc Thilo Figge, Agostinho Carvalho, Olaf Kniemeyer, Axel A. Brakhage
© 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
The decision whether endosomes enter the degradative or recycling pathway in mamm
The decision whether endosomes enter the degradative or recycling pathway in mamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee970f29a24030ab41a20db2d32e6be8
https://hdl.handle.net/10451/56653
https://hdl.handle.net/10451/56653
Autor:
Anna Johns, Daniel H. Scharf, Fabio Gsaller, Hella Schmidt, Thorsten Heinekamp, Maria Straßburger, Jason D. Oliver, Mike Birch, Nicola Beckmann, Katharine S. Dobb, Jane Gilsenan, Bharatkumar Rash, Elaine Bignell, Axel A. Brakhage, Michael J. Bromley
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Secondary metabolites are key mediators of virulence for many pathogens. Aspergillus fumigatus produces a vast array of these bioactive molecules, the biosynthesis of which is catalyzed by nonribosomal peptide synthetases (NRPSs) or polyketi
Externí odkaz:
https://doaj.org/article/cccea62e55644309b3c3b177d1c49935
Autor:
Lei-Jie Jia, Muhammad Rafiq, Lukáš Radosa, Peter Hortschansky, Cristina Cunha, Zoltán Cseresnyés, Thomas Krüger, Franziska Schmidt, Thorsten Heinekamp, Maria Straßburger, Bettina Löffler, Torsten Doenst, João F. Lacerda, António Campos, Marc Thilo Figge, Agostinho Carvalho, Olaf Kniemeyer, Axel A. Brakhage
SummaryThe analysis of host-pathogen interactions bears the potential to discover novel pathogenicity mechanisms and to obtain novel insights into basic mechanisms of cell biology. Here, we obtained unprecedented insight into both. We discovered that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1cadfcef2ee9ead335be7d92143f7de
https://doi.org/10.1101/2022.05.18.492126
https://doi.org/10.1101/2022.05.18.492126