Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Maria, Pierdomenico"'
Autor:
Peter H, Hagedorn, Jeffrey M, Brown, Amy, Easton, Maria, Pierdomenico, Kelli, Jones, Richard E, Olson, Stephen E, Mercer, Dong, Li, James, Loy, Anja M, Høg, Marianne L, Jensen, Martin, Gill, Angela M, Cacace
Publikováno v:
Nucleic Acid Therapeutics. 32:151-162
Antisense oligonucleotides are a relatively new therapeutic modality and safety evaluation is still a developing area of research. We have observed that some oligonucleotides can produce acute, nonhybridization dependent, neurobehavioral side effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84306dc3fdd2daeba90224f662941fbf
https://doi.org/10.1089/nat.2021.0071
https://doi.org/10.1089/nat.2021.0071
Autor:
Maria Pierdomenico, Franscesca Palone, Vincenzo Cesi, Roberta Vitali, Anna Barbara Mancuso, Salvatore Cucchiara, Salvatore Oliva, Marina Aloi, Laura Stronati
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background and aims: Recent evidences reveal the occurrence of a close relationship among epithelial to mesenchymal transition (EMT), chronic inflammation and fibrosis. ZNF281 is an EMT-inducing transcription factor (EMT-TF) involved in the regulatio
Externí odkaz:
https://doaj.org/article/14a7e346e8f54ec6b2723a9283f3cd38
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 41:1586-1602
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe34c82774989bbb5d91570ae65b388
https://doi.org/10.1080/07391102.2021.2023642
https://doi.org/10.1080/07391102.2021.2023642
Pomegranate is an important source of bioactive molecules with proven beneficial effects on human health. The aim of this study was to investigate the potential anti-inflammatory effect of a pomegranate extract (PE), obtained from the whole fruit and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8192d8b5e6b9cf29fc8a94aedc7337b
Autor:
Rosanna Pinto, Mariateresa Mancuso, Carmela Marino, Emanuela Pasquali, Claudia Consales, Caterina Merla, Maria Pierdomenico, Vanni Lopresto, Barbara Benassi, Alessio Butera
Publikováno v:
Molecular Neurobiology
We here characterize the response to the extremely low-frequency (ELF) magnetic field (MF, 50 Hz, 1 mT) of SH-SY5Y human neuroblastoma cells, cultured in a three-dimensional (3D) Alvetex® scaffold compared to conventional two-dimensional (2D) monola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2dc43ca0f4797af128bc9dcbf90b12
http://europepmc.org/articles/PMC7932966
http://europepmc.org/articles/PMC7932966
Autor:
Jeremy H. Toyn, Lorin A. Thompson, Kimberley A. Lentz, Jere E. Meredith, Catherine R. Burton, Sethu Sankaranararyanan, Valerie Guss, Tracey Hall, Lawrence G. Iben, Carol M. Krause, Rudy Krause, Xu-Alan Lin, Maria Pierdomenico, Craig Polson, Alan S. Robertson, R. Rex Denton, James E. Grace, John Morrison, Joseph Raybon, Xiaoliang Zhuo, Kimberly Snow, Ramesh Padmanabha, Michele Agler, Kim Esposito, David Harden, Margaret Prack, Sam Varma, Victoria Wong, Yingjie Zhu, Tatyana Zvyaga, Samuel Gerritz, Lawrence R. Marcin, Mendi A. Higgins, Jianliang Shi, Cong Wei, Joseph L. Cantone, Dieter M. Drexler, John E. Macor, Richard E. Olson, Michael K. Ahlijanian, Charles F. Albright
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2014 (2014)
Alzheimer’s disease is the most prevalent cause of dementia and is associated with accumulation of amyloid-β peptide (Aβ), particularly the 42-amino acid Aβ1-42, in the brain. Aβ1-42 levels can be decreased by γ-secretase modulators (GSM), whi
Externí odkaz:
https://doaj.org/article/1dce320132d4411583a19dcbfe2b54ae
Autor:
Manuela Costanzo, Laura Stronati, Salvatore Cucchiara, Roberta Vitali, Maria Pierdomenico, Anna Negroni, Francesca Palone, Eleonora Colantoni, Vincenzo Cesi
Publikováno v:
Inflammation Research. 65:803-813
The importance of autophagy in mechanisms underlying inflammation has been highlighted. Downstream effects of the bacterial sensor NOD2 include autophagy induction. Recently, a relationship between defects in autophagy and adherent/invasive Escherich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b7fff478e99cc65f63390d33f8840d
https://doi.org/10.1007/s00011-016-0964-8
https://doi.org/10.1007/s00011-016-0964-8
Publikováno v:
Journal of Inflammation Research
The nucleotide-binding oligomerization domain (NOD) protein, NOD2, belonging to the intracellular NOD-like receptor family, detects conserved motifs in bacterial peptidoglycan and promotes their clearance through activation of a proinflammatory trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfa0cf3191292e55a0b2a35157c8931
https://pubmed.ncbi.nlm.nih.gov/29483781
https://pubmed.ncbi.nlm.nih.gov/29483781
Autor:
Anna Maria, Pierdomenico, Sara, Patruno, Marilina, Codagnone, Felice, Simiele, Veronica Cecilia, Mari, Roberto, Plebani, Antonio, Recchiuti, Mario, Romano
Publikováno v:
Scientific Reports
The involvement of microRNA (miR) in cystic fibrosis (CF) pathobiology is rapidly emerging. We previously documented that miR-181b controls the expression of the ALX/FPR2 receptor, which is recognized by the endogenous proresolution ligand, lipoxin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5714758ef0de9dd835601810edc50c23
https://pubmed.ncbi.nlm.nih.gov/29044225
https://pubmed.ncbi.nlm.nih.gov/29044225
Autor:
Anna Negroni, Eleonora Colantoni, Antonio Tiberti, Manuela Costanzo, Laura Stronati, Maria Pierdomenico, Francesca Palone, Salvatore Cucchiara, Salvatore Oliva
Background Necroptosis is an inflammatory form of programmed cell death requiring receptor-interacting protein kinase 3 (RIP3) and mixed lineage kinase domain-like protein (MLKL). Aims The aim of this study is to examine in depth in vitro and ex vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebf75704f5a40df62aa652a8540ce3a
http://hdl.handle.net/11573/1008540
http://hdl.handle.net/11573/1008540