Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Maria, O'Donovan"'
Autor:
Kenza Bouzid, Harshita Sharma, Sarah Killcoyne, Daniel C. Castro, Anton Schwaighofer, Max Ilse, Valentina Salvatelli, Ozan Oktay, Sumanth Murthy, Lucas Bordeaux, Luiza Moore, Maria O’Donovan, Anja Thieme, Aditya Nori, Marcel Gehrung, Javier Alvarez-Valle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Timely detection of Barrett’s esophagus, the pre-malignant condition of esophageal adenocarcinoma, can improve patient survival rates. The Cytosponge-TFF3 test, a non-endoscopic minimally invasive procedure, has been used for diagnosing in
Externí odkaz:
https://doaj.org/article/a7d26ad27adf4210ba573b93bfdee22b
Autor:
Nastazja D. Pilonis, Maria O’Donovan, Susan Richardson, Rebecca C. Fitzgerald, Massimiliano di Pietro
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Recognition of early signet-ring cell carcinoma (SRCC) in patients with hereditary diffuse gastric cancer (HDGC) undergoing endoscopic surveillance is challenging. We hypothesized that probe-based confocal laser endomicroscopy (pC
Externí odkaz:
https://doaj.org/article/2e61d88a4c9442fd89d09bf0c62154e8
Autor:
Judith Honing, W Keith Tan, Egle Dieninyte, Maria O'Donovan, Lodewijk Brosens, Bas Weusten, Massimiliano di Pietro
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287587 (2023)
BackgroundGastric atrophy (GA) and gastric intestinal metaplasia (GIM) are precursor conditions to gastric adenocarcinoma (GAC) and should be monitored endoscopically in selected individuals. However, little is known about adherence to recommendation
Externí odkaz:
https://doaj.org/article/e0f870eb0119496285ac07a308440ac2
Autor:
Christopher M. Jones, Heather O'Connor, Maria O'Donovan, Daniel Hayward, Adrienn Blasko, Ruth Harman, Shalini Malhotra, Irene Debiram-Beecham, Bincy Alias, Adam Bailey, Andrew Bateman, Tom D.L. Crosby, Stephen Falk, Simon Gollins, Maria A. Hawkins, Sudarshan Kadri, Stephanie Levy, Ganesh Radhakrishna, Rajarshi Roy, Raj Sripadam, Rebecca C. Fitzgerald, Somnath Mukherjee
Publikováno v:
EClinicalMedicine, Vol 53, Iss , Pp 101664- (2022)
Summary: Background: Effective surveillance strategies are required for patients diagnosed with oesophageal squamous cell carcinoma (OSCC) or adenocarcinoma (OAC) for whom chemoradiotherapy (CRT) is used as a potentially-curative, organ-sparing, alte
Externí odkaz:
https://doaj.org/article/691654243a41434aa0d1850669448664
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104160- (2022)
Summary: Background: Intestinal metaplasia (IM) is pre-neoplastic with variable cancer risk. Cytosponge-TFF3 test can detect IM. We aimed to 1) assess whether quantitative TFF3 scores can distinguish clinically relevant Barrett's oesophagus (BO) (C
Externí odkaz:
https://doaj.org/article/69d631ddab0342ce8ad983a02e809fef
Autor:
Karol Nowicki-Osuch, Lizhe Zhuang, Tik Shing Cheung, Emily L. Black, Neus Masqué-Soler, Ginny Devonshire, Aisling M. Redmond, Adam Freeman, Massimilliano di Pietro, Nastazja Pilonis, Wladyslaw Januszewicz, Maria O'Donovan, Simon Tavaré, Jacqueline D. Shields, Rebecca C. Fitzgerald
Publikováno v:
Cancer Discovery. :OF1-OF18
Intestinal metaplasia in the esophagus (Barrett's esophagus IM, or BE-IM) and stomach (GIM) are considered precursors for esophageal and gastric adenocarcinoma, respectively. We hypothesize that BE-IM and GIM follow parallel developmental trajectorie
Autor:
Wladyslaw Januszewicz, Vinod V. Subhash, William Waldock, Daniel I. Fernando, Giorgio Bartalucci, Hamza Chettouh, Ahmad Miremadi, Maria O'Donovan, Rebecca C. Fitzgerald, Massimiliano di Pietro
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102877- (2020)
Background: Radiofrequency ablation (RFA) is an effective treatment for dysplastic Barrett's esophagus (BE), but recurrence can occur after initial response. Currently there is uncertainty about how to best define histological remission. A DNA methyl
Externí odkaz:
https://doaj.org/article/06f7be705bce41bb912b74d7c6a398f9
Autor:
Judith Offman, Beth Muldrew, Maria O’Donovan, Irene Debiram-Beecham, Francesca Pesola, Irene Kaimi, Samuel G. Smith, Ashley Wilson, Zohrah Khan, Pierre Lao-Sirieix, Benoit Aigret, Fiona M. Walter, Greg Rubin, Steve Morris, Christopher Jackson, Peter Sasieni, Rebecca C. Fitzgerald, on behalf of the BEST3 Trial team
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-16 (2018)
Abstract Background Early detection of oesophageal cancer improves outcomes; however, the optimal strategy for identifying patients at increased risk from the pre-cancerous lesion Barrett’s oesophagus (BE) is not clear. The Cytosponge, a novel non-
Externí odkaz:
https://doaj.org/article/f6590acc1c364b1b878a6618947918f6
Autor:
Rebecca Landy, Sarah Killcoyne, Charlene Tang, Stephanie Juniat, Maria O’Donovan, Neha Goel, Marcel Gehrung, Rebecca C Fitzgerald
Publikováno v:
QJM: An International Journal of Medicine.
Background COVID-19 curtailed endoscopy services adding to diagnostic backlogs. Building on trial evidence for a non-endoscopic oesophageal cell collection device coupled with biomarkers (Cytosponge), a pilot implementation was launched for patients
Autor:
Rebecca C. Fitzgerald, Jacqueline D. Shields, Simon Tavaré, Maria O'Donovan, Wladyslaw Januszewicz, Nastazja Pilonis, Massimilliano di Pietro, Adam Freeman, Aisling M. Redmond, Ginny Devonshire, Neus Masqué-Soler, Emily L. Black, Tik Shing Cheung, Lizhe Zhuang, Karol Nowicki-Osuch
This table contains marker genes identified in the pairwise comparison of clusters identified in fibroblast population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9faec736952c3cecb9a79a71d09694f6
https://doi.org/10.1158/2159-8290.22841344.v1
https://doi.org/10.1158/2159-8290.22841344.v1