Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Maria, Litovchenko"'
Autor:
Joern Pezoldt, Carolin Wiechers, Mangge Zou, Maria Litovchenko, Marjan Biocanin, Michael Beckstette, Katarzyna Sitnik, Martina Palatella, Guido van Mierlo, Wanze Chen, Vincent Gardeux, Stefan Floess, Maria Ebel, Julie Russeil, Panagiota Arampatzi, Ehsan Vafardanejad, Antoine-Emmanuel Saliba, Bart Deplancke, Jochen Huehn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Lymph nodes in various locations of the body differ in their cell composition and gene expression signatures. Here authors show that the rapid postnatal expansion of lymph nodes is governed by CD34 + stromal cells and fibroblastic reticular stromal c
Externí odkaz:
https://doaj.org/article/a6cebd9a2df24f8cacb6093aef1fff24
Autor:
Gerard Llimos, Vincent Gardeux, Ute Koch, Judith F. Kribelbauer, Antonina Hafner, Daniel Alpern, Joern Pezoldt, Maria Litovchenko, Julie Russeil, Riccardo Dainese, Riccardo Moia, Abdurraouf Mokhtar Mahmoud, Davide Rossi, Gianluca Gaidano, Christoph Plass, Pavlo Lutsik, Clarissa Gerhauser, Sebastian M. Waszak, Alistair Boettiger, Freddy Radtke, Bart Deplancke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Non-coding variants can regulate transcription factor binding and gene expression at variable chromatin modules. Here, the authors show that a germline variant induces transcription factor nucleation through chromatin compaction leading to AXIN2 up-r
Externí odkaz:
https://doaj.org/article/a45f0167b2ac4647bf70d5df2f44a6e7
Autor:
Michael V. Frochaux, Maroun Bou Sleiman, Vincent Gardeux, Riccardo Dainese, Brian Hollis, Maria Litovchenko, Virginie S. Braman, Tommaso Andreani, Dani Osman, Bart Deplancke
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-19 (2020)
Abstract Background Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but
Externí odkaz:
https://doaj.org/article/8e53e953bb0541ca9e5d26a86a654e52
Autor:
Dali Ma, Maroun Bou-Sleiman, Pauline Joncour, Claire-Emmanuelle Indelicato, Michael Frochaux, Virginie Braman, Maria Litovchenko, Gilles Storelli, Bart Deplancke, François Leulier
Publikováno v:
iScience, Vol 19, Iss , Pp 436-447 (2019)
Summary: Eukaryotic genomes encode several buffering mechanisms that robustly maintain invariant phenotypic outcome despite fluctuating environmental conditions. Here we show that the Drosophila gut-associated commensals, represented by a single facu
Externí odkaz:
https://doaj.org/article/717b08a23ff34195b8d976e5dd76f49e
Autor:
Aaron F. McDaid, Peter K. Joshi, Eleonora Porcu, Andrea Komljenovic, Hao Li, Vincenzo Sorrentino, Maria Litovchenko, Roel P. J. Bevers, Sina Rüeger, Alexandre Reymond, Murielle Bochud, Bart Deplancke, Robert W. Williams, Marc Robinson-Rechavi, Fred Paccaud, Valentin Rousson, Johan Auwerx, James F. Wilson, Zoltán Kutalik
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Along with various environmental factors, a complex genetic architecture influences human lifespan. Here, McDaid and colleagues reveal novel loci associated with human lifespan and linked biomarkers by Bayesian association scan.
Externí odkaz:
https://doaj.org/article/0f5ed7735c3c4bb88a8cf53a6ce62f91
Autor:
James R.M. Black, Thomas P. Jones, Carlos Martínez-Ruiz, Maria Litovchenko, Clare Puttick, Nicholas McGranahan
A central goal of cancer research is the identification of cancer genes that drive tumour growth and progression. Existing approaches to this problem typically leverage frequentist approaches based on patterns of somatic mutagenesis in DNA. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aea5996df0e7714c44acc3adf3f7dc9b
https://doi.org/10.1101/2023.03.09.531725
https://doi.org/10.1101/2023.03.09.531725
Autor:
Magda Zachara, Pernille Y Rainer, Horia Hashimi, Julie M Russeil, Daniel Alpern, Radiana Ferrero, Maria Litovchenko, Bart Deplancke
Publikováno v:
The EMBO journal. 41(18)
Adipose stem and precursor cells (ASPCs) give rise to adipocytes and determine the composition and plasticity of adipose tissue. Recently, several studies have demonstrated that ASPCs partition into at least three distinct cell subpopulations, includ
Publikováno v:
Nucleic Acids Research
Single-cell omics enables researchers to dissect biological systems at a resolution that was unthinkable just 10 years ago. However, this analytical revolution also triggered new demands in ‘big data’ management, forcing researchers to stay up to
Autor:
Matthew R. Robinson, Brian Hollis, Johan Auwerx, Adamandia Kapopoulou, Roel P. J. Bevers, Bart Deplancke, Maria Litovchenko, Virginie S. Braman
Publikováno v:
Nature Metabolism. 1:1226-1242
The nature and extent of mitochondrial DNA variation in a population and how it affects traits is poorly understood. Here we resequence the mitochondrial genomes of 169 Drosophila Genetic Reference Panel lines, identifying 231 variants that stratify
Autor:
Marjan Biočanin, Vincent Gardeux, Maria Litovchenko, Panagiota Arampatzi, Stefan Floess, Michael Beckstette, Wanze Chen, Antoine-Emmanuel Saliba, Ehsan Vafardanejad, Katarzyna M. Sitnik, Jochen Huehn, Carolin Wiechrs, Maria Ebel, Joern Pezoldt, Julie Russeil, Bart Deplancke, Mangge Zou
Gut-draining mesenteric lymph nodes (mLN) provide the framework and microenvironment to shape intestinal adaptive immune responses. We previously delineated transcriptional signatures in LN stromal cells (SC), pointing to tissue-specific variability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8821aea0c2f0f5fd719d68242e082e6
https://doi.org/10.21203/rs.3.rs-596484/v1
https://doi.org/10.21203/rs.3.rs-596484/v1