Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Maria, Fazzari"'
Autor:
Giulia Lunghi, Erika Di Biase, Emma Veronica Carsana, Alexandre Henriques, Noelle Callizot, Laura Mauri, Maria Grazia Ciampa, Luigi Mari, Nicoletta Loberto, Massimo Aureli, Sandro Sonnino, Michael Spedding, Elena Chiricozzi, Maria Fazzari
Publikováno v:
FEBS Open Bio, Vol 13, Iss 12, Pp 2324-2341 (2023)
Alterations in glycosphingolipid metabolism have been linked to the pathophysiological mechanisms of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting motor neurons. Accordingly, administration of GM1, a sialic acid‐contain
Externí odkaz:
https://doaj.org/article/bc90ee2630b94cd7baec16a20f019b9f
Publikováno v:
FEBS Open Bio, Vol 11, Iss 12, Pp 3193-3200 (2021)
Gangliosides are particularly abundant in the central nervous system, where they are mainly associated with the synaptic membranes. Their structure underlies a specific role in determining several cell physiological processes of the nervous system. T
Externí odkaz:
https://doaj.org/article/eb22c8b319e8439896d7dc9d57e2ea93
Autor:
Maria Fazzari, Giulia Lunghi, Alexandre Henriques, Noëlle Callizot, Maria Grazia Ciampa, Laura Mauri, Simona Prioni, Emma Veronica Carsana, Nicoletta Loberto, Massimo Aureli, Luigi Mari, Sandro Sonnino, Elena Chiricozzi, Erika Di Biase
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1305 (2023)
Past evidence has shown that the exogenous administration of GM1 ganglioside slowed neuronal death in preclinical models of Parkinson’s disease, a neurodegenerative disorder characterized by the progressive loss of dopamine-producing neurons: howev
Externí odkaz:
https://doaj.org/article/8a1943fc716f42f4923a8d9f878d1326
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 363 (2022)
Gangliosides are glycosphingolipids which are particularly abundant in the plasma membrane of mammalian neurons. The knowledge of their presence in the human brain dates back to the end of 19th century, but their structure was determined much later,
Externí odkaz:
https://doaj.org/article/214647c3fe6a49b388335d7598109068
Autor:
Giulia Lunghi, Maria Fazzari, Maria Grazia Ciampa, Laura Mauri, Erika Di Biase, Elena Chiricozzi, Sandro Sonnino
Publikováno v:
FEBS Letters. 596:3124-3132
The interactions between gangliosides and proteins belonging to the same or different lipid domains and their influence on physiological and pathological states have been analysed in detail. A well-known factor impacting on lipid-protein interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12198c9ad56391755f760ab1b111ac02
https://doi.org/10.1002/1873-3468.14532
https://doi.org/10.1002/1873-3468.14532
Autor:
Isabella Barbiero, Davide Valente, Chetan Chandola, Fiorenza Magi, Anna Bergo, Laura Monteonofrio, Marco Tramarin, Maria Fazzari, Silvia Soddu, Nicoletta Landsberger, Cinzia Rinaldo, Charlotte Kilstrup-Nielsen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The cyclin-dependent kinase-like 5 (CDKL5) gene has been associated with rare neurodevelopmental disorders characterized by the early onset of seizures and intellectual disability. The CDKL5 protein is widely expressed in most tissues and ce
Externí odkaz:
https://doaj.org/article/fbcbc72f52974687a41eb08fed046097
Publikováno v:
Glycoconjugate Journal. 39:27-38
GM1 is a crucial component of neuronal membrane residing both in the soma and nerve terminals. As reported in Parkinson’s disease patients, the reduction of GM1 determines the failure of fundamental functional processes leading to cumulative cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3645d74bb2fdc159a1657c98bbf843e
https://doi.org/10.1007/s10719-021-10019-7
https://doi.org/10.1007/s10719-021-10019-7
Publikováno v:
FEBS Open Bio, Vol 11, Iss 12, Pp 3193-3200 (2021)
FEBS Open Bio
FEBS Open Bio
Gangliosides are particularly abundant in the central nervous system, where they are mainly associated with the synaptic membranes. Their structure underlies a specific role in determining several cell physiological processes of the nervous system. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5446ddc40a68c66f5bd3c74ad009dded
https://doaj.org/article/eb22c8b319e8439896d7dc9d57e2ea93
https://doaj.org/article/eb22c8b319e8439896d7dc9d57e2ea93
Autor:
Nicoletta Loberto, Laura Mauri, Maria Fazzari, Giulia Lunghi, Elena Chiricozzi, Massimo Aureli, Erika Di Biase, Sandro Sonnino
Publikováno v:
Glycoconjugate Journal
It is well over a century that glycosphingolipids are matter of interest in different fields of research. The hydrophilic oligosaccharide and the lipid moiety, the ceramide, both or separately have been considered in different moments as the crucial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10b72f48c7d12c68cdbcc3eef4535a1
http://europepmc.org/articles/PMC7917043
http://europepmc.org/articles/PMC7917043
Autor:
Maria Fazzari, Giulia Lunghi, Pamela Fato, Maura Samarani, Erika Di Biase, Maria Grazia Ciampa, Diego Yuri Pomè, Simona Prioni, Manuela Valsecchi, Margherita Maggioni, Sandro Sonnino, Elena Chiricozzi, Laura Mauri
Publikováno v:
Glycoconjugate Journal. 37:329-343
It has been recently reported by our group that GM1-oligosaccharide added to neuroblastoma cells or administered to mouse experimental model mimics the neurotrophic and neuroprotective properties of GM1 ganglioside. In addition to this, differently f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3577ac02658450d970b7a677587afd32
https://doi.org/10.1007/s10719-020-09919-x
https://doi.org/10.1007/s10719-020-09919-x