Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Maria, Elena Bottazzi"'
Autor:
Peter J. Hotez, Maria Elena Bottazzi, Nelufa Yesmin Islam, Jungsoon Lee, Jeroen Pollet, Cristina Poveda, Ulrich Strych, Syamala Rani Thimmiraju, Nestor L. Uzcategui, Leroy Versteeg, Daniel Gorelick
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 535-545 (2024)
ABSTRACTIntroduction Zebrafishes represent a proven model for human diseases and systems biology, exhibiting physiological and genetic similarities and having innate and adaptive immune systems. However, they are underexplored for human vaccinology,
Externí odkaz:
https://doaj.org/article/7b5259018f2c4102869b765483e32b3f
Autor:
Syamala Rani Thimmiraju, Rakesh Adhikari, JeAnna R. Redd, Maria Jose Villar, Jungsoon Lee, Zhuyun Liu, Yi-Lin Chen, Suman Sharma, Amandeep Kaur, Nestor L. Uzcategui, Shannon E. Ronca, Wen-Hsiang Chen, Jason T. Kimata, Bin Zhan, Ulrich Strych, Maria Elena Bottazzi, Peter J. Hotez, Jeroen Pollet
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-5 (2024)
Abstract The development of broad-spectrum coronavirus vaccines is essential to prepare for future respiratory virus pandemics. We demonstrated broad neutralization by a trivalent subunit vaccine, formulating the receptor-binding domains of SARS-CoV,
Externí odkaz:
https://doaj.org/article/44e886df60de4b48bf25ffd2242f40b2
Publikováno v:
EClinicalMedicine, Vol 73, Iss , Pp 102670- (2024)
Externí odkaz:
https://doaj.org/article/23d83110863f417eba77ca412317029a
Autor:
Yifan Wu, Freedom M. Green, Stephen A. Shaw, Lauren J. Bonilla, Shannon E. Ronca, Maria Elena Bottazzi, Farrah Kheradmand, Jill E. Weatherhead
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101167- (2024)
Externí odkaz:
https://doaj.org/article/ec842f2a601947cb86ae5dac72f2658b
Autor:
Peter J. Hotez, Rakesh Adhikari, Wen-Hsiang Chen, Yi-Lin Chen, Portia Gillespie, Nelufa Y. Islam, Brian Keegan, Rakhi Tyagi Kundu, Jungsoon Lee, Zhuyun Liu, Jason T. Kimata, Numan Oezguen, Jeroen Pollet, Cristina Poveda, Kay Razavi, Shannon E. Ronca, Ulrich Strych, Syamala R. Thimmiraju, Leroy Versteeg, Maria Jose Villar-Mondragon, Junfei Wei, Bin Zhan, Maria Elena Bottazzi
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 495-500 (2023)
Introduction The development of a yeast-expressed recombinant protein-based vaccine technology co-developed with LMIC vaccine producers and suitable as a COVID-19 vaccine for global access is described. The proof-of-concept for developing a SARS-CoV-
Externí odkaz:
https://doaj.org/article/9dc912870f71410b853d29ac8af90252
Autor:
Syamala Rani Thimmiraju, Maria Jose Villar, Jason T. Kimata, Ulrich Strych, Maria Elena Bottazzi, Peter J. Hotez, Jeroen Pollet
Publikováno v:
Viruses, Vol 16, Iss 9, p 1492 (2024)
Over the past three years, new SARS-CoV-2 variants have continuously emerged, evolving to a point where an immune response against the original vaccine no longer provided optimal protection against these new strains. During this time, high-throughput
Externí odkaz:
https://doaj.org/article/86980087e3fe48809ff791f0d35f29d4
Autor:
Zongyuan Liu, Rebecca Ulrich vonBargen, April L. Kendricks, Kate Wheeler, Ana Carolina Leão, Krithivasan Sankaranarayanan, Danya A. Dean, Shelley S. Kane, Ekram Hossain, Jeroen Pollet, Maria Elena Bottazzi, Peter J. Hotez, Kathryn M. Jones, Laura-Isobel McCall
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Post-infectious conditions present major health burdens but remain poorly understood. In Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that successfully clear T. cruzi do not always improve clinical outcome
Externí odkaz:
https://doaj.org/article/ece30cfd780f4288923b0c11f864e0a8
Autor:
Yifan Wu, Grace Adeniyi-Ipadeola, Mahliyah Adkins-Threats, Matthew Seasock, Charlie Suarez-Reyes, Ricardo Fujiwara, Maria Elena Bottazzi, Lizhen Song, Jason C Mills, Jill E Weatherhead
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011930 (2024)
Ascariasis (roundworm) is the most common parasitic helminth infection globally and can lead to significant morbidity in children including chronic lung disease. Children become infected with Ascaris spp. via oral ingestion of eggs. It has long been
Externí odkaz:
https://doaj.org/article/58aaa56739b04216aef9c58c235176ad
Autor:
William R. Lykins, Jeroen Pollet, Jessica A. White, Brian Keegan, Leroy Versteeg, Ulrich Strych, Wen-Hsiang Chen, Raodoh Mohamath, Gabi Ramer-Denisoff, Sierra Reed, Samuel Beaver, Alana Gerhardt, Emily A. Voigt, Mark A. Tomai, Robert Sitrin, Robert K. M. Choy, Frederick J. Cassels, Peter J. Hotez, Maria Elena Bottazzi, Christopher B. Fox
Publikováno v:
Frontiers in Drug Delivery, Vol 4 (2024)
Introduction: Since their introduction, adjuvanted recombinant subunit vaccines against COVID-19 have played a pivotal role in protecting global populations. Optimizing the immune response’s quality, amplitude, and durability to these vaccines depe
Externí odkaz:
https://doaj.org/article/f548c0f6edd64e56889f7e3269b838a0
Autor:
Duc Minh Nguyen, Cristina Poveda, Jeroen Pollet, Fabian Gusovsky, Maria Elena Bottazzi, Peter J Hotez, Kathryn Marie Jones
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011519 (2023)
BackgroundChagas disease, chronic infection with Trypanosoma cruzi, mainly manifests as cardiac disease. However, the liver is important for both controlling parasite burdens and metabolizing drugs. Notably, high doses of anti-parasitic drug benznida
Externí odkaz:
https://doaj.org/article/1a67838d992942c3894c9ef56f930384