Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Maria, Dusinska"'
Autor:
Ineke MALSCH, Evert Bouman, Panagiotis Isigonis, Georgia Melagraki, Antreas Afantitis, Maria Dusinska
Publikováno v:
Open Research Europe, Vol 3 (2024)
Risk governance of nanomaterials and nanotechnologies has been traditionally mainly limited to risk assessment, risk management and life cycle assessment. Recent approaches have experimented with widening the scope and including economic, social, and
Externí odkaz:
https://doaj.org/article/98c1d4f7a9054d6a9d9fcc454deb3820
Autor:
Marc Audebert, Ann-Sophie Assmann, Amaya Azqueta, Pavel Babica, Emilio Benfenati, Sylvie Bortoli, Peter Bouwman, Albert Braeuning, Tanja Burgdorf, Xavier Coumoul, Kloé Debizet, Maria Dusinska, Norman Ertych, Jörg Fahrer, Verena Fetz, Ludovic Le Hégarat, Adela López de Cerain, Harm J. Heusinkveld, Kevin Hogeveen, Miriam N. Jacobs, Mirjam Luijten, Giuseppa Raitano, Cynthia Recoules, Elise Rundén-Pran, Mariam Saleh, Iva Sovadinová, Martina Stampar, Lea Thibol, Céline Tomkiewicz, Ariane Vettorazzi, Bob Van de Water, Naouale El Yamani, Bojana Zegura, Michael Oelgeschläger
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Carcinogenic chemicals, or their metabolites, can be classified as genotoxic or non-genotoxic carcinogens (NGTxCs). Genotoxic compounds induce DNA damage, which can be detected by an established in vitro and in vivo battery of genotoxicity assays. Fo
Externí odkaz:
https://doaj.org/article/bb67b7cd857c45a58747146a121d489d
Autor:
Jeaphianne van Rijn, Antreas Afantitis, Mustafa Culha, Maria Dusinska, Thomas E. Exner, Nina Jeliazkova, Eleonora Marta Longhin, Iseult Lynch, Georgia Melagraki, Penny Nymark, Anastasios G. Papadiamantis, David A. Winkler, Hulya Yilmaz, Egon Willighagen
Publikováno v:
Journal of Cheminformatics, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Management of nanomaterials and nanosafety data needs to operate under the FAIR (findability, accessibility, interoperability, and reusability) principles and this requires a unique, global identifier for each nanomaterial. Existing identifi
Externí odkaz:
https://doaj.org/article/fd6b1e814a80496bbb6125ff5399c5b4
Autor:
Verona Buocikova, Silvia Tyciakova, Eleftherios Pilalis, Chara Mastrokalou, Maria Urbanova, Miroslava Matuskova, Lucia Demkova, Veronika Medova, Eleonora Marta Longhin, Elise Rundén-Pran, Maria Dusinska, Ivan Rios-Mondragon, Mihaela Roxana Cimpan, Alena Gabelova, Andrea Soltysova, Bozena Smolkova, Aristotelis Chatziioannou
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Decitabine (DAC), a DNA methyltransferase (DNMT) inhibitor, is tested in combination with conventional anticancer drugs as a treatment option for various solid tumors. Although epigenome modulation provides a promising avenue in treating resistant ca
Externí odkaz:
https://doaj.org/article/5bc2b77aace34b56b39120aa94a4b5ef
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
The Alamar Blue (AB) assay is widely used to investigate cytotoxicity, cell proliferation and cellular metabolic activity within different fields of toxicology. The use of the assay with nanomaterials (NMs) entails specific aspects including the pote
Externí odkaz:
https://doaj.org/article/0a3f2ab915a34481af0b110bfb87f664
Autor:
Elise Rundén-Pran, Espen Mariussen, Naouale El Yamani, Elisabeth Elje, Eleonora Marta Longhin, Maria Dusinska
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
To cope with the high number of nanomaterials manufactured, it is essential to develop high-throughput methods for in vitro toxicity screening. At the same time, the issue with interference of the nanomaterial (NM) with the read-out or the reagent of
Externí odkaz:
https://doaj.org/article/323d16bd0a264659a179d9d682a3f63d
Autor:
Stefano Bonassi, Marcello Ceppi, Peter Møller, Amaya Azqueta, Mirta Milić, Neri Monica, Gunnar Brunborg, Roger Godschalk, Gudrun Koppen, Sabine A. S. Langie, João Paulo Teixeira, Marco Bruzzone, Juliana Da Silva, Danieli Benedetti, Delia Cavallo, Cinzia Lucia Ursini, Lisa Giovannelli, Silvia Moretti, Patrizia Riso, Cristian Del Bo’, Patrizia Russo, Malgorzata Dobrzyńska, Irina A. Goroshinskaya, Ekaterina I. Surikova, Marta Staruchova, Magdalena Barančokova, Katarina Volkovova, Alena Kažimirova, Bozena Smolkova, Blanca Laffon, Vanessa Valdiglesias, Susana Pastor, Ricard Marcos, Alba Hernández, Goran Gajski, Biljana Spremo-Potparević, Lada Živković, Elisa Boutet-Robinet, Hervé Perdry, Pierre Lebailly, Carlos L. Perez, Nursen Basaran, Zsuzsanna Nemeth, Anna Safar, Maria Dusinska, Andrew Collins, for the hCOMET project
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, mortality by cause, and cancer in
Externí odkaz:
https://doaj.org/article/f8e27d7d62fb499faa7a487ea347b299
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Graphical Abstract
Externí odkaz:
https://doaj.org/article/8935d441cf8a49f187c2ae99b22b3512
Autor:
Renato Cardoso, Maria Dusinska, Andrew Collins, Mugimane Manjanatha, Stefan Pfuhler, Marilyn Registre, Rosalie Elespuru
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
The in vivo Comet assay measures the generation of DNA strand breaks under conditions in which the DNA will unwind and migrate to the anode in an electrophoresis assay, producing comet-like figures. Measurements are on single cells, which allows the
Externí odkaz:
https://doaj.org/article/3cafa7945b7d4bb8aa6758f86d11105e
Autor:
Rosalie K. Elespuru, Shareen H. Doak, Andrew R. Collins, Maria Dusinska, Stefan Pfuhler, Mugimane Manjanatha, Renato Cardoso, Connie L. Chen
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or indirect DNA interaction. Testing may be a surrogate for assessment of heritable genetic risk or carcinogenic risk. Testing of nanomaterials (NM) for
Externí odkaz:
https://doaj.org/article/2d21ba7877bd47e2a4f12d4d14fd3fcd