Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Maria, De Mieri"'
Autor:
Stefanie Zimmermann, Gerda Fouché, Maria De Mieri, Yukiko Yoshimoto, Toyonobu Usuki, Rudzani Nthambeleni, Christopher J. Parkinson, Christiaan van der Westhuyzen, Marcel Kaiser, Matthias Hamburger, Michael Adams
Publikováno v:
Molecules, Vol 19, Iss 3, Pp 3523-3538 (2014)
Sesquiterpene lactones (STLs) are natural products that have potent antitrypanosomal activity in vitro and, in the case of cynaropicrin, also reduce parasitemia in the murine model of trypanosomiasis. To explore their structure-antitrypanosomal activ
Externí odkaz:
https://doaj.org/article/a536bf42ed984b5aa61e6d9e6a520857
Autor:
Martin Smieško, AM Klemd, Ombeline Danton, Roman Huber, Carsten Gründemann, Jakob K. Reinhardt, Maria De Mieri, Thomas Bürgi, Matthias Hamburger
Publikováno v:
Journal of Natural Products, Vol. 82, No 6 (2019) pp. 1424-1433
A library of extracts from plants used in Chinese Traditional Medicine was screened for inhibition of T lymphocyte proliferation. An ethyl acetate extract from aerial parts of Artemisia argyi showed promising activity and was submitted to HPLC-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a41920d12eb6893808d1b40c8d18c4
https://doi.org/10.1021/acs.jnatprod.8b00791
https://doi.org/10.1021/acs.jnatprod.8b00791
Publikováno v:
Molecules, Vol 22, Iss 12, p 2252 (2017)
The acid-induced rearrangement of three epoxyderivatives of nobilin 1, the most abundant sesquiterpene lactone in Anthemis nobilis flowers, was investigated. From the 1,10-epoxyderivative 2, furanoheliangolide 5 was obtained, while the 4,5-epoxy grou
Externí odkaz:
https://doaj.org/article/b7405d3614be459182f9730128fae4df
Publikováno v:
Food and Chemical Toxicology. 120:155-163
The adaptation of solid tumors to the low oxygen/nutrient environment is mediated by the pivotal transcription role of hypoxia-inducible factor-1 (HIF-1). Thus, the HIF-1 and its subunits have been considered to be hopeful anti-cancer targets. Variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae4044c93cdd90eb3d04428ffc34be0
https://doi.org/10.1016/j.fct.2018.06.060
https://doi.org/10.1016/j.fct.2018.06.060
Autor:
Mahdi Moridi Farimani, Matthias Hamburger, Abbas Aliabadi, Maria De Mieri, Marcel Kaiser, Hanzaleh Moradi, Samad Nejad Ebrahimi, Bahareh Khodaei
Publikováno v:
Journal of Natural Products. 81:1384-1390
Phytochemical investigation of the lipophilic extract of the roots of Salvia leriifolia resulted in the isolation of the new rearranged abietane diterpenoids leriifoliol (1) and leriifolione (2), together with 10 known diterpenoids. Structure elucida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa288d13bd62a31a8305843d3bd7341
https://doi.org/10.1021/acs.jnatprod.7b01019
https://doi.org/10.1021/acs.jnatprod.7b01019
Publikováno v:
Journal of Natural Products. 80:2953-2961
Plant pollens are strong airborne elicitors of asthma. Their proteinaceous allergens have been studied intensively, but little is known about a possible contribution of pollen secondary metabolites to the nonallergic exacerbation of asthma. Pollen sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8e9dde16b8bb05cbbf0eb42237ded2
https://doi.org/10.1021/acs.jnatprod.7b00495
https://doi.org/10.1021/acs.jnatprod.7b00495
Publikováno v:
Phytochemistry. 138:134-144
Phytochemical profiling of Ziziphus spina-christi leaves led to the characterization of 10 dammarane-type saponins and 12 phenolic compounds. Isolation was achieved by gel chromatography on Sephadex LH20, open column chromatography on silica gel, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc57bc3e52cb0ea06de7b888903c7094
https://doi.org/10.1016/j.phytochem.2017.02.028
https://doi.org/10.1016/j.phytochem.2017.02.028
Autor:
Peyman Salehi, Markus Neuburger, Mahdi Moridi Farimani, Maria De Mieri, Sahar Mofidi Tabatabaei, Matthias Hamburger, Samad Nejad-Ebrahimi
Publikováno v:
Natural Product Research. 31:1758-1765
Phytochemical investigation of n-hexane extract of Salvia sahendica by normal phase column chromatography resulted in the isolation of six compounds. Structures were established by 1D and 2D NMR spectroscopy, and HRMS, as a new norditerpene 1, and kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e4b5e78ac6cb60e5e3ee2d54fb724f
https://doi.org/10.1080/14786419.2017.1290619
https://doi.org/10.1080/14786419.2017.1290619
Publikováno v:
Journal of Natural Products. 80:459-470
A dichlomethane extract of Anthemis nobilis flower cones showed promising in vitro antiprotozoal activity against Trypanosoma brucei rhodesiense and Leishmania donovani, with IC50 values of 1.43 ± 0.50 and 1.40 ± 0.07 μg/mL, respectively. A compre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e93d8f17a9aee0995f209aa2e4e159
https://doi.org/10.1021/acs.jnatprod.6b00980
https://doi.org/10.1021/acs.jnatprod.6b00980
Publikováno v:
Natural product communications. 11(7)
ourteen secondary metabolites, including a new secoiridoid glucoside (1), were isolated from the aerial parts of Scabiosa licida by a combination of column hromatography, preparative and semi-preparative HPLC. They were identified by extensive NMR, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e62d497519ecebeb5cc8cfaa38c879ab
https://pubmed.ncbi.nlm.nih.gov/30452154
https://pubmed.ncbi.nlm.nih.gov/30452154