Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mari Toppinen"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The long-term impact of viruses residing in the human bone marrow (BM) remains unexplored. However, chronic inflammatory processes driven by single or multiple viruses could significantly alter hematopoiesis and immune function. We performed a system
Externí odkaz:
https://doaj.org/article/3eb9ad6328744444954f2153be1a25c8
Autor:
Man Xu, Maria Fernanda Perdomo, Salla Mattola, Lari Pyöriä, Mari Toppinen, Jianming Qiu, Maija Vihinen-Ranta, Klaus Hedman, Johanna Nokso-Koivisto, Leena-Maija Aaltonen, Maria Söderlund-Venermo
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Human bocavirus 1 (HBoV1), a common pediatric respiratory pathogen, can persist in airway secretions for months hampering diagnosis. It also persists in tonsils, providing potential reservoirs for airway shedding, with the exact location, host cell t
Externí odkaz:
https://doaj.org/article/fe108de5e10844ae9182f0124f92a550
HERQ-9 Is a New Multiplex PCR for Differentiation and Quantification of All Nine Human Herpesviruses
Autor:
Lari Pyöriä, Maija Jokinen, Mari Toppinen, Henri Salminen, Tytti Vuorinen, Veijo Hukkanen, Constanze Schmotz, Endrit Elbasani, Päivi M. Ojala, Klaus Hedman, Hannamari Välimaa, Maria F. Perdomo
Publikováno v:
mSphere, Vol 5, Iss 3 (2020)
ABSTRACT Infections with the nine human herpesviruses (HHVs) are globally prevalent and characterized by lifelong persistence. Reactivations can potentially manifest as life-threatening conditions for which the demonstration of viral DNA is essential
Externí odkaz:
https://doaj.org/article/a6c28107b8b94c3c8fc20a1839e4bf27
Autor:
Mohammadreza Sadeghi, Yilin Wang, Torbjörn Ramqvist, Leena-Maija Aaltonen, Lari Pyöriä, Mari Toppinen, Maria Söderlund-Venermo, Klaus Hedman
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background In the past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of molecular methods. Serology data suggest that infections with human polyomavir
Externí odkaz:
https://doaj.org/article/13f7ad2f06d0401999a1e8f1d77bf0ce
Autor:
Lari Pyöriä, Mari Toppinen, Elina Mäntylä, Lea Hedman, Leena-Maija Aaltonen, Maija Vihinen-Ranta, Taru Ilmarinen, Maria Söderlund-Venermo, Klaus Hedman, Maria F. Perdomo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The cell type that hosts parvovirus B19 (B19V) DNA lifelong is currently unknown. Here, the authors identify tonsillar B cells as a reservoir, detect an extinct B19V type in older adults, supporting a long-term association, and show that B19V uptake
Externí odkaz:
https://doaj.org/article/c361ff35670e4ffbbdd991ab4dfb34ac
Background Little is known on the landscape of viruses that have taken residence within our cells, nor on the interplay with the host imperative for their persistence. However, a lifetime of interactions conceivably have an imprint on our physiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c86ac50704051a02f14a86466d7ec79
https://doi.org/10.21203/rs.3.rs-1465411/v2
https://doi.org/10.21203/rs.3.rs-1465411/v2
Publikováno v:
research@ua; Vol 11 (2020); 55
research@ua; vol. 11 (2020); 55
GigaScience
research@ua; vol. 11 (2020); 55
GigaScience
Background Advances in sequencing technologies have enabled the characterization of multiple microbial and host genomes, opening new frontiers of knowledge while kindling novel applications and research perspectives. Among these is the investigation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50e9420f506c6567172c23bbaff991b
https://proa.ua.pt/index.php/researchua/article/view/25644
https://proa.ua.pt/index.php/researchua/article/view/25644
Autor:
Mari Toppinen
Publikováno v:
University of Helsinki
Some viruses can establish life-long persistence in their hosts after primary infection. The main aims of this thesis were to investigate the persistence, molecular epidemiology, and evolution of human parvovirus B19 (B19V). B19V is a small single-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b146df7da1013e6509c8f043cc7df30a
http://hdl.handle.net/10138/324787
http://hdl.handle.net/10138/324787
HERQ-9 Is a New Multiplex PCR for Differentiation and Quantification of All Nine Human Herpesviruses
Autor:
Constanze Schmotz, Päivi M. Ojala, Klaus Hedman, Henri Salminen, Lari Pyöriä, Hannamari Välimaa, Mari Toppinen, Tytti Vuorinen, Veijo Hukkanen, Maria F. Perdomo, Maija Jokinen, Endrit Elbasani
Publikováno v:
mSphere, Vol 5, Iss 3, p e00265-20 (2020)
mSphere
mSphere, Vol 5, Iss 3 (2020)
mSphere
mSphere, Vol 5, Iss 3 (2020)
By adulthood, almost all humans become infected by at least one herpesvirus (HHV). The maladies inflicted by these microbes extend beyond the initial infection, as they remain inside our cells for life and can reactivate, causing severe diseases. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26520e4a9c907ada46cbb0b3e8268cf5
https://doaj.org/article/fdb7733d6557474b8f54068eafd89715
https://doaj.org/article/fdb7733d6557474b8f54068eafd89715
Autor:
Maria F. Perdomo, Diogo Pratas, Klaus Hedman, Mari Toppinen, Antti Sajantila, Elina Väisänen, Maria Söderlund-Venermo
Publikováno v:
Forensic science international. Genetics. 48
The imprints left by persistent DNA viruses in the tissues can testify to the changes driving virus evolution as well as provide clues on the provenance of modern and ancient humans. However, the history hidden in skeletal remains is practically unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901fdf2134cff43429ec1f78f842d547
https://pubmed.ncbi.nlm.nih.gov/32668397
https://pubmed.ncbi.nlm.nih.gov/32668397