Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Mari T Kaartinen"'
Autor:
Mahdokht Mahmoodi, Elahe Mirzarazi Dahagi, Mir‐Hamed Nabavi, Ylauna C. M. Penalva, Amrita Gosaine, Monzur Murshed, Sandrine Couldwell, Lisa M. Munter, Mari T. Kaartinen
Publikováno v:
Physiological Reports, Vol 12, Iss 14, Pp n/a-n/a (2024)
Abstract Plasma fibronectin (pFN) is a hepatocyte‐derived circulating extracellular matrix protein that affects cell morphology, adipogenesis, and insulin signaling of adipocytes in vitro. In this study, we show pFN accrual to adipose tissue and it
Externí odkaz:
https://doaj.org/article/98eab24d4b3746e0a419bb46aede5a2e
Autor:
Hadil F Al-Jallad, Vamsee D Myneni, Sarah A Piercy-Kotb, Nicolas Chabot, Amina Mulani, Jeffrey W Keillor, Mari T Kaartinen
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15893 (2011)
Transglutaminase activity, arising potentially from transglutaminase 2 (TG2) and Factor XIIIA (FXIIIA), has been linked to osteoblast differentiation where it is required for type I collagen and fibronectin matrix deposition. In this study we have us
Externí odkaz:
https://doaj.org/article/391e9309bc0b4d7599052a630beb9019
Publikováno v:
Cells, Vol 12, Iss 17, p 2139 (2023)
Osteoclasts are multinucleated, bone-resorbing giant cells derived from monocyte–macrophage cell lines. Increased bone resorption results in loss of bone mass and osteoporosis. Osteoclast and bone marrow macrophages have been shown to express three
Externí odkaz:
https://doaj.org/article/bd4914b6f84c440b943f6681db5d7240
Autor:
Iida Jääskeläinen, Tiina Petäistö, Elahe Mirzarazi Dahagi, Mahdokht Mahmoodi, Taina Pihlajaniemi, Mari T. Kaartinen, Ritva Heljasvaara
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1412 (2023)
The globally increasing prevalence of obesity is associated with the development of metabolic diseases such as type 2 diabetes, dyslipidemia, and fatty liver. Excess adipose tissue (AT) often leads to its malfunction and to a systemic metabolic dysfu
Externí odkaz:
https://doaj.org/article/8def20d19ee748549177ab050ddad63a
Autor:
Eric W. J. Gates, Kian Mansour, Sahar Ebrahimi Samani, Sammir Shad, Mari T. Kaartinen, Jeffrey W. Keillor
Publikováno v:
Molecules, Vol 28, Iss 4, p 1634 (2023)
Factor XIIIa (FXIIIa) is a transglutaminase of major therapeutic interest for the development of anticoagulants due to its essential role in the blood coagulation cascade. While numerous FXIIIa inhibitors have been reported, they failed to reach clin
Externí odkaz:
https://doaj.org/article/e92054fde8f9454ab0c53c53e73e74ef
Autor:
Kirsi H. Pietiläinen, Antti Hakkarainen, A. Barry, Jesper Lundbom, Aila Rissanen, Jaakko Kaprio, Mari T. Kaartinen, M. Arora, Seppo Heinonen, A. Hang, N. Lundholm
Publikováno v:
International Journal of Obesity. 45:577-587
Objective F13A1/FXIII-A transglutaminase has been linked to adipogenesis in cells and to obesity in humans and mice, however, its role and associated molecular pathways in human acquired excess weight have not been explored. Methods We examined F13A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b48f1d3e40761658a69d039f2449c36
https://doi.org/10.1038/s41366-020-00722-0
https://doi.org/10.1038/s41366-020-00722-0
Autor:
Naser Muja, Mari T. Kaartinen, Florencia Chicatun, Showan N. Nazhat, Ehsan Rezabeigi, Marc D. McKee
Publikováno v:
Emergent Materials. 2:245-262
Osteochondral tissue engineering (OTE) for joint reconstruction ideally requires a scaffold system that provides both the articular cartilage and the underlying, supportive subchondral bone. In this study, to mimic the osteochondral arrangement of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec47bbf0d4b6f84604149b4fc45d2521
https://doi.org/10.1007/s42247-019-00044-6
https://doi.org/10.1007/s42247-019-00044-6
Autor:
Marie Lordkipanidzé, Rania Rodan, Jose Luis Ramirez-GarciaLuna, Faleh Tamimi, Nasser Al-Shahrani, Faez Saleh Al-Hamed, Mari T. Kaartinen, Zahi Badran, Simon D. Tran, Osama A Elkashty
Publikováno v:
Injury. 52(7)
Objectives Age-related changes in blood composition have been found to affect overall health. Thus, this study aimed to understand the effect of these changes on bone healing by assessing how plasma derived from young and old rats affect bone healing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bbe96e1ac44f246677cba8cb96d952
https://pubmed.ncbi.nlm.nih.gov/34049703
https://pubmed.ncbi.nlm.nih.gov/34049703
Autor:
Mari T. Kaartinen, Anny Hang, Amadou Barry, Mansi Arora, Sini Heinonen, Jesper Lundbom, Antti Hakkarainen, Nina Lundholm, Aila Rissanen, Jaakko Kaprio, Kirsi H. Pietiläinen
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology. 108
Adipose tissue is a central regulator of metabolic health and its failure in obesity is a major cause of weight associated comorbidities, such as type 2 diabetes. Many extracellular matrix proteins, represented by matrisome, play a critical role in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e325c0c17e3677a89618588f6c1e11d
https://pubmed.ncbi.nlm.nih.gov/35227930
https://pubmed.ncbi.nlm.nih.gov/35227930
Autor:
Sini Heinonen, Mari T. Kaartinen, Jaakko Kaprio, Mansi Arora, Aila Rissanen, Kirsi H. Pietiläinen
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8289, p 8289 (2020)
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8289, p 8289 (2020)
Transglutaminases TG2 and FXIII-A have recently been linked to adipose tissue biology and obesity, however, human studies for TG family members in adipocytes have not been conducted. In this study, we investigated the association of TGM family member
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf51e04e35de5da58af7203e0f01ee9