Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mari Oksman"'
Autor:
Leonid Yavich, Mari Oksman, Heikki Tanila, Petri Kerokoski, Mikko Hiltunen, Thomas van Groen, Jukka Puoliväli, Pekka T. Männistö, Arturo García-Horsman, Ewen MacDonald, Konrad Beyreuther, Tobias Hartmann, Pekka Jäkälä
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 2, Pp 303-313 (2005)
We have generated a transgenic mouse line overexpressing mutated human A30P α-synuclein under the control of the prion-related protein promoter. Immunohistology revealed mutated human A30P α-synuclein protein in numerous brain areas, but no gross m
Externí odkaz:
https://doaj.org/article/cfe6ff5d05a7497399ad277a7d3f402a
Publikováno v:
Neuropharmacology. 56:647-652
Transgenic mice carrying human A30P mutated α-synuclein demonstrate hypolocomotion and dysfunction of the presynaptic machinery of dopamine overflow, induced by reducing capacity of the dopamine storage pool. We suggested that overexpression of α-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09353580a30e2bba8ee1ad8f2df1e58d
https://doi.org/10.1016/j.neuropharm.2008.11.004
https://doi.org/10.1016/j.neuropharm.2008.11.004
Autor:
Pavel Michal, Vladimír Doležal, Jan Jakubík, Heikki Tanila, Mari Oksman, Hennariikka Iivonen, Eva Machová
Publikováno v:
Neurobiology of Aging. 29:368-378
We assessed the integrity of cholinergic neurotransmission in parietal cortex of young adult (7 months) and aged (17 months) transgenic APPswe/PS1dE9 female mice compared to littermate controls. Choline acetyltransferase and acetylcholinesterase acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919ba3aa320a9051b87a931cc5a9e1ea
https://doi.org/10.1016/j.neurobiolaging.2006.10.029
https://doi.org/10.1016/j.neurobiolaging.2006.10.029
Publikováno v:
Pharmacology Biochemistry and Behavior. 78:35-45
The present work addresses the role of polyamines in learning and general behavior by subjecting transgenic mice overexpressing polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT) and their syngenic littermates to neurobehavio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f45abf379ce0223b8918dc250c70ba5
https://doi.org/10.1016/j.pbb.2004.02.001
https://doi.org/10.1016/j.pbb.2004.02.001
Publikováno v:
Neuroreport. 17(11)
Alpha-synuclein has been implicated in the pathophysiology of Parkinson's disease. Recent studies revealed its role as a negative regulator of dopamine release in the nigrostriatal dopaminergic system. Alpha-synuclein may, however, play a more univer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae28169fc34e2d6a5369cfa11694df53
https://pubmed.ncbi.nlm.nih.gov/16837852
https://pubmed.ncbi.nlm.nih.gov/16837852
Autor:
H. Iivonen, I. Leenders, E. Hogyes, Heikki Tanila, Z. Amtul, Tobias Hartmann, Mari Oksman, Dieter Lütjohann, Laus M. Broersen, Botond Penke
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 3, Pp 563-572 (2006)
The present study assessed the influence of dietary lipids on accumulation of amyloid beta-peptide (Abeta) in the brain. Seven experimental diets with varying n-6/n-3-ratio, saturated and polyunsaturated fatty acid and cholesterol contents were fed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64de78f97a3c58cbe6a041a95690061
https://pubmed.ncbi.nlm.nih.gov/16765602
https://pubmed.ncbi.nlm.nih.gov/16765602
Autor:
Heikki Tanila, Arturo Garcia-Horsman, Mari Oksman, Thomas van Groen, Pekka Jäkälä, Konrad Beyreuther, Leonid Yavich, Ewen MacDonald, Pekka T. Männistö, Jukka Puoliväli, Mikko Hiltunen, Petri Kerokoski, Tobias Hartmann
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 2, Pp 303-313 (2005)
We have generated a transgenic mouse line overexpressing mutated human A30P alpha-synuclein under the control of the prion-related protein promoter. Immunohistology revealed mutated human A30P alpha-synuclein protein in numerous brain areas, but no g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113a79b2dcff46c35b890ca86d3782ec
https://pubmed.ncbi.nlm.nih.gov/16242637
https://pubmed.ncbi.nlm.nih.gov/16242637