Zobrazeno 1 - 10
of 689
pro vyhledávání: '"Mari Mino"'
Autor:
Meghan J. Mooradian, Florian J. Fintelmann, Thomas J. LaSalle, Judit Simon, Alexander Graur, Alona Muzikansky, Mari Mino-Kenudson, Sophia Shalhout, Howard L. Kaufman, Russell W. Jenkins, Donald Lawrence, Aleigha Lawless, Tatyana Sharova, Raul N. Uppot, Jacy Fang, Emily M. Blaum, Anna L. K. Gonye, Irena Gushterova, Genevieve M. Boland, Christopher Azzoli, Nir Hacohen, Moshe Sade-Feldman, Ryan J. Sullivan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Image-guided percutaneous cryoablation is an established minimally invasive oncologic treatment. We hypothesized that cryoablation may modify the immune microenvironment through direct modulation of the tumor, thereby generating an anti-tumo
Externí odkaz:
https://doaj.org/article/efad168e55d849beb3f3fc1c90d43fdb
Autor:
Jong Ho Park, Mahsa Mortaja, Heehwa G. Son, Xutu Zhao, Lauren M. Sloat, Marjan Azin, Jun Wang, Michael R. Collier, Krishna S. Tummala, Anna Mandinova, Nabeel Bardeesy, Yevgeniy R. Semenov, Mari Mino-Kenudson, Shadmehr Demehri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Chronic inflammation is a major cause of cancer worldwide. Interleukin 33 (IL-33) is a critical initiator of cancer-prone chronic inflammation; however, its induction mechanism by environmental causes of chronic inflammation is unknown. Here
Externí odkaz:
https://doaj.org/article/e2b006d3a3b94b3d96580a3db87ec074
Autor:
M. Lisa Zhang, Khalid Algarrahi, Jamie DiCarlo, Abigail Elvin-Ivey, Michael Dougan, Mari Mino-Kenudson
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 7, Pp 986-994 (2024)
Background and Aims: Typical immune checkpoint inhibitor-induced colitis (T-ICI) has significant histomorphologic overlap with inflammatory bowel disease (IBD), a distinction further complicated in ICI-treated patients with pre-existing inflammatory
Externí odkaz:
https://doaj.org/article/e7e1d278482c43fdbe934b353666a648
Autor:
Jaime L. Schneider, Khvaramze Shaverdashvili, Mari Mino-Kenudson, Subba R. Digumarthy, Andrew Do, Audrey Liu, Justin F. Gainor, Jochen K. Lennerz, Timothy F. Burns, Jessica J. Lin
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-7 (2023)
Abstract Acquired drug resistance remains a major problem across oncogene-addicted cancers. Elucidation of mechanisms of resistance can inform rational treatment strategies for patients relapsing on targeted therapies while offering insights into tum
Externí odkaz:
https://doaj.org/article/39fd463012fa4aa7af342003242f7782
Autor:
Susan Raju Paul, Ivan Valiev, Skylar E. Korek, Vladimir Zyrin, Diana Shamsutdinova, Olga Gancharova, Alexander Zaitsev, Ekaterina Nuzhdina, Diane L. Davies, Ibiayi Dagogo‐Jack, Felix Frenkel, Jessica H. Brown, Joshua M. Hess, Sarah Viet, Jason L. Petersen, Cameron D. Wright, Harald C. Ott, Hugh G. Auchincloss, Ashok Muniappan, Toshihiro Shioda, Michael Lanuti, Christel M. Davis, Erik A. Ehli, Yin P. Hung, Mari Mino‐Kenudson, Maria Tsiper, Ann E. Sluder, Patrick M. Reeves, Nikita Kotlov, Alexander Bagaev, Ravshan Ataullakhanov, Mark C. Poznansky
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 4, Pp 156-170 (2023)
Abstract Lung cancer is the leading cause of cancer‐related deaths worldwide. Surgery and chemoradiation are the standard of care in early stages of non‐small cell lung cancer (NSCLC), while immunotherapy is the standard of care in late‐stage N
Externí odkaz:
https://doaj.org/article/2fdae20227e943d885e32ad85125e390
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 9, Pp 100557- (2023)
Introduction: Guidelines recommend obtaining a computed tomography scan of the chest for the staging of pleural mesothelioma and for assessing response to treatment. Consensus is lacking regarding the necessity of serial imaging of distant extrathora
Externí odkaz:
https://doaj.org/article/0437944dbe2843fc829e9c2a1d154d1d
Autor:
Ibiayi Dagogo-Jack, MD, Ivan Valiev, MD, Nikita Kotlov, MS, Anna Belozerova, MD, Aleksandra Lopareva, MS, MD, Anna Butusova, MS, Naira Samarina, PhD, Alexandra Boyko, MS, Zhongmin Xiang, PhD, Monique Johnson, BS, Sandrine Degryse, PhD, Florence K. Keane, MD, Lecia V. Sequist, MD, Michael Lanuti, MD, Nathan Fowler, MD, Mari Mino-Kenudson, MD, Alexander Bagaev, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 7, Pp 100527- (2023)
Introduction: Relapse is common after resection of lung adenocarcinoma (LUAD). Features of the tumor microenvironment (TME) which influence postsurgical survival outcomes are poorly characterized. Here, we analyzed the TME of more than 1500 LUAD spec
Externí odkaz:
https://doaj.org/article/acbc54d5c39b41eeb5768d2ee56dbc4c
Autor:
Mary C. Boulanger, MD, Jennifer S. Temel, MD, Mari Mino-Kenudson, MD, Lauren L. Ritterhouse, MD, PhD, Ibiayi Dagogo-Jack, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 4, Pp 100501- (2023)
The NTRK genes encode the TRK proteins. NTRK fusions lead to constitutively active, ligand-independent downstream signaling. NTRK fusions are implicated in up to 1% of all solid tumors and 0.2% of NSCLC. Larotrectinib, a highly selective small molecu
Externí odkaz:
https://doaj.org/article/4f543e45c5e04d4c99b768fed1a7106e
Autor:
Alissa J. Cooper, MD, Alona Muzikansky, MA, Jochen Lennerz, MD, PhD, Farhaana Narinesingh, M.B.B.S., Mari Mino-Kenudson, MD, Yin P. Hung, MD, PhD, Zofia Piotrowska, MD, MHS, Ibiayi Dagogo-Jack, MD, Lecia V. Sequist, MD, MPH, Justin F. Gainor, MD, Jessica J. Lin, MD, Rebecca S. Heist, MD, MPH
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 9, Pp 100390- (2022)
Introduction: Co-occurring mutations in KRAS-mutant NSCLC are associated with discrete biological properties and modulate therapeutic susceptibilities. As G12D-specific inhibitors are expected to enter the clinic, we sought to investigate the charact
Externí odkaz:
https://doaj.org/article/b74d2bef942c4556b6ea5685e2ff735a
Autor:
Girgis Obaid, Shazia Bano, Hanna Thomsen, Susan Callaghan, Nimit Shah, Joseph W. R. Swain, Wendong Jin, Xiadong Ding, Colin G. Cameron, Sherri A. McFarland, Juwell Wu, Mark Vangel, Svetla Stoilova‐McPhie, Jie Zhao, Mari Mino‐Kenudson, Charles Lin, Tayyaba Hasan
Publikováno v:
Advanced Science, Vol 9, Iss 24, Pp n/a-n/a (2022)
Abstract Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits 5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that contribute to treatment resistance, yet depleting the stroma
Externí odkaz:
https://doaj.org/article/0670866fd506442c8ba84eb912ca8dbe