Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mari Komita"'
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Background: Most neurodegenerative diseases are sporadic and develop with age. Degenerative neural tissues often contain intra- and extracellular protein aggregates, suggesting that the proteostasis network that combats protein misfolding could be dy
Externí odkaz:
https://doaj.org/article/905942b459dd4608b0cb7814017beca1
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Protein quality control in the early secretory pathway is a ubiquitous eukaryotic mechanism for adaptation to endoplasmic reticulum (ER) stress. An ER molecular chaperone, immunoglobulin heavy chain-binding protein (BiP), is one of the essential comp
Externí odkaz:
https://doaj.org/article/ce9a1ed5a5c448fa945c00b6880ba9a2
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 2
International Journal of Molecular Sciences, Vol 21, Iss 2, p 450 (2020)
Volume 21
Issue 2
International Journal of Molecular Sciences, Vol 21, Iss 2, p 450 (2020)
Preclinical studies have shown that exposure of the developing brain to inhalational anesthetics can cause neurotoxicity. However, other studies have claimed that anesthetics can exert neuroprotective effects. We investigated the mechanisms associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c192cd2ece15de23b81b178b0165ef
https://doi.org/10.3390/ijms21020450
https://doi.org/10.3390/ijms21020450
Publikováno v:
International Journal of Molecular Sciences; 1/15/2020, Vol. 21 Issue 2, p1-14, 14p, 1 Diagram, 3 Graphs
Publikováno v:
Anesthesia & Analgesia. 117:1197-1204
The mechanisms by which inhaled anesthetics cause neurotoxicity are not well clarified. Exposure to inhaled anesthetics induces a release of Ca from the endoplasmic reticulum (ER) into the cytosol. Aberrant Ca mobilization may alter the protein-foldi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153fc6fcb270a7f4bbd1159c2d37e37d
https://doi.org/10.1213/ane.0b013e3182a74773
https://doi.org/10.1213/ane.0b013e3182a74773
Publikováno v:
Cell stresschaperones. 22(1)
Most human neurodegenerative diseases are sporadic and appear later in life. Aging and neurodegeneration are closely associated, and recent investigations reveal that endoplasmic reticulum (ER) stress is involved in the progression of these features.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d036bffb01598b15272d10b298ebf2
https://pubmed.ncbi.nlm.nih.gov/27796797
https://pubmed.ncbi.nlm.nih.gov/27796797