Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Mari Ishigami-Yuasa"'
Autor:
Manami Kodaka, Fengju Mao, Kyoko Arimoto-Matsuzaki, Masami Kitamura, Xiaoyin Xu, Zeyu Yang, Kentaro Nakagawa, Junichi Maruyama, Kana Ishii, Chihiro Akazawa, Takuya Oyaizu, Naoki Yamamoto, Mari Ishigami-Yuasa, Nozomi Tsuemoto, Shigeru Ito, Hiroyuki Kagechika, Hiroshi Nishina, Yutaka Hata
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231265 (2020)
Transcriptional co-activator with PDZ-binding motif (TAZ) plays versatile roles in the regulation of cell proliferation and differentiation. TAZ activity changes in response to the cellular environment such as mechanic and nutritional stimuli, osmola
Externí odkaz:
https://doaj.org/article/b70078fd67084d0c9c9d320b3df09460
Autor:
Yuki Yoshizaki, Takayasu Mori, Mari Ishigami-Yuasa, Eriko Kikuchi, Daiei Takahashi, Moko Zeniya, Naohiro Nomura, Yutaro Mori, Yuya Araki, Fumiaki Ando, Shintaro Mandai, Yuri Kasagi, Yohei Arai, Emi Sasaki, Sayaka Yoshida, Hiroyuki Kagechika, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The Kelch-like ECH-associating protein 1 (Keap1)-nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) signaling pathway is the major regulator of cytoprotective responses to oxidative and electrophilic stress
Externí odkaz:
https://doaj.org/article/9033bda222a94a88a5557b6bef9e8da0
Autor:
Hitomi Koga, Mai Negishi, Marie Kinoshita, Shinya Fujii, Shuichi Mori, Mari Ishigami-Yuasa, Emiko Kawachi, Hiroyuki Kagechika, Aya Tanatani
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5584 (2020)
First-generation nonsteroidal androgen receptor (AR) antagonists, such as flutamide (2a) and bicalutamide (3), are effective for most prostate cancer patients, but resistance often appears after several years due to the mutation of AR. Second-generat
Externí odkaz:
https://doaj.org/article/3653ad704cb7441cbbf2894ba085db39
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5512 (2020)
Nuclear receptors are ligand-inducible transcriptional factors that control multiple biological phenomena, including proliferation, differentiation, reproduction, metabolism, and the maintenance of homeostasis. Members of the nuclear receptor superfa
Externí odkaz:
https://doaj.org/article/950f7a8d0d1e4d16b704b97edf9064ac
Autor:
Ruoxing Yu, Norio Miyamura, Yoshimi Okamoto-Uchida, Norie Arima, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Hiroshi Nishina
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145286 (2015)
Mammalian fetal development is easily disrupted by exogenous agents, making it essential to test new drug candidates for embryotoxicity and teratogenicity. To standardize the testing of drugs that might be used to treat pregnant women, the U.S. Food
Externí odkaz:
https://doaj.org/article/3ea6df851f5a4e299bea6548046823c1
Autor:
Yutaka Hata, Kouhei Yamamoto, Daichi Nogawa, Hiroshi Nishina, Jun Hirayama, Norio Miyamura, Hiroyuki Kagechika, Mari Ishigami-Yuasa, Kentaro Nakagawa, Hiroaki Iwasa, Xinliang Jiang, Fumiyoshi Michishita, Kazutoshi Inami, Junichi Maruyama
Yes-associated protein 1 (YAP1) interacts with numerous transcription factors, including TEA-domain family proteins (TEAD) and p73. YAP1 is negatively regulated by the tumor suppressor Hippo pathway. In human cancers, the deregulation of the Hippo pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0629eb868bc6c4f437c0cddfc760299c
https://doi.org/10.1158/1541-7786.c.6540226.v1
https://doi.org/10.1158/1541-7786.c.6540226.v1
Autor:
Yutaka Hata, Kouhei Yamamoto, Daichi Nogawa, Hiroshi Nishina, Jun Hirayama, Norio Miyamura, Hiroyuki Kagechika, Mari Ishigami-Yuasa, Kentaro Nakagawa, Hiroaki Iwasa, Xinliang Jiang, Fumiyoshi Michishita, Kazutoshi Inami, Junichi Maruyama
Supplementary Figures 1 - 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72be4d602f157f388087384329931d98
https://doi.org/10.1158/1541-7786.22512376
https://doi.org/10.1158/1541-7786.22512376
Autor:
Mari Ishigami-Yuasa, Tetsuro Watabe, Hiroyuki Harada, Rina Takayama, Hiroyuki Kagechika, Kazuki Takahashi, Katarzyna A. Podyma-Inoue, Shintaro Sakakitani
Publikováno v:
Cancer Science
Metastasis is a primary reason related to the mortality of oral squamous cell carcinoma (OSCC) patients. A program called epithelial‐mesenchymal transition (EMT) has been shown to play a critical role in promoting metastasis in epithelium‐derived
Autor:
Hiroyuki Kagechika, Mari Ishigami-Yuasa, Shuji Terai, Erika Ishihara, Yasuyuki Fujita, Akira Suzuki, Satoshi Kofuji, Takehiko Yokomizo, Hiroshi Nishina, Toshiaki Okuno, Yukihiko Sugimoto, Yuya Nagaoka, Kenya Kamimura
Publikováno v:
Genes to Cells. 25(3):197-214
Cell competition is a biological process by which unfit cells are eliminated from "cell society." We previously showed that cultured mammalian epithelial Madin-Darby canine kidney (MDCK) cells expressing constitutively active YAP were eliminated by a
Autor:
Takashi Sakurai, Nagomi Kurebayashi, Takashi Murayama, Noriaki Manaka, Hiroto Iinuma, Ryota Arai, Yoshiaki Nishijima, Shuichi Mori, Akiko Sakurai, Hiroyuki Kagechika, Mari Ishigami-Yuasa
Publikováno v:
European Journal of Medicinal Chemistry. 179:837-848
Type-1 ryanodine receptor (RyR1) is a calcium-release channel localized on sarcoplasmic reticulum (SR) of the skeletal muscle, and mediates muscle contraction by releasing Ca2+ from the SR. Genetic mutations of RyR1 are associated with skeletal muscl