Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Mari ISHIDA"'
Autor:
Chiemi Sakai, Keitaro Ueda, Kohei Goda, Rikuto Fujita, Junji Maeda, Shinya Nakayama, Yusuke Sotomaru, Satoshi Tashiro, Masao Yoshizumi, Takafumi Ishida, Mari Ishida
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract DNA damage contributes to atherosclerosis. However, causative links between DNA double-strand breaks (DSBs) and atherosclerosis have yet to be established. Here, we investigated the role of DSBs in atherosclerosis using mice and vascular cel
Externí odkaz:
https://doaj.org/article/d8c4cafcb3054391af75ade783ca942c
Autor:
Kohei Karasaki, Hiroki Kokubo, Batmunkh Bumdelger, Nobuchika Kaji, Chiemi Sakai, Mari Ishida, Masao Yoshizumi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 3 (2023)
Background Angiotensin II type 1 receptor blockers (ARBs) have been shown to limit the growth of abdominal aortic aneurysm (AAA), but their efficacy is controversial. This study aimed to investigate the molecular mechanism underlying the protective e
Externí odkaz:
https://doaj.org/article/69fc987909204bc78c6c2aefbedd3d19
Autor:
Satomi Miki, Jun-ichiro Suzuki, Miyuki Takashima, Mari Ishida, Hiroki Kokubo, Masao Yoshizumi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Atherosclerosis is a chronic inflammatory disease that may lead to the development of serious cardiovascular diseases. Aged garlic extract (AGE) has been reported to ameliorate atherosclerosis, although its mode of action remains unclear. We
Externí odkaz:
https://doaj.org/article/021dfad5244f4d6cab3bb0b09c4f73c9
Autor:
Wenyu Hu, Anqi Dong, Kohei Karasaki, Shota Sogabe, Daiki Okamoto, Masato Saigo, Mari Ishida, Masao Yoshizumi, Hiroki Kokubo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Bmp plays an important role in cardiomyocyte differentiation, but the function of Smad4 in Bmp signaling remains elusive. Here, we show that disruption of the Smad4 gene in cardiac progenitors expressing Sfrp5 led to embryonic lethality with
Externí odkaz:
https://doaj.org/article/facdf754252742c58ba07118dc45ac9e
Autor:
Takatoshi Kakuta, Kaichiro Sawada, Genta Kanai, Ryoko Tatsumi, Takayo Miyakogawa, Mari Ishida, Raima Nakazawa, Masafumi Fukagawa
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Possible ectopic parathyroid hormone (PTH) production in adipose tissues surrounding hyperplastic parathyroid glands was examined in patients with secondary hyperparathyroidism (SHPT). In vitro culture of adipose tissues from 31 patients exc
Externí odkaz:
https://doaj.org/article/0b286d0d26094816af21af801472a8e2
Autor:
Batmunkh Bumdelger, Mikage Otani, Kohei Karasaki, Chiemi Sakai, Mari Ishida, Hiroki Kokubo, Masao Yoshizumi
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235553 (2020)
Aortic aneurysm refers to dilatation of the aorta due to loss of elasticity and degenerative weakening of its wall. A preventive role for osteoprotegerin (Opg) in the development of abdominal aortic aneurysm has been reported in the CaCl2-induced ane
Externí odkaz:
https://doaj.org/article/4bd1a37817e74921998e426e34d7bef6
Autor:
Chiemi Sakai, Mari Ishida, Hideo Ohba, Hiromitsu Yamashita, Hitomi Uchida, Masao Yoshizumi, Takafumi Ishida
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187934 (2017)
Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), likely prevent cardiovascular disease, however their mechanisms remain unclear. Recently, the role of DNA damage in atherogenesis has been receiving conside
Externí odkaz:
https://doaj.org/article/9671edc84a854c4f991990b0bfae9013
Autor:
Batmunkh Bumdelger, Hiroki Kokubo, Ryo Kamata, Masayuki Fujii, Koichi Yoshimura, Hiroki Aoki, Yuichi Orita, Takafumi Ishida, Megu Ohtaki, Masataka Nagao, Mari Ishida, Masao Yoshizumi
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147088 (2016)
Abdominal aortic aneurysms (AAAs), which commonly occur among elderly individuals, are accompanied by a risk of rupture and subsequent high mortality. Establishment of medical therapies for the prevention of AAAs requires further understanding of the
Externí odkaz:
https://doaj.org/article/e2e9733a197e45c680c155f398e905b9
Autor:
Ryo Kamata, Batmunkh Bumdelger, Hiroki Kokubo, Masayuki Fujii, Koichi Yoshimura, Takafumi Ishida, Mari Ishida, Masao Yoshizumi
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165132 (2016)
Abdominal aortic aneurysms (AAAs), which commonly occur among elderly individuals, are accompanied by a risk of rupture with a high mortality rate. Although eicosapentaenoic acid (EPA) has been reported to prevent AAA formation, the mechanism by whic
Externí odkaz:
https://doaj.org/article/9753dbb6f384486bb09fcb9c2619985a
Autor:
Mari Ishida, Takafumi Ishida, Satoshi Tashiro, Hitomi Uchida, Chiemi Sakai, Naoya Hironobe, Katsuya Miura, Yu Hashimoto, Koji Arihiro, Kazuaki Chayama, Yasuki Kihara, Masao Yoshizumi
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103993 (2014)
OBJECTIVE:Cigarette smoking is a major risk factor for atherosclerotic cardiovascular disease, which is responsible for a significant proportion of smoking-related deaths. However, the precise mechanism whereby smoking induces this pathology has not
Externí odkaz:
https://doaj.org/article/214fc7bada3747faa5c853d9d1dbb09c