Výsledky vyhledávání - "Mari A, Virtanen"

Akademický článek

Acute neuroinflammation leads to disruption of neuronal chloride regulation and consequent hyperexcitability in the dentate gyrus

Autor: Samu N. Kurki, Rakenduvadhana Srinivasan, Jens Laine, Mari A. Virtanen, Tommi Ala-Kurikka, Juha Voipio, Kai Kaila

Publikováno v: Cell Reports, Vol 42, Iss 11, Pp 113379- (2023)

Summary: Neuroinflammation is a salient part of diverse neurological and psychiatric pathologies that associate with neuronal hyperexcitability, but the underlying molecular and cellular mechanisms remain to be identified. Here, we show that peripher

Externí odkaz: https://doaj.org/article/2cb6f42c02174f51a7c3c75ebee82121

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Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development

Autor: Samu N, Kurki, Pavel, Uvarov, Alexey S, Pospelov, Kalevi, Trontti, Antje K, Hübner, Rakenduvadhana, Srinivasan, Masahiko, Watanabe, Iiris, Hovatta, Christian A, Hübner, Kai, Kaila, Mari A, Virtanen

Publikováno v: Cerebral Cortex. 33:5906-5923

The Na-K-2Cl cotransporter NKCC1 is widely expressed in cells within and outside the brain. However, our understanding of its roles in brain functions throughout development, as well as in neuropsychiatric and neurological disorders, has been severel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1675d7539bde8f0051e5a421a767a3
https://doi.org/10.1093/cercor/bhac470

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Akademický článek

NKCC1, an Elusive Molecular Target in Brain Development: Making Sense of the Existing Data

Autor: Mari A. Virtanen, Pavel Uvarov, Christian A. Hübner, Kai Kaila

Publikováno v: Cells, Vol 9, Iss 12, p 2607 (2020)

Ionotropic GABA transmission is mediated by anion (mainly Cl−)-permeable GABAA receptors (GABAARs). In immature neurons, GABA exerts depolarizing and sometimes functionally excitatory actions, based on active uptake of Cl− by the Na-K-2Cl cotrans

Externí odkaz: https://doaj.org/article/65a7c4ad69464c6891c9cbbe5bc0c8ef

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Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus

Autor: Valentin Schmutz, Nicolas Toni, Mari A. Virtanen, Lucas A. Mongiat, Jan Armida, Matteo Bergami, Laszlo Vutskits, Marine Krzisch, Fred H. Gage, Alejandro F. Schinder, Jacqueline Kocher-Braissant, Silvio Gabriel Temprana, Karl-Klaus Conzelmann, Rudolf Kraftsik

Publikováno v: Brain Structure & Function
Brain structure & function
Brain Structure and Function, vol. 220, no. 4, pp. 2027-2042
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Brain Structure and Function, Vol. 220, No 4 (2015) pp. 2027-2042

The adult dentate gyrus produces new neurons that morphologically and functionally integrate into the hippocampal network. In the adult brain, most excitatory synapses are ensheathed by astrocytic perisynaptic processes that regulate synaptic structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4ce4747eb262a82ec34c49ed41eaac
http://doc.rero.ch/record/331327/files/429_2014_Article_768.pdf

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Carbonic anhydrase seven bundles filamentous actin and regulates dendritic spine morphology and density

Autor: Mari A. Virtanen, Peter Blaesse, Eva Ruusuvuori, Ville O. Paavilainen, Pirta Hotulainen, Michael Blaesse, Enni Bertling, Laszlo Vutskits, Elena Kremneva, Milla Summanen, Inkeri Spoljaric, Patricia Seja, Kai Kaila, Gergana Gateva, Pavel Uvarov

Publikováno v: EMBO Reports

Intracellular pH is a potent modulator of neuronal functions. By catalyzing (de)hydration of CO2, intracellular carbonic anhydrase (CAi) isoforms CA2 and CA7 contribute to neuronal pH buffering and dynamics. The presence of two highly active isoforms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a46850e0bed28db4cf6d036356caaf
http://hdl.handle.net/10138/328870

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Students’ perceptions on the use of a ubiquitous 360° learning environment in histotechnology: a pilot study

Autor: Maria Kääriäinen, Eeva Liikanen, Mari A. Virtanen, Elina Haavisto

Publikováno v: Journal of Histotechnology. 41(2):1-9

This study assessed students’ perceptions of a ubiquitous 360° learning environment (ULE) in histotechnology comparing ULE perceptions to conventional web-based learning environment (WLE). Based on...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e261fa4644dd6a4f465f56dc5d2a5bb
https://doi.org/10.1080/01478885.2018.1439680

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Vasopressin excites interneurons to suppress hippocampal network activity across a broad span of brain maturity at birth

Autor: Karl Deisseroth, Jenna Lindfors, Brian Hsueh, Patricia Seja, Inkeri Spoljaric, Juha Voipio, Ailey K. Crow, Martin Puskarjov, Kai Kaila, Eva Ruusuvuori, Pavel Uvarov, Albert Spoljaric, Mari A. Virtanen, Milla Summanen

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance The transition from placental to lung-based oxygen supply at mammalian birth involves an obligatory period of asphyxia, which is further aggravated by complications during delivery. This oxygen deprivation is a major threat to the fetal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f4782c394c5c5d7b2a956c164cf3f8
http://europepmc.org/articles/PMC5740624

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Ubiquitous learning environments in higher education: A scoping literature review

Autor: Elina Haavisto, Mari A. Virtanen, Eeva Liikanen, Maria Kääriäinen

Publikováno v: Education and Information Technologies. 23:985-998

Ubiquitous learning and the use of ubiquitous learning environments heralds a new era in higher education. Ubiquitous learning environments enhance context-aware and seamless learning experiences available from any location at any time. They support

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e1a179e3df88af790931bc42ab509a4
https://doi.org/10.1007/s10639-017-9646-6

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Carbonic anhydrase VII regulates dendritic spine morphology and density via actin filament bundling

Autor: Mari A. Virtanen, Kai Kaila, Michael Blaesse, Milla Summanen, Enni Bertling, Eva Ruusuvuori, Inkeri Spoljaric, Peter Blaesse, Pirta Hotulainen, Laszlo Vutskits, Elena Kremneva, Ville O. Paavilainen, Gergana Gateva, Patricia Seja

Intracellular pH is a potent modulator of neuronal functions. By catalyzing (de)hydration of CO2, intracellular carbonic anhydrase (CAi) isoforms CAII and CAVII contribute to neuronal pH buffering and dynamics. The presence of two highly active isofo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c1d86475df5c3017d3a441ec59fe8a
https://doi.org/10.1101/736868

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The comparison of students’ satisfaction between ubiquitous and web-basedlearning environments

Autor: Elina Haavisto, Maria Kääriäinen, Mari A. Virtanen, Eeva Liikanen

Publikováno v: Education and Information Technologies. 22:2565-2581

Higher education is moving towards digitalized learning. The rapid development of technological resources, devices and wireless networks enables more flexible opportunities to study and learn in innovative learning environments. New technologies enab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ccc6532d654b7dfce16c4bc4d1c3dcdc
https://doi.org/10.1007/s10639-016-9561-2

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