Zobrazeno 1 - 10
of 50
pro vyhledávání: '"María Villa-Morales"'
Autor:
Antonio Lahera, Laura Vela-Martín, Pablo Fernández-Navarro, Pilar Llamas, José L. López-Lorenzo, Javier Cornago, Javier Santos, José Fernández-Piqueras, María Villa-Morales
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract Precursor T-cell neoplasms (T-ALL/LBL) are aggressive hematological malignancies that arise from the malignant transformation of immature thymocytes. Despite the JAK/STAT pathway is recurrently altered in these neoplasms, there are not pharm
Externí odkaz:
https://doaj.org/article/c8037d4ae28942409f7da1cc7c6cb1b9
Autor:
Isabel Tundidor, Marta Seijo-Vila, Sandra Blasco-Benito, María Rubert-Hernández, Sandra Adámez, Clara Andradas, Sara Manzano, Isabel Álvarez-López, Cristina Sarasqueta, María Villa-Morales, Carmen González-Lois, Esther Ramírez-Medina, Belén Almoguera, Antonio J. Sánchez-López, Laura Bindila, Sigrid Hamann, Norbert Arnold, Christoph Röcken, Ignacio Heras-Murillo, David Sancho, Gema Moreno-Bueno, María M. Caffarel, Manuel Guzmán, Cristina Sánchez, Eduardo Pérez-Gómez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Clinical management of breast cancer (BC) metastasis remains an unmet need as it accounts for 90% of BC-associated mortality. Although the luminal subtype, which represents >70% of BC cases, is generally associated with a favorable outcome,
Externí odkaz:
https://doaj.org/article/ab9e0b407ed94740a55b818db99ef737
Autor:
María Villa-Morales, Laura Pérez-Gómez, Eduardo Pérez-Gómez, Pilar López-Nieva, Pablo Fernández-Navarro, Javier Santos
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10350 (2023)
The standard-of-care treatment of T-cell acute lymphoblastic leukaemia (T-ALL) with chemotherapy usually achieves reasonable rates of initial complete response. However, patients who relapse or do not respond to conventional therapy show dismal outco
Externí odkaz:
https://doaj.org/article/e568ebac34244decb41903ee781a04ed
Autor:
José Luis Marín-Rubio, Laura Vela-Martín, Jack Gudgeon, Eduardo Pérez-Gómez, Frances R. Sidgwick, Matthias Trost, Debbie L. Cunningham, Javier Santos, José Fernández-Piqueras, María Villa-Morales
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15157 (2022)
A reduction in FADD levels has been reported in precursor T-cell neoplasms and other tumor types. Such reduction would impact on the ability of tumor cells to undergo apoptosis and has been associated with poor clinical outcomes. However, FADD is als
Externí odkaz:
https://doaj.org/article/a49c703d31fd4dbd8cc1600e2aaa458d
Autor:
Pilar López-Nieva, Pablo Fernández-Navarro, Concepción Vaquero-Lorenzo, María Villa-Morales, Osvaldo Graña-Castro, María Ángeles Cobos-Fernández, José Luis López-Lorenzo, Pilar Llamas, Laura González-Sanchez, Isabel Sastre, Marina Pollan, Marcos Malumbres, Javier Santos, José Fernández-Piqueras
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Precursor T-cell lymphoblastic lymphomas (T-LBL) are rare aggressive hematological malignancies that mainly develop in children. As in other cancers, the loss of cell cycle control plays a prominent role in the pathogenesis in the
Externí odkaz:
https://doaj.org/article/8c05930c4cca48cc98e127c09078321c
Autor:
Antonio Lahera, Pilar López‐Nieva, Hernán Alarcón, José L. Marín‐Rubio, María Á. Cobos‐Fernández, Pablo Fernández‐Navarro, Agustín F. Fernández, Laura Vela‐Martín, Isabel Sastre, Sara Ruiz‐García, Pilar Llamas, José L. López‐Lorenzo, Javier Cornago, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales
Publikováno v:
Scopus
Despite the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway being frequently altered in T-ALL/LBL, no specific therapy has been approved for T-ALL/LBL patients with constitutive signalling by JAK/STAT, so there is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71d0f2b00cba28da6de3f3d19757bf6
https://doi.org/10.1111/bjh.18694
https://doi.org/10.1111/bjh.18694
Autor:
Santos, María Villa-Morales, Laura Pérez-Gómez, Eduardo Pérez-Gómez, Pilar López-Nieva, Pablo Fernández-Navarro, Javier
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10350
The standard-of-care treatment of T-cell acute lymphoblastic leukaemia (T-ALL) with chemotherapy usually achieves reasonable rates of initial complete response. However, patients who relapse or do not respond to conventional therapy show dismal outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0e04ae550a5f806850fc930191639a10
Autor:
Miguel Quintanilla, Carmelo Bernabéu, Javier Dotor, Carlos Gamallo, José Fernández-Piqueras, Javier Santos, María Villa-Morales, Eduardo Pérez-Gómez
Endoglin is a membrane glycoprotein that acts as a coreceptor for transforming growth factor-β. We and others have previously suggested a function of endoglin as a tumor suppressor in epithelial cancer. Here, we study the expression of endoglin duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe6e82707f8e2b88f02d34881522f87
https://doi.org/10.1158/0008-5472.c.6495828
https://doi.org/10.1158/0008-5472.c.6495828
Autor:
Miguel Quintanilla, Carmelo Bernabéu, Javier Dotor, Carlos Gamallo, José Fernández-Piqueras, Javier Santos, María Villa-Morales, Eduardo Pérez-Gómez
Supplementary Figure 3 from A Role for Endoglin as a Suppressor of Malignancy during Mouse Skin Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5c536282391477b4a7792063c9cd29
https://doi.org/10.1158/0008-5472.22368150.v1
https://doi.org/10.1158/0008-5472.22368150.v1
Autor:
Miguel Quintanilla, Carmelo Bernabéu, Javier Dotor, Carlos Gamallo, José Fernández-Piqueras, Javier Santos, María Villa-Morales, Eduardo Pérez-Gómez
Supplementary Table 1 from A Role for Endoglin as a Suppressor of Malignancy during Mouse Skin Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b0db7ef22e185f709e7827c62244a9
https://doi.org/10.1158/0008-5472.22368144
https://doi.org/10.1158/0008-5472.22368144