Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mariëtte A. Oosterwegel"'
Autor:
Kiki Tesselaar, Peter van der Ley, Liana Steeghs, Mariëtte A. Oosterwegel, Elise H. R. Schrijver, Andries van Mourik, Miranda E.A.T. van Berkel
Publikováno v:
Vaccine. 25:4681-4688
The development of novel vaccines against Neisseria meningitidis recently gained momentum by the generation of penta-acylated lpxL1 LPS which has similar adjuvant activity, but reduced endotoxic activity as compared to hexa-acylated wild type (H44/76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e0ba6629e4f0ef4b6eae667ef4ed28
https://doi.org/10.1016/j.vaccine.2007.04.016
https://doi.org/10.1016/j.vaccine.2007.04.016
Publikováno v:
Immunology Letters. 105:115-122
Numerous studies have revealed that the B7.1/B7.2-CD28 and B7RP-1-ICOS (Inducible COStimulator) pathways provide crucial costimulatory signals to T cells. We have compared the contribution of these pathways during primary and effector responses, in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559ec8ef023fe18382e425994d5ccb43
https://doi.org/10.1016/j.imlet.2006.02.007
https://doi.org/10.1016/j.imlet.2006.02.007
Autor:
W. van Eden, Suzanne E. Berlo, F Hauet-Broere, Mariëtte A. Oosterwegel, Peter J.S. van Kooten, Chris P. M. Broeren, Corlinda ten Brink, Tibor T. Glant
Publikováno v:
Journal of Autoimmunity. 25:172-180
Proteoglycan (PG)-induced arthritis (PGIA), a murine model for rheumatoid arthritis (RA), is driven by antigen (PG)-specific T and B cell activation. In order to analyze the pathogenic role of antigen-specific T cells in the development of autoimmune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87c9a3bdfca885c5f4e7b633fb0a75b
https://doi.org/10.1016/j.jaut.2005.09.017
https://doi.org/10.1016/j.jaut.2005.09.017
Autor:
Chris P. M. Broeren, Mariëtte A. Oosterwegel, Frans M. A. Hofhuis, Anthony J. Coyle, Kiki Tesselaar, Elise H. R. Schrijver, Arlene H. Sharpe, Miranda E.A.T. van Berkel
Publikováno v:
The Journal of Immunology. 175:182-188
Both CD28 and ICOS are important costimulatory molecules that promote Ag-specific cellular and humoral immune reactions. Whereas CD28 is generally thought to be the most important molecule in the initiation of a T cell response, ICOS is considered to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c59b73990052b4086535045f0d9a47e
https://doi.org/10.4049/jimmunol.175.1.182
https://doi.org/10.4049/jimmunol.175.1.182
Autor:
Frans M. A. Hofhuis, A. J. M. Van Oosterhout, B.C.A.M. van Esch, Mariëtte A. Oosterwegel, D.T. Deurloo, Frans P. Nijkamp, M. A. T. Van Berkel
Publikováno v:
Clinical & Experimental Allergy. 33:1297-1304
Summary Background The existence of a third B7-1/B7-2 receptor was postulated in a recent study using a novel mouse strain lacking both CD28 and CTLA4 (CD28/CTLA4−/−). Objective In the present study, it was investigated if T cell co-stimulation v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6386045afeb5fdeb5d3e9643b07d2839
https://doi.org/10.1046/j.1365-2222.2003.01757.x
https://doi.org/10.1046/j.1365-2222.2003.01757.x
Autor:
Arlene H. Sharpe, Mariëtte A. Oosterwegel, Anup Kubal, Vassiliki A. Boussiotis, Diane van der Woude, Rebecca J. Greenwald, Didier A. Mandelbrot
Publikováno v:
European Journal of Immunology. 32:366-373
Engagement of CTLA-4 is critical for inhibiting T cell immune responses. Recent studies have shown that CTLA-4 plays a key role in regulating peripheral T cell tolerance. It has been suggested that one mechanism by which CTLA-4 performs this function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ee745be8988a8b699ba5da9331623c9
https://doi.org/10.1002/1521-4141(200202)32:2<366::aid-immu366>3.0.co
https://doi.org/10.1002/1521-4141(200202)32:2<366::aid-immu366>3.0.co
Publikováno v:
Immunity. 6:351-360
The embryonic thymic microenvironment provides the necessary elements for T cell lineage commitment, but the precise role of individual stromal cell components remains to be determined. Here we address the question of which stromal cell types are req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560990422ff560cc2ef600efce4138cf
https://doi.org/10.1016/s1074-7613(00)80337-4
https://doi.org/10.1016/s1074-7613(00)80337-4
Autor:
Susan Godsave, Olivier Destrée, Jeroen P. Roose, Vladimir Korinek, Miranda Molenaar, Marc van de Wetering, Josi Peterson-Maduro, Hans Clevers, Mariëtte A. Oosterwegel
Publikováno v:
Cell, 86, 391-399. Elsevier B.V.
XTcf-3 is a maternally expressed Xenopus homolog of the mammalian HMG box factors Tcf-1 and Lef-1. The N-terminus of XTcf-3 binds to beta-catenin. Microinjection of XTcf-3 mRNA in embryos results in nuclear translocation of beta-catenin. The beta-cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6c56f4f47d07f384084ec27302c8dc
Autor:
Ada M. Kruisbeek, Mariëtte A. Oosterwegel, Hans Clevers, F. Meijlink, M van de Wetering, J. Timmerman, Olivier Destrée
Publikováno v:
Development. 118:439-448
The recent identification of a number of T lymphocytespecific enhancers has allowed the cloning of several novel transcription factors. Two of these, TCF-1 and LEF-1, contain a virtually identical DNA-binding domain of the High Mobility Group (HMG-1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062f91618a2ee14a50b71ff3045b62d5
https://doi.org/10.1242/dev.118.2.439
https://doi.org/10.1242/dev.118.2.439
The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization
Autor:
Hans Clevers, A H Geurts van Kessel, R.F. Suijkerbuijk, M van de Wetering, Frank C. P. Holstege, Mariëtte A. Oosterwegel, D Dooyes
Publikováno v:
Journal of Biological Chemistry. 267:8530-8536
We have recently isolated cDNA clones representing four alternative splice forms of a T cell-specific transcription factor, TCF-1. Here we report the characterization of the human gene encoding this factor. The TCF-1 gene is contained in 10 exons inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3b34cf48a5a9991bbe1d579b9cd142a
https://doi.org/10.1016/s0021-9258(18)42476-3
https://doi.org/10.1016/s0021-9258(18)42476-3