Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mariëlle J. Tempelman"'
Autor:
Rianne C. Scholman, Sanne Hiddingh, Beatriz Malvar Fernandez, Wilco de Jager, Barbara Giovannone, Mariëlle J. Tempelman, Jenny Meerding, Berent J. Prakken, Mariska E. A. van Dijk
Publikováno v:
Cytokine. 106
Diagnosis of complex disease and response to treatment is often associated with multiple indicators, both clinical and laboratorial. With the use of biomarkers, various mechanisms have been unraveled which can lead to better and faster diagnosis, pre
Autor:
Yvonne T. van der Schouw, Diederick E. Grobbee, Mark Roest, Mariëlle J. Tempelman, Philip G. de Groot, Jan J. Sixma, Jan Dirk Banga
Publikováno v:
American Journal of Epidemiology. 153:673-679
Methylenetetrahydrofolate reductase (MTHFR) is involved in the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. A 677 C/T single nucleotide polymorphism localized in the MTHFR gene is associated with both thermolability and re
Autor:
Yvonne T. van der Schouw, Diederick E. Grobbee, Jan J. Sixma, Philip G. de Groot, Jan Dirk Banga, Mark Roest, Mariëlle J. Tempelman
Publikováno v:
Circulation. 101:67-70
Background —A common 4G allele of a 4G/5G polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene is associated with increased transcription of the PAI-1 protein, which may lead to decreased fibrinolysis. It has th
Publikováno v:
Thrombosis and Haemostasis. 80:791-797
SummaryThe presence of antiphospholipid antibodies (aPL) is strongly correlated with venous and arterial thrombosis, fetal loss and thrombocytopenia. This relation is called the antiphospholipid syndrome (APS). It is well recognized that thrombosis r
Autor:
Yvonne T. van der Schouw, Jan Dirk Banga, Jo J. M. Marx, Bart de Valk, Mark Roest, Mariëlle J. Tempelman, Philip G. de Groot, Jan J. Sixma
Publikováno v:
Circulation. 100(12)
Background —The genetic background of hereditary hemochromatosis ( HH ) is homozygosity for a cysteine-to-tyrosine transition at position 282 in the HFE gene. Heterozygosity for HH is associated with moderately increased iron levels and could be a
Autor:
Yvonne T. van der Schouw, Diederick E. Grobbee, Mark Roest, Jan J. Sixma, Mariëlle J. Tempelman, Jan Dirk Banga, Philip G. de Groot
Publikováno v:
American journal of epidemiology. 149(7)
Factor V Arg506Gln is the most common genetic risk factor for venous thrombosis and is associated with myocardial infarction in young women, especially among smokers. The authors studied the relation of factor V Arg506Gln to cardiovascular mortality