Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mariëlle J. F. M. van Kooten"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Rewriting genomes allows for complete annotation of gene regulatory elements. Here the authors compare endogenous and rewritten segments of a genome and find extensive transcriptional changes, based on which they formulate design principles that aid
Externí odkaz:
https://doaj.org/article/ccf4854386d044bab964b2abe2e588e7
Publikováno v:
Nature Communications, 12
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Sequence rewriting enables low-cost genome synthesis and the design of biological systems with orthogonal genetic codes. The error-free, robust rewriting of nucleotide sequences can be achieved with a complete annotation of gene regulatory elements.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0188dfb69753e62d6c87c544684fdcf3
Autor:
Luca Del Medico, Carlos Eduardo Flores-Tinoco, Matthias Christen, Alexander Wölfle, Beat Christen, Samuel Deutsch, Rym Guennoun, Jonathan E. Venetz, Philipp Schächle, Flavia Tschan, Donat Appert, Mariëlle J. F. M. van Kooten, Yves Bucher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 116 (16)
Proceedings of the National Academy of Sciences of the United States of America, 116 (16)
Understanding how to program biological functions into artificial DNA sequences remains a key challenge in synthetic genomics. Here, we report the chemical synthesis and testing of Caulobacter ethensis-2.0 (C. eth-2.0), a rewritten bacterial genome c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6285e76a6c86ebf560d9c34f1c0fd5
https://pubmed.ncbi.nlm.nih.gov/30936302
https://pubmed.ncbi.nlm.nih.gov/30936302