Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mariël G. Pikkemaat"'
Autor:
Rikki Franklin Frederiksen, Jannice Schau Slettemeås, Silje Granstad, Karin Lagesen, Mariel G. Pikkemaat, Anne Margrete Urdahl, Roger Simm
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Antimicrobial resistance is a major threat to human health and must be approached from a One Health perspective. Use of antimicrobials in animal husbandry can lead to dissemination and persistence of resistance in human pathogens. Polyether ionophore
Externí odkaz:
https://doaj.org/article/1ac3fff732524187b3079ec9bdd8f927
Publikováno v:
Biochemistry, 42(26), 8047-8053. AMER CHEMICAL SOC
Haloalkane dehalogenase from Rhodococcus rhodochrous NCIMB 13064 (DhaA) catalyzes the hydrolysis of carbon-halogen bonds in a wide range of haloalkanes. We examined the steady-state and pre-steady-state kinetics of halopropane conversion by DhaA to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f77ea7ee1550380cd84c6b3cc3a1a9
https://doi.org/10.1021/bi026907m
https://doi.org/10.1021/bi026907m
Publikováno v:
Protein Engineering, 15(3), 185-192
Haloalkane dehalogenase (DhlA) was used as a model protein to explore the possibility to use molecular dynamics (MD) simulations as a tool to identify flexible regions in proteins that can serve as a target for stability enhancement by introduction o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b31e5dedaa7f3ec9997f60aab5e42c
https://doi.org/10.1093/protein/15.3.185
https://doi.org/10.1093/protein/15.3.185
Autor:
Dick B. Janssen, Henriëtte J. Rozeboom, Ivo S. Ridder, Mariël G. Pikkemaat, Kor H. Kalk, Bauke W. Dijkstra
Publikováno v:
Biochemistry, 38(37), 12052-12061. AMER CHEMICAL SOC
Haloalkane dehalogenase (DhlA) converts haloalkanes to their corresponding alcohols and halide ions. The rate-limiting step in the reaction of DhlA is the release of the halide ion. The kinetics of halide release have been analyzed by measuring halid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6834722cc7c040dc4fc9353f838ade5c
https://research.rug.nl/en/publications/4c78ed32-57fe-41f0-ba3b-1c4ae1299160
https://research.rug.nl/en/publications/4c78ed32-57fe-41f0-ba3b-1c4ae1299160
Autor:
Dick B. Janssen, Mariël G. Pikkemaat
Publikováno v:
Nucleic Acids Research, 30(8):35. Oxford University Press
Directed evolution techniques allow us to genuinely mimic molecular evolution in vitro. To enhance this imitation of natural evolutionary processes on a laboratory scale in even more detail, we developed an in vitro method for the generation of rando
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516f0016403aa7e1e3f1bc2422d26068
https://europepmc.org/articles/PMC113230/
https://europepmc.org/articles/PMC113230/
