Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells

Autor: Mariángeles Noto Llana, Sebastián H. Sarnacki, Andrea L. Morales, María del R. Aya Castañeda, Mónica N. Giacomodonato, Guillermo Blanco, María C. Cerquetti

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)

Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA. Although the pathogenesis remains unclear, it is known that IL-17 pl

Externí odkaz: https://doaj.org/article/59094606ad114f5e9dcc056044fc85e5

Consumption of Lactobacillus casei fermented milk prevents Salmonella reactive arthritis by modulating IL-23/IL-17 expression.

Autor: Mariángeles Noto Llana, Sebastián Hernán Sarnacki, María del Rosario Aya Castañeda, María Isabel Bernal, Mónica Nancy Giacomodonato, María Cristina Cerquetti

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82588 (2013)

Reactive arthritis is the development of sterile joint inflammation as a sequel to a remote infection, often in the gut. We have previously shown that a low dose of S. enteritidis inoculated to streptomycin-pretreated mice generates a self-limiting e

Externí odkaz: https://doaj.org/article/94cf553b8d864f98ac9f5869fdf60a18

Neutralization of Staphylococcus aureus Protein A Prevents Exacerbated Osteoclast Activity and Bone Loss during Osteomyelitis

Autor: Ana-Katharina E. Gehrke, Andrea Mendoza-Bertelli, Camila Ledo, Cintia D. Gonzalez, Mariángeles Noto Llana, Cintia Blanco, Daniel O. Sordelli, Nicole E. Putman, James E. Cassat, María Victoria Delpino, Marisa I. Gómez

Publikováno v: Antimicrob Agents Chemother

Osteomyelitis caused by Staphylococcus aureus is an important and current health care problem worldwide. Treatment of this infection frequently fails not only due to the increasing incidence of antimicrobial-resistant isolates but also because of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbcd824bf24e347537be68b399f56fa
https://doi.org/10.1128/aac.01140-22

Acapsular Staphylococcus aureus with a non-functional agr regains capsule expression after passage through the bloodstream in a bacteremia mouse model

Autor: Rocío E Díaz, Fernanda Roxana Buzzola, Carlos M Suligoy, Lorena Tuchscherr, Bettina Löffler, Ana-Katharina Gehrke, Sindy Wendler, Natalie Ring, J. Ross Fitzgerald, Marisa Ines Gomez, Daniel O. Sordelli, Mariángeles Noto Llana, Joana Alves, Gonzalo Yebra

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Suligoy, C M, Díaz, R E, Gehrke, A-K, Ring, N, Yebra, G, Alves, J, Gómez, M I, Wendler, S, Fitzgerald, J R, Tuchscherr, L, Löffler, B, Sordelli, D O, Llana, M N & Buzzola, F R 2020, ' Acapsular Staphylococcus aureus with a non-functional agr regains capsule expression after passage through the bloodstream in a bacteremia mouse model ', Scientific Reports, vol. 10, no. 1, pp. 14108 . https://doi.org/10.1038/s41598-020-70671-1
Scientific Reports

Selection pressures exerted on Staphylococcus aureus by host factors during infection may lead to the emergence of regulatory phenotypes better adapted to the infection site. Traits convenient for persistence may be fixed by mutation thus turning the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5856014dcca9c05c9783e03651ec7a
http://link.springer.com/article/10.1038/s41598-020-70671-1

Mutation of Agr Is Associated with the Adaptation of Staphylococcus aureus to the Host during Chronic Osteomyelitis

Autor: Lucía Álvarez, Santiago M. Lattar, Cintia Daniela Gonzalez, Carlos M Suligoy, Fernanda R. Buzzola, Mariángeles Noto Llana, Marisa Ines Gomez, Daniel O. Sordelli, D. Ashley Robinson

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)

Selection pressures exerted on Staphylococcus aureus by host factors may lead to the emergence of mutants better adapted to the evolving conditions at the infection site. This study was aimed at identifying the changes that occur in S. aureus exposed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d591762f9d07acd126a6fc7632ec1f42