Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marián Alonso-Mariño"'
Autor:
María A. Urbaneja, Lars Skjærven, Oscar Aubi, Jarl Underhaug, David J. López, Igor Arregi, Marián Alonso-Mariño, Andoni Cuevas, José A. Rodríguez, Aurora Martinez, Sonia Bañuelos
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Nucleophosmin (NPM) is a nucleolar protein involved in ribosome assembly and cell homeostasis. Mutations in the C-terminal domain of NPM that impair native folding and localization are associated with acute myeloid leukemia (AML). We have pe
Externí odkaz:
https://doaj.org/article/84e9066a4962437e9c1ac1b64a684a28
Autor:
Igor Arregi, Jorge Falces, Anne Olazabal-Herrero, Marián Alonso-Mariño, Stefka G Taneva, José A Rodríguez, María A Urbaneja, Sonia Bañuelos
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130610 (2015)
Nucleophosmin (NPM) is a nucleocytoplasmic shuttling protein, normally enriched in nucleoli, that performs several activities related to cell growth. NPM mutations are characteristic of a subtype of acute myeloid leukemia (AML), where mutant NPM seem
Externí odkaz:
https://doaj.org/article/62f961a987574240896c9861380d3dfd
Autor:
Mikel García-Alija, Mikel Hurtado, Sonia Bañuelos, David J. López, Marián Alonso-Mariño, Igor de la Arada, María A. Urbaneja, Jon Mentxaka, Ander de Blas
Publikováno v:
DNA Repair. 88:102809
Nucleophosmin (NPM1), an abundant, nucleolar protein with multiple functions affecting cell homeostasis, has also been recently involved in DNA damage repair. The roles of NPM1 in different repair pathways remain however to be elucidated. NPM1 has be
Autor:
Oscar Aubi, Jarl Underhaug, Marián Alonso-Mariño, David J. López, Sonia Bañuelos, María A. Urbaneja, Igor Arregi, Andoni Cuevas, Jose Antonio Rodriguez, Aurora Martinez, Lars Skjærven
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Nucleophosmin (NPM) is a nucleolar protein involved in ribosome assembly and cell homeostasis. Mutations in the C-terminal domain of NPM that impair native folding and localization are associated with acute myeloid leukemia (AML). We have performed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2758035205991528fde48e3fa87d43fb
https://hdl.handle.net/1956/17367
https://hdl.handle.net/1956/17367
Autor:
Marián Alonso-Mariño, Ane Metola, Ana Rosa Viguera, Félix M. Goñi, Lena Mäler, Ana M. Bouchet, Tammo Diercks
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1859(11)
The immunity proteins against pore-forming colicins represent a family of integral membrane proteins that reside in the inner membrane of producing cells. Cai, the colicin A immunity protein, was characterized here in detergent micelles by circular d
Autor:
Marián Alonso-Mariño, Jose Antonio Rodriguez, Juan J. Garcia-Vallejo, Igor Arregi, Iraia García-Santisteban, María A. Urbaneja, Sonia Bañuelos
Publikováno v:
Cellular and Molecular Life Sciences, 73(24), 4685-4699. Birkhauser Verlag Basel
Garcia-Santisteban, I, Arregi, I, Alonso-Marino, M, Urbaneja, M A, Garcia-Vallejo, J J, Banuelos, S & Rodriguez, J A 2016, ' A cellular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K ', Cellular and Molecular Life Sciences, vol. 73, no. 24, pp. 4685-4699 . https://doi.org/10.1007/s00018-016-2292-0
Garcia-Santisteban, I, Arregi, I, Alonso-Marino, M, Urbaneja, M A, Garcia-Vallejo, J J, Banuelos, S & Rodriguez, J A 2016, ' A cellular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K ', Cellular and Molecular Life Sciences, vol. 73, no. 24, pp. 4685-4699 . https://doi.org/10.1007/s00018-016-2292-0
The exportin CRM1 binds nuclear export signals (NESs), and mediates active transport of NES-bearing proteins from the nucleus to the cytoplasm. Structural and biochemical analyses have uncovered the molecular mechanisms underlying CRM1/NES interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3db9d6058534d6fcd5bc3492a0ff98
https://research.vumc.nl/en/publications/4b1e27dc-df92-4d91-91d8-93c10711935d
https://research.vumc.nl/en/publications/4b1e27dc-df92-4d91-91d8-93c10711935d
Autor:
Marián Alonso-Mariño, Cristina Arnulphi, Ivan L. Bermejo, Alain Ibáñez de Opakua, Félix M. Goñi, Ana Rosa Viguera
Publikováno v:
Biophysical journal. 105(6)
The colicins are bacteriocins that target Escherichia coli and kill bacterial cells through different mechanisms. Colicin A forms ion channels in the inner membranes of nonimmune bacteria. This activity resides exclusively in its C-terminal fragment
Autor:
Stefka G. Taneva, Georgina Ormaza, Sonia Bañuelos, Xabier Calle, Marián Alonso-Mariño, María A. Urbaneja, Benoit Lectez
Publikováno v:
FEBS letters. 587(14)
Nucleophosmin (NPM) is a nucleolar protein involved in ribosome biogenesis. NPM1 gene is frequently mutated in acute myeloid leukaemia (AML), correlating with aberrant cytoplasmic localization of the protein. NPM attachment to the nucleolus in physio