Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Mari, Kono"'
Autor:
Yuki Miyajima, Hideki Niimi, Tomohiro Ueno, Atsushi Matsui, Yoshitsugu Higashi, Nozomi Kojima, Mari Kono, Yosuke Iwasaki, Kentaro Nagaoka, Yoshihiro Yamamoto, Isao Kitajima
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundCell population data (CPD) parameters related to neutrophils, such as fluorescent light intensity (NE-SFL) and fluorescent light distribution width index (NE-WY), have emerged as potential biomarkers for sepsis. However, the diagnostic impl
Externí odkaz:
https://doaj.org/article/3322511b88db4d6dbdb257f944772b93
Autor:
Kah Wai Looi, Yukari Matsui, Mari Kono, Chandramathi Samudi, Nozomi Kojima, Jin Xu Ong, Chin Aun Tan, Chong Siang Ang, Peter Hao Yuan Tan, Hemalatha Shamnugam, Shamala Devi Sekaran, Sharifah Faridah Syed Omar, Lucy Chai See Lum
Publikováno v:
International Journal of Infectious Diseases, Vol 110, Iss , Pp 187-194 (2021)
ABSTRACT: Objectives: Progression of dengue is often associated with thrombocytopenia resulting from viral-induced bone marrow suppression and immune-mediated peripheral platelet consumption. Immature platelet fraction (IPF), which can be measured us
Externí odkaz:
https://doaj.org/article/e58d08519cac440a998afcab8e94e66b
Autor:
Mari Kono, Lila E. Hoachlander-Hobby, Saurav Majumder, Ronit Schwartz, Colleen Byrnes, Hongling Zhu, Richard L. Proia
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 6, Pp 100225- (2022)
Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite that serves as a potent extracellular signaling molecule. Metabolic regulation of extracellular S1P levels impacts key cellular activities through altered S1P receptor signaling. Although the
Externí odkaz:
https://doaj.org/article/804486a37c684efa902d7bf13e3f8314
Autor:
Kazu Hatanaka, Yasushi Shirahase, Toshiyuki Yoshida, Mari Kono, Naoki Toya, Shin-Ichi Sakasegawa, Kenji Konishi, Tadashi Yamamoto, Kuniyasu Ochiai, Shogo Takashiba
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0268671 (2022)
Periodontal disease is a chronic inflammatory condition caused by periodontal pathogens in the gingival sulcus. Short-chain fatty acids (SCFAs) produced by causal bacteria are closely related to the onset and progression of periodontal disease and ha
Externí odkaz:
https://doaj.org/article/b8053b94526a451e8ad19ad0ed6a9eda
Autor:
Naoki Yamamoto, Takuya Tokumon, Ayako Obuchi, Mari Kono, Katsuyasu Saigo, Mamoru Tanida, Yuri Ikeda‐Matsuo, Kazuya Sobue
Publikováno v:
Journal of Neurochemistry. 163:517-530
Inflammation associated with viral infection of the nervous system has been involved in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease (AD) and multiple sclerosis. Polyinosinic:polycytidylic acid (poly[I:C]) is a Toll-lik
Autor:
Mari Kono, Shiori Matsuhiroya, Ayako Obuchi, Takayuki Takahashi, Shion Imoto, Seiji Kawano, Katsuyasu Saigo
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
Objective Reactive oxygen species (ROS) production by neutrophils induces pulmonary endothelial cell damage and results in acute lung injury (ALI). We previously reported that deferasirox (DFS), an iron-chelating agent, inhibits the ROS production an
Externí odkaz:
https://doaj.org/article/798e927a1ab74d6cbb1beb77408d01f7
Autor:
Eric Engelbrecht, Michel V Levesque, Liqun He, Michael Vanlandewijck, Anja Nitzsche, Hira Niazi, Andrew Kuo, Sasha A Singh, Masanori Aikawa, Kristina Holton, Richard L Proia, Mari Kono, William T Pu, Eric Camerer, Christer Betsholtz, Timothy Hla
Publikováno v:
eLife, Vol 9 (2020)
Despite the medical importance of G protein-coupled receptors (GPCRs), in vivo cellular heterogeneity of GPCR signaling and downstream transcriptional responses are not understood. We report the comprehensive characterization of transcriptomes (bulk
Externí odkaz:
https://doaj.org/article/2b95d8d5a479422885261efe96819fc7
Autor:
Benjamin A Clarke, Saurav Majumder, Hongling Zhu, Y Terry Lee, Mari Kono, Cuiling Li, Caroline Khanna, Hailey Blain, Ronit Schwartz, Vienna L Huso, Colleen Byrnes, Galina Tuymetova, Teresa M Dunn, Maria L Allende, Richard L Proia
Publikováno v:
eLife, Vol 8 (2019)
Sphingolipids are membrane and bioactive lipids that are required for many aspects of normal mammalian development and physiology. However, the importance of the regulatory mechanisms that control sphingolipid levels in these processes is not well un
Externí odkaz:
https://doaj.org/article/2c0b70daaf154f68988f8dd68ab972c9
Autor:
Mari Kono, Elizabeth G. Conlon, Samantha Y. Lux, Keisuke Yanagida, Timothy Hla, Richard L. Proia
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
G protein-coupled receptors are involved in numerous physiological functions, thus, they represent potential pharmaceutical targets. Here Kono et al. describe a new mouse model to image GPCR activation in real-time by exploiting firefly split lucifer
Externí odkaz:
https://doaj.org/article/c32511cc563843f48d30e2af1c4c9730
Autor:
Hongling Zhu, Colleen Byrnes, Y. Terry Lee, Galina Tuymetova, Hannah B. D. Duffy, Jenna Y. Bakir, Sydney N. Pettit, Jabili Angina, Danielle A. Springer, Maria L. Allende, Mari Kono, Richard L. Proia
Publikováno v:
The FASEB Journal. 37