Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Marharyta Petukh"'
Autor:
Shelby M. Baker, Marharyta Petukh
Publikováno v:
ACS Omega, Vol 5, Iss 45, Pp 29222-29230 (2020)
Externí odkaz:
https://doaj.org/article/f23c4bede7e940edb836baf8e46f179f
Autor:
José Antonio Gavira, Vadim M. Gumerov, Miriam Rico-Jiménez, Marharyta Petukh, Amit A. Upadhyay, Alvaro Ortega, Miguel A. Matilla, Igor B. Zhulin, Tino Krell
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Chemoreceptor-based signaling pathways are among the major modes of bacterial signal transduction, and Pseudomonas aeruginosa PAO1 is an important model to study their function. Of the 26 chemoreceptors of this strain, PctA has a broad ligan
Externí odkaz:
https://doaj.org/article/137df719cfa54b34b83335f426bb5523
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 7, p e1004276 (2015)
A new methodology termed Single Amino Acid Mutation based change in Binding free Energy (SAAMBE) was developed to predict the changes of the binding free energy caused by mutations. The method utilizes 3D structures of the corresponding protein-prote
Externí odkaz:
https://doaj.org/article/7b62c72008e94e7ca16bc68735d92c43
Autor:
Marharyta Petukh, Bohua Wu, Shannon Stefl, Nick Smith, David Hyde-Volpe, Li Wang, Emil Alexov
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111604 (2014)
Chronic Beryllium (Be) Disease (CBD) is a granulomatous disorder that predominantly affects the lung. The CBD is caused by Be exposure of individuals carrying the HLA-DP2 protein of the major histocompatibility complex class II (MHCII). While the inv
Externí odkaz:
https://doaj.org/article/ed4bbea9e4a3442c8eeb6b5b7aa702cf
Autor:
Emil Alexov, Swagata Pahari, Yunhui Peng, Chuan Li, Zhe Jia, Sankar Basu, Arghya Chakravorty, Lin Li, Shailesh Kumar Panday, Mahesh Koirala, Marharyta Petukh
Publikováno v:
Journal of Computational Chemistry
Electrostatic potential, energies, and forces affect virtually any process in molecular biology, however, computing these quantities is a difficult task due to irregularly shaped macromolecules and the presence of water. Here, we report a new edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb6f4b7439a1b3d5dbbfef179ad7de2
http://europepmc.org/articles/PMC6771749
http://europepmc.org/articles/PMC6771749
Autor:
Vadim M. Gumerov, Tino Krell, Amit A. Upadhyay, Álvaro Ortega, Jose A. Gavira, Miriam Rico-Jiménez, Marharyta Petukh, Igor B. Zhulin, Miguel A. Matilla
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
mBio
mBio, Vol 11, Iss 1, p e03066-19 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
mBio
mBio, Vol 11, Iss 1, p e03066-19 (2020)
Chemoreceptor-based signaling pathways are among the major modes of bacterial signal transduction, and Pseudomonas aeruginosa PAO1 is an important model to study their function. Of the 26 chemoreceptors of this strain, PctA has a broad ligand range a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85ab7db6cba01c3792ad92f03cd844a
https://journals.asm.org/doi/10.1128/mBio.03066-19
https://journals.asm.org/doi/10.1128/mBio.03066-19
Chemoreceptors are principal components of the bacterial sensory system that modulates cellular motility. They detect changes in the environment and transmit information to CheA histidine kinase, which ultimately controls cellular flagellar motors. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc236954d6516abc8865eea4bd98587f
Publikováno v:
Journal of Computational Chemistry. 36:2381-2393
Ions are engaged in multiple biological processes in cells. By binding to the macromolecules or being mobile in the solvent, they maintain the integrity of the structure of macromolecules; participate in their enzymatic activity; or screen electrosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3403b021e3a73c624b8c0fb4802dfd0
https://doi.org/10.1002/jcc.24218
https://doi.org/10.1002/jcc.24218
Publikováno v:
Current Opinion in Structural Biology. 32:18-24
This review emphasizes the effects of naturally occurring mutations on structural features and physico-chemical properties of proteins. The basic protein characteristics considered are stability, dynamics, and the binding of proteins and methods for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e72e323963a97281f366af6207c4e36
https://doi.org/10.1016/j.sbi.2015.01.003
https://doi.org/10.1016/j.sbi.2015.01.003
Publikováno v:
Journal of Chemical Theory and Computation
The crucial prerequisite for proper biological function is the protein’s ability to establish highly selective interactions with macromolecular partners. A missense mutation that alters the protein binding affinity may cause significant perturbatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae31ad8139c127e37353972148c7764
http://europepmc.org/articles/PMC3985714
http://europepmc.org/articles/PMC3985714