Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marguerite-Marie Le Pannérer"'
Autor:
Jeannine Diesch, Marguerite-Marie Le Pannérer, René Winkler, Raquel Casquero, Matthias Muhar, Mark van der Garde, Michael Maher, Carolina Martínez Herráez, Joan J. Bech-Serra, Michaela Fellner, Philipp Rathert, Nigel Brooks, Lurdes Zamora, Antonio Gentilella, Carolina de la Torre, Johannes Zuber, Katharina S. Götze, Marcus Buschbeck
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Azacitidine (AZA) treatment is used for patients with myelodysplasias that cannot undergo bone marrow transplantation; however, AZA treatment is only partially effective. Here the authors show synergy of AZA with compounds inhibiting the chromatin re
Externí odkaz:
https://doaj.org/article/d0619bde27374a0bbc9ce933934d9f91
Autor:
Michael Maher, Jeannine Diesch, Marguerite-Marie Le Pannérer, Marta Cabezón, Mar Mallo, Sara Vergara, Aleix Méndez López, Alba Mesa Tudel, Francesc Solé, Marc Sorigue, Lurdes Zamora, Isabel Granada, Marcus Buschbeck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Haematopoietic malignancies are frequently characterized by karyotypic abnormalities. The development of targeted drugs has been pioneered with compounds against gene products of fusion genes caused by chromosomal translocations. While polys
Externí odkaz:
https://doaj.org/article/9d9b4bb0f2df4fc2af58a8e00e00bdae
Autor:
Marguerite-Marie Le Pannérer, Jeannine Diesch, Raquel Casquero, Michael Maher, Olga Garcia, Torsten Haferlach, Johannes Zuber, Andrea Kündgen, Katharina S. Götze, Marcus Buschbeck
Publikováno v:
HemaSphere, Vol 6, Iss 11, p e792 (2022)
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic disorders characterized by dysplasia, ineffective hematopoiesis, and predisposition to secondary acute myeloid leukemias (sAML). Azacitidine (AZA) is the standard care for hig
Externí odkaz:
https://doaj.org/article/f33002380b0a4de08506dd7747196f61
Autor:
Marguerite-Marie Le Pannérer, Marcus Buschbeck, René Winkler, Gaël Roué, Miranda Fernández-Serrano, Juliana Carvalho Santos
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 253, p 253 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
In a wide range of lymphoid neoplasms, the process of malignant transformation is associated with somatic mutations in B cells that affect the epigenetic machinery. Consequential alterations in histone modifications contribute to disease-specific cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b3f9f1a07c779f75d8ad7b789bc758
https://www.mdpi.com/1422-0067/23/1/253
https://www.mdpi.com/1422-0067/23/1/253
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1746, p 1746 (2021)
Cancers, Vol 13, Iss 1746, p 1746 (2021)
Simple Summary The genome is stored in the limited space of the nucleus in a highly condensed form. The regulation of this packaging contributes to determining the accessibility of genes and is important for cell function. Genes affecting the genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7e0aa4a4bda5722e3e76798a779430
https://ddd.uab.cat/record/270647
https://ddd.uab.cat/record/270647
Autor:
Antonio Gentilella, Johannes Zuber, Marguerite-Marie Le Pannérer, Carolina De La Torre, Michael Maher, René Winkler, Carolina Martínez Herráez, Lurdes Zamora, Joan Josep Bech-Serra, Matthias Muhar, Nigel Brooks, Marcus Buschbeck, Katharina Götze, Michaela Fellner, Mark van der Garde, Philipp Rathert, Raquel Casquero, Jeannine Diesch
Publikováno v:
Nature Communications
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The nucleotide analogue azacitidine (AZA) is currently the best treatment option for patients with high-risk myelodysplastic syndromes (MDS). However, only half of treated patients respond and of these almost all eventually relapse. New treatment opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0435f0addf061fc6e532fd6d31125fa2
https://ddd.uab.cat/record/270585
https://ddd.uab.cat/record/270585
Autor:
Lumir Krejci, Manlio Vinciguerra, Marguerite Marie Le Pannérer, Oriana Lo Re, Valerio Pazienza, Šárka Pospíšilová, Carlo Riccardi, Fedor Nikulenkov, Oxana Bereshchenko, A. Francis Stewart, Giovanni Li Volti, Cesarina Giallongo, Marcus Buschbeck, Tommaso Mazza, Libor Červinek, Jana Kotašková, Giuseppe A. Palumbo, Sara Flamini
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Clinical Epigenetics
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Recercat. Dipósit de la Recerca de Catalunya
Universitat Autònoma de Barcelona
Clinical Epigenetics
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Recercat. Dipósit de la Recerca de Catalunya
Background Epigenetic regulation is important in hematopoiesis, but the involvement of histone variants is poorly understood. Myelodysplastic syndromes (MDS) are heterogeneous clonal hematopoietic stem cell (HSC) disorders characterized by ineffectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04053792e76e338e702e059bbe66bddb
https://ddd.uab.cat/record/223380
https://ddd.uab.cat/record/223380