Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Marguerite M. Vantangoli"'
Autor:
Pranita K. Kabadi, Marguerite M. Vantangoli, April L. Rodd, Elizabeth Leary, Samantha J. Madnick, Jeffrey R. Morgan, Agnes Kane, Kim Boekelheide
Publikováno v:
BioTechniques, Vol 59, Iss 5, Pp 279-286 (2015)
Three-dimensional (3-D) in vitro platforms have been shown to closely recapitulate human physiology when compared with conventional two-dimensional (2-D) in vitro or in vivo animal model systems. This confers a substantial advantage in evaluating dis
Externí odkaz:
https://doaj.org/article/7ce370630ed5493cbf62d5256b42e802
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157997 (2016)
The development of three-dimensional (3D) cultures is increasing, as they are able to provide the utility of in vitro models and the strength of testing in physiologically relevant systems. When cultured in a scaffold-free agarose hydrogel system, MC
Externí odkaz:
https://doaj.org/article/5818c81a9d834455b4fe16f79c245769
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135426 (2015)
Three-dimensional (3D) cultures are increasing in use because of their ability to represent in vivo human physiology when compared to monolayer two-dimensional (2D) cultures. When grown in 3D using scaffold-free agarose hydrogels, MCF-7 human breast
Externí odkaz:
https://doaj.org/article/fbc11162452d4162a3d3d816d5643258
Autor:
Sara E Pacheco, Linnea M Anderson, Moses A Sandrof, Marguerite M Vantangoli, Susan J Hall, Kim Boekelheide
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44280 (2012)
Current human reproductive risk assessment methods rely on semen and serum hormone analyses, which are not easily comparable to the histopathological endpoints and mating studies used in animal testing. Because of these limitations, there is a need t
Externí odkaz:
https://doaj.org/article/1c1e3620b53c4e0ebd89d5cda46f59a6
Autor:
Toni-Marie Achilli, Kim Boekelheide, Marguerite M. Vantangoli, Sean P. Curran, Benjamin T. Wilks, Jeffrey R. Morgan, Elizabeth Leary
Publikováno v:
TECHNOLOGY. :54-63
None of the ABCG2 inhibitors are effective clinically against multidrug resistant tumors overexpressing ABCG2. New in vitro models are needed to characterize inhibitors and discover new ones. We report a 3D spheroid model and image-based method to qu
Autor:
Andre Kleensang, Marguerite M. Vantangoli, Shelly Odwin-DaCosta, Melvin E. Andersen, Kim Boekelheide, Mounir Bouhifd, Albert J. Fornace, Heng-Hong Li, Carolina B. Livi, Samantha Madnick, Alexandra Maertens, Michael Rosenberg, James D. Yager, Liang Zhao, Thomas Hartung
Publikováno v:
Scientific Reports. 6
Scientific Reports 6: Article number: 28994; published online: 26 July 2016; updated: 14 September 2016
Autor:
Shelly Odwin-DaCosta, Melvin E. Andersen, Heng-Hong Li, Mounir Bouhifd, James D. Yager, Liang Zhao, Andre Kleensang, Albert J. Fornace, Samantha J. Madnick, Carolina B. Livi, Michael Rosenberg, Alexandra Maertens, Kim Boekelheide, Thomas Hartung, Marguerite M. Vantangoli
Publikováno v:
Scientific Reports
Common recommendations for cell line authentication, annotation and quality control fall short addressing genetic heterogeneity. Within the Human Toxome Project, we demonstrate that there can be marked cellular and phenotypic heterogeneity in a singl
Autor:
Melvin E. Andersen, Kim Boekelheide, Salil N. Pendse, Alexandra Maertens, Rick A. Fasani, Dipanwita Roy, Marguerite M. Vantangoli, Michael Rosenberg, Thomas Hartung, James D. Yager, Albert J. Fornace, Samantha J. Madnick, Patrick D. McMullen
The twenty-first century vision for toxicology involves a transition away from high-dose animal studies and into in vitro and computational models. This movement requires mapping pathways of toxicity through an understanding of how in vitro systems r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743dd620c8fd883763cad4e170afb39b
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157997 (2016)
PLoS ONE
PLoS ONE
The development of three-dimensional (3D) cultures is increasing, as they are able to provide the utility of in vitro models and the strength of testing in physiologically relevant systems. When cultured in a scaffold-free agarose hydrogel system, MC
Autor:
Agnes B. Kane, Pranita K. Kabadi, Jeffrey R. Morgan, Marguerite M. Vantangoli, Elizabeth Leary, Kim Boekelheide, April L. Rodd, Samantha J. Madnick
Three-dimensional (3-D) in vitro platforms have been shown to closely recapitulate human physiology when compared with conventional two-dimensional (2-D) in vitro or in vivo animal model systems. This confers a substantial advantage in evaluating dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b69ab9ab183820f0943a18824800c72
https://europepmc.org/articles/PMC4804457/
https://europepmc.org/articles/PMC4804457/