Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Marguerite Ennis"'
Autor:
Lauren Podmore, Yekaterina Poloz, Catherine Iorio, Samar Mouaaz, Kevin Nixon, Petr Smirnov, Brianna McDonnell, Sonya Lam, Bowen Zhang, Pirashaanthy Tharmapalan, Soumili Sarkar, Foram Vyas, Marguerite Ennis, Ryan Dowling, Vuk Stambolic
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113251- (2023)
Summary: Breast cancer (BC) prognosis and outcome are adversely affected by obesity. Hyperinsulinemia, common in the obese state, is associated with higher risk of death and recurrence in BC. Up to 80% of BCs overexpress the insulin receptor (INSR),
Externí odkaz:
https://doaj.org/article/0a98286f0bdb4289aa404e39db449838
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Crown-like structures of the breast (CLS-B), defined by the clustering of macrophages (identified using CD68 immunohistochemical staining) to surround a dying adipocyte, are a sign of adipose-tissue inflammation. In human cohorts, CLS-B posi
Externí odkaz:
https://doaj.org/article/7c78499a9b124266883a99ee2d8c39fe
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveTo examine the association between Karnofsky Performance Status (“KPS”) and brain-specific progression-free survival (“bsPFS”) among patients with breast cancer brain metastases (“BCBrM”).MethodsUsing a previously compiled retros
Externí odkaz:
https://doaj.org/article/2bb32220ba65466485ac39e65a15475b
Autor:
Pamela J. Goodwin, Ryan J. O. Dowling, Marguerite Ennis, Bingshu E. Chen, Wendy R. Parulekar, Lois E. Shepherd, Margot J. Burnell, Rachel Vander Meer, Andrea Molckovsky, Anagha Gurjal, Karen A. Gelmon, Jennifer A. Ligibel, Dawn L. Hershman, Ingrid A. Mayer, Timothy J. Whelan, Timothy J. Hobday, Priya Rastogi, Manuela Rabaglio-Poretti, Julie Lemieux, Alastair M. Thompson, Daniel W. Rea, Vuk Stambolic
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Metformin may exert anticancer effects through indirect (mediated by metabolic changes) or direct mechanisms. The goal was to examine metformin impact on metabolic factors in non-diabetic subjects and determine whether this impact varies by
Externí odkaz:
https://doaj.org/article/ed8c22cdd63b4d8ab3a69bbf18ba9909
Autor:
Diana P Arteaga, Corina DeKraker, Marguerite Ennis, Nicole Dewey, Emily A Goebel, Stephen Welch, Isabel Pimentel, Joseph E Ippolito, Ana Elisa Lohmann
Publikováno v:
JNCI Monographs. 2023:49-55
Background Obesity is a known risk factor for developing endometrial cancer. However, the association of obesity with endometrial cancer (EC) outcomes has not been clearly established. This study examined how outcomes in women with early stage EC var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6870bc73235700e508a5214784c0ce22
https://doi.org/10.1093/jncimonographs/lgad012
https://doi.org/10.1093/jncimonographs/lgad012
Autor:
Pamela J. Goodwin, Bingshu E Chen, Karen A Gelmon, Timothy J Whelan, Marguerite Ennis, Julie Lemieux, Jennifer A Ligibel, Dawn L Hershman, Ingrid A Mayer, Timothy J Hobday, Judith M Bliss, Priya Rastogi, Manuela Rabaglio-Poretti, Som D. Mukherjee, Robert R Mackey, Vandana G Abramson, Conrad Oja, Robert Wesolowski, Alastair M Thompson, Daniel W Rea, Paul M Stos, Lois E Shepherd, Vuk Stambolic, Wendy R Parulekar
Publikováno v:
Cancer Research. 82:GS1-08
Background: MET has been associated with beneficial anti-cancer effects in epidemiologic and preclinical research. It may act indirectly by reversing obesity associated physiologic changes or directly via mitochondrial mediated effects on LKB1/AMPK/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b3155b6c0daa50d7fd73f3daf3dfe41
https://doi.org/10.1158/1538-7445.sabcs21-gs1-08
https://doi.org/10.1158/1538-7445.sabcs21-gs1-08
Autor:
Rania Chehade, Maleeha A Qazi, Marguerite Ennis, Arjun Sahgal, Sunit Das, Sharon Nofech-Mozes, Katarzyna J Jerzak
Publikováno v:
Neuro-oncology advances. 4(1)
Background To evaluate the potential intracranial efficacy of immunotherapy among patients with breast cancer brain metastases (BrM), we analyzed the immunohistochemical expression of programmed death-ligand 1 (PD-L1), a predictive biomarker of respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ea455073f83e552d05dd51efc478ca
https://pubmed.ncbi.nlm.nih.gov/36299795
https://pubmed.ncbi.nlm.nih.gov/36299795
Autor:
Daniel Rea, Marguerite Ennis, Vuk Stambolic, Timothy J. Hobday, Ingrid A. Mayer, Manuela Rabaglio-Poretti, Julie Lemieux, Anagha Gurjal, Bingshu E. Chen, Rachel Vander Meer, Andrea Molckovsky, Dawn L. Hershman, Karen A. Gelmon, Timothy J. Whelan, Margot J. Burnell, Priya Rastogi, Jennifer A. Ligibel, Ryan J. O. Dowling, Alastair M. Thompson, Pamela J. Goodwin, Wendy R. Parulekar, Lois E. Shepherd
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
NPJ Breast Cancer
NPJ Breast Cancer
Metformin may exert anticancer effects through indirect (mediated by metabolic changes) or direct mechanisms. The goal was to examine metformin impact on metabolic factors in non-diabetic subjects and determine whether this impact varies by baseline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c408be1b9be9c798f3624df957abe98c
https://doaj.org/article/ed8c22cdd63b4d8ab3a69bbf18ba9909
https://doaj.org/article/ed8c22cdd63b4d8ab3a69bbf18ba9909
Autor:
Sara V Soldera, Marguerite Ennis, Domen Ribnikar, Isabel Pimentel, Eitan Amir, Pamela J. Goodwin, Ana Elisa Lohmann
Publikováno v:
JNCI Journal of the National Cancer Institute
Background Obesity at breast cancer (BC) diagnosis has been associated with poor outcome, although the magnitude of effect in different BC subtypes is uncertain. We report on the association of obesity or overweight at diagnosis of nonmetastatic BC w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4dfe470ffc63628584657c917857f9
https://doi.org/10.1093/jnci/djab023
https://doi.org/10.1093/jnci/djab023
Autor:
Vuk Stambolic, Karina Bukhanov, Ryan J.O. Dowling, Marguerite Ennis, Jaime Escallon, Pamela J. Goodwin, Martin C. Chang
Publikováno v:
Cancer Research. 81:PS18-25
Background and Rationale: Biomarker evaluation on breast tumor tissue is an important component of clinical research. There is a concern that tissues collected at different times (pre- vs intra-op) and with different techniques (core biopsy vs. surgi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e55b8fa0ed976c6085560073986fac3
https://doi.org/10.1158/1538-7445.sabcs20-ps18-25
https://doi.org/10.1158/1538-7445.sabcs20-ps18-25