Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Margrit Urbanek"'
Autor:
Matthew Dapas, Frederick T J Lin, Girish N Nadkarni, Ryan Sisk, Richard S Legro, Margrit Urbanek, M Geoffrey Hayes, Andrea Dunaif
Publikováno v:
PLoS Medicine, Vol 17, Iss 6, p e1003132 (2020)
BackgroundPolycystic ovary syndrome (PCOS) is a common, complex genetic disorder affecting up to 15% of reproductive-age women worldwide, depending on the diagnostic criteria applied. These diagnostic criteria are based on expert opinion and have bee
Externí odkaz:
https://doaj.org/article/b3d72e70484242e4bd8efa9a4d77f39b
Autor:
Felix Day, Tugce Karaderi, Michelle R Jones, Cindy Meun, Chunyan He, Alex Drong, Peter Kraft, Nan Lin, Hongyan Huang, Linda Broer, Reedik Magi, Richa Saxena, Triin Laisk, Margrit Urbanek, M Geoffrey Hayes, Gudmar Thorleifsson, Juan Fernandez-Tajes, Anubha Mahajan, Benjamin H Mullin, Bronwyn G A Stuckey, Timothy D Spector, Scott G Wilson, Mark O Goodarzi, Lea Davis, Barbara Obermayer-Pietsch, André G Uitterlinden, Verneri Anttila, Benjamin M Neale, Marjo-Riitta Jarvelin, Bart Fauser, Irina Kowalska, Jenny A Visser, Marianne Andersen, Ken Ong, Elisabet Stener-Victorin, David Ehrmann, Richard S Legro, Andres Salumets, Mark I McCarthy, Laure Morin-Papunen, Unnur Thorsteinsdottir, Kari Stefansson, andMe Research Team, Unnur Styrkarsdottir, John R B Perry, Andrea Dunaif, Joop Laven, Steve Franks, Cecilia M Lindgren, Corrine K Welt
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008517 (2019)
[This corrects the article DOI: 10.1371/journal.pgen.1007813.].
Externí odkaz:
https://doaj.org/article/758400ebfc3d4b0da53963dd663aaad5
Autor:
Felix Day, Tugce Karaderi, Michelle R Jones, Cindy Meun, Chunyan He, Alex Drong, Peter Kraft, Nan Lin, Hongyan Huang, Linda Broer, Reedik Magi, Richa Saxena, Triin Laisk, Margrit Urbanek, M Geoffrey Hayes, Gudmar Thorleifsson, Juan Fernandez-Tajes, Anubha Mahajan, Benjamin H Mullin, Bronwyn G A Stuckey, Timothy D Spector, Scott G Wilson, Mark O Goodarzi, Lea Davis, Barbara Obermayer-Pietsch, André G Uitterlinden, Verneri Anttila, Benjamin M Neale, Marjo-Riitta Jarvelin, Bart Fauser, Irina Kowalska, Jenny A Visser, Marianne Andersen, Ken Ong, Elisabet Stener-Victorin, David Ehrmann, Richard S Legro, Andres Salumets, Mark I McCarthy, Laure Morin-Papunen, Unnur Thorsteinsdottir, Kari Stefansson, andMe Research Team, Unnur Styrkarsdottir, John R B Perry, Andrea Dunaif, Joop Laven, Steve Franks, Cecilia M Lindgren, Corrine K Welt
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007813 (2018)
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose
Externí odkaz:
https://doaj.org/article/c68abd5b52b94dbab11b2cca436008a6
Autor:
M. Geoffrey Hayes, Margrit Urbanek, David A. Ehrmann, Loren L. Armstrong, Ji Young Lee, Ryan Sisk, Tugce Karaderi, Thomas M. Barber, Mark I. McCarthy, Stephen Franks, Cecilia M. Lindgren, Corrine K. Welt, Evanthia Diamanti-Kandarakis, Dimitrios Panidis, Mark O. Goodarzi, Ricardo Azziz, Yi Zhang, Roland G. James, Michael Olivier, Ahmed H. Kissebah, Reproductive Medicine Network, Elisabet Stener-Victorin, Richard S. Legro, Andrea Dunaif
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/393f16795f94454595f713a5d9530c29
Autor:
M. Geoffrey Hayes, Margrit Urbanek, David A. Ehrmann, Loren L. Armstrong, Ji Young Lee, Ryan Sisk, Tugce Karaderi, Thomas M. Barber, Mark I. McCarthy, Stephen Franks, Cecilia M. Lindgren, Corrine K. Welt, Evanthia Diamanti-Kandarakis, Dimitrios Panidis, Mark O. Goodarzi, Ricardo Azziz, Yi Zhang, Roland G. James, Michael Olivier, Ahmed H. Kissebah, Reproductive Medicine Network, Elisabet Stener-Victorin, Richard S. Legro, Andrea Dunaif
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 6: Article number: 7502 (2015); Published: 18 August 2015; Updated: 12 February 2016 In the original version of this Article the genetic locus 8p23.1 was incorrectly referred to as 8p32.1 throughout. For example, in the Abstract
Externí odkaz:
https://doaj.org/article/7b91269778df4eacb9ba97a24129d177
Autor:
Margrit Urbanek, M Geoffrey Hayes, Hoon Lee, Rachel M Freathy, Lynn P Lowe, Christine Ackerman, Nadereh Jafari, Alan R Dyer, Nancy J Cox, David B Dunger, Andrew T Hattersley, Boyd E Metzger, William L Lowe
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32958 (2012)
Since mediators of inflammation are associated with insulin resistance, and the risk of developing diabetes mellitus and gestational diabetes, we hypothesized that genetic variation in members of the inflammatory gene pathway impact glucose levels an
Externí odkaz:
https://doaj.org/article/312ea9c9afbd45fe926fb61a24a6f4fc
Autor:
Kathryn G Ewens, Michelle R Jones, Wendy Ankener, Douglas R Stewart, Margrit Urbanek, Andrea Dunaif, Richard S Legro, Angela Chua, Ricardo Azziz, Richard S Spielman, Mark O Goodarzi, Jerome F Strauss
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16390 (2011)
Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in women. It is also associated with metabolic disturbances that place women at increased risk for obesity and type 2 diabetes. There is strong evidence for familial clu
Externí odkaz:
https://doaj.org/article/5aa4e5c8e7a347be916a2b69a3763120
Autor:
Tia Jackson-Bey, José Colina, Brett C Isenberg, Jonathan Coppeta, Margrit Urbanek, J Julie Kim, Teresa K Woodruff, Joanna E Burdette, Angela Russo
Publikováno v:
Hum Reprod
STUDY QUESTION How does exposure to a testosterone rich environment affect the function and gene expression of human fallopian tube epithelium (hFTE)? SUMMARY ANSWER Elevated testosterone level alters several gene transcripts that regulate cilia expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07bcf604c60210707a040094f135d91
https://doi.org/10.1093/humrep/deaa157
https://doi.org/10.1093/humrep/deaa157
Autor:
Anna O. Basile, Robert J. Carroll, Ky’Era Actkins, Joshua C. Denny, Ian B. Stanaway, Bahram Namjou, Rex L. Chisholm, Yoonjung Yoonie Joo, Kevin Ho, Maureen E. Smith, Jennifer A. Pacheco, Cindy Meun, Tugce Karderi, Margrit Urbanek, Gail P. Jarvik, David R. Crosslin, John B. Harley, Frank D. Mentch, Matthew Jones, Sarah A. Pendergrass, M. Geoffrey Hayes, Abel N. Kho, Felix R. Day, Lea K. Davis, Hakon Hakonarson, Digna R. Velez Edwards, Scott J. Hebbring, Theresa L. Walunas, Marylyn D. Ritchie
Publikováno v:
J Clin Endocrinol Metab
The Journal of clinical endocrinology and metabolism, 105(6), 1918-1936. Endocrine Society
The Journal of clinical endocrinology and metabolism, 105(6), 1918-1936. Endocrine Society
Context As many as 75% of patients with polycystic ovary syndrome (PCOS) are estimated to be unidentified in clinical practice. Objective Utilizing polygenic risk prediction, we aim to identify the phenome-wide comorbidity patterns characteristic of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f404b526c20f81fe1437d5d2146c17
https://doi.org/10.1210/clinem/dgz326
https://doi.org/10.1210/clinem/dgz326
Autor:
Margrit Urbanek, Teresa K. Woodruff, J. Julie Kim, Joanna E. Burdette, Zhenxiao Lu, Teerawat Wiwatpanit, Alina R Murphy
Publikováno v:
J Clin Endocrinol Metab
ContextPolycystic ovary syndrome (PCOS) is a prevalent disorder in reproductive aged women associated with a number of endocrine and metabolic complications, including increased risk of endometrial cancer.ObjectiveTo study the effect of the character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbfaa5b06980f1afcb81b36d16d8320
https://doi.org/10.1210/clinem/dgz100
https://doi.org/10.1210/clinem/dgz100