Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Margrit Hollborn"'
Autor:
Marie-Christin Beer, Heidrun Kuhrt, Leon Kohen, Peter Wiedemann, Andreas Bringmann, Margrit Hollborn
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 848 (2022)
Dedifferentiation and proliferation of retinal pigment epithelial (RPE) cells are characteristics of retinal diseases. Dedifferentiation is likely associated with changes of inwardly rectifying potassium (Kir) channels. The roles of Kir4.2 channels i
Externí odkaz:
https://doaj.org/article/a229cfbf920747e189b2943053ec3843
Autor:
Catharina Busch, Matus Rehak, Margrit Hollborn, Peter Wiedemann, Gerhard K. Lang, Gabriele E. Lang, Armin Wolf, Heidrun L. Deissler
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e06037- (2021)
Contradictory behavior of microvascular retinal endothelial cells (REC) - a reliable in vitro model to study retinal diseases - have recently been reported which might result from cultivating the cells in standard DMEM not optimized for this cell typ
Externí odkaz:
https://doaj.org/article/a1d3b8c65c0542749008b283c0105d77
Autor:
Philipp Prager, Margrit Hollborn, Anja Steffen, Peter Wiedemann, Leon Kohen, Andreas Bringmann
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165653 (2016)
Systemic hypertension is a risk factor of age-related macular degeneration (AMD), a chronic inflammatory disease. Acute hypertension is caused by increased extracellular osmolarity after intake of dietary salt (NaCl). We determined in cultured human
Externí odkaz:
https://doaj.org/article/8664315e4de8434980f8f150c6e5ae07
Autor:
Moritz Veltmann, Margrit Hollborn, Andreas Reichenbach, Peter Wiedemann, Leon Kohen, Andreas Bringmann
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147312 (2016)
BACKGROUND:Although systemic hypertension is a risk factor of age-related macular degeneration, antihypertensive medications do not affect the risk of the disease. One condition that induces hypertension is high intake of dietary salt resulting in in
Externí odkaz:
https://doaj.org/article/be01488ca7b240e99ab7d27d778f1195
Autor:
Stefanie Vogler, Thomas Pannicke, Margrit Hollborn, Antje Grosche, Stephanie Busch, Sigrid Hoffmann, Peter Wiedemann, Andreas Reichenbach, Hans-Peter Hammes, Andreas Bringmann
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e61631 (2014)
BACKGROUND: Retinal degeneration in transgenic rats that express a mutant cilia gene polycystin-2 (CMV-PKD2(1/703)HA) is characterized by initial photoreceptor degeneration and glial activation, followed by vasoregression and neuronal degeneration (F
Externí odkaz:
https://doaj.org/article/81c0ac5eaafa41499fc1e97a57ceb518
Autor:
Margrit Hollborn, Rui Chen, Peter Wiedemann, Andreas Reichenbach, Andreas Bringmann, Leon Kohen
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59603 (2013)
BACKGROUND: Curcumin from turmeric is an ingredient in curry powders. Due to its antiinflammatory, antioxidant and anticarcinogenic effects, curcumin is a promising drug for the treatment of cancer and retinal diseases. We investigated whether curcum
Externí odkaz:
https://doaj.org/article/ac5517028c884b9c9a6682b8955f422f
Autor:
Peter Wiedemann, Andreas Bringmann, Philipp Prager, Fabian Doktor, Margrit Hollborn, Leon Kohen
Publikováno v:
Purinergic Signalling. 14:471-484
Retinal hypoxia is a major condition of the chronic inflammatory disease age-related macular degeneration. Extracellular ATP is a danger signal which is known to activate the NLRP3 inflammasome in various cell systems. We investigated in cultured hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d6c1bb73f344de0c928b05e9f43c49d
https://doi.org/10.1007/s11302-018-9631-6
https://doi.org/10.1007/s11302-018-9631-6
Publikováno v:
Experimental Eye Research. 211:108741
Retinal pigment epithelial (RPE) cells express different subtypes of inwardly rectifying potassium (Kir) channels. We investigated whether human and rat RPE cells express genes of strongly rectifying Kir2 channels. We also determined the hypoxic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ad800e88134ca317ac268abdad5c15
https://doi.org/10.1016/j.exer.2021.108741
https://doi.org/10.1016/j.exer.2021.108741
Publikováno v:
Cytokine & Growth Factor Reviews. 34:43-57
This review summarizes the present knowledge concerning the retinal localization of the nerve growth factor (NGF), its precursor proNGF, and the receptors TrkA and p75NTR in the developing and mature rodent retina. We further discuss the changes in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ffc678624097ab9e40300b37c2f17d
https://doi.org/10.1016/j.cytogfr.2016.11.005
https://doi.org/10.1016/j.cytogfr.2016.11.005
Autor:
Matus Rehak, Armin Wolf, Gabriele E. Lang, Heidrun L. Deissler, Margrit Hollborn, Gerhard K. Lang, Catharina Busch, Peter Wiedemann
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e06037-(2021)
Heliyon
Heliyon
Contradictory behavior of microvascular retinal endothelial cells (REC) - a reliable in vitro model to study retinal diseases - have recently been reported which might result from cultivating the cells in standard DMEM not optimized for this cell typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c340eedf1f8938d47b751aabc2bb5599
https://doi.org/10.1016/j.heliyon.2021.e06037
https://doi.org/10.1016/j.heliyon.2021.e06037