Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Margrete R Hellem"'
Autor:
Jan Roger Olsen, Anne Margrete Oyan, Kari Rostad, Margrete R Hellem, Jie Liu, Lisha Li, David R Micklem, Hallvard Haugen, James B Lorens, Varda Rotter, Xi-Song Ke, Biaoyang Lin, Karl-Henning Kalland
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62547 (2013)
The transcription factor p63 is central for epithelial homeostasis and development. In our model of epithelial to mesenchymal transition (EMT) in human prostate cells, p63 was one of the most down-regulated transcription factors during EMT. We theref
Externí odkaz:
https://doaj.org/article/d7fd1bb4aff245c3a9fcd44b2011fe53
Autor:
Xisong Ke, Anne Margrete Øyan, Emmet McCormack, Karl-Henning Kalland, Mihaela Popa, Wen-Cheng Li, Kari Rostad, Margrete R. Hellem, Yi Qu
Publikováno v:
International Journal of Cancer. 133:544-555
MicroRNAs play critical roles in tumorigenesis and metastasis. Here, we report the dual functions of miR-182 and miR-203 in our previously described prostate cell model. MiR-182 and miR-203 were completely repressed during epithelial to mesenchymal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69ee82e804face8efb90dc22e4e794a5
https://doi.org/10.1002/ijc.28056
https://doi.org/10.1002/ijc.28056
Autor:
Jan Roger Olsen, Margrete R. Hellem, Xisong Ke, Karl-Henning Kalland, Waqas Azeem, Yi Qu, Biaoyang Lin, Kristo Marvyin, Lisha Li, Anne Margrete Øyan, Yaping Hua
Publikováno v:
BMC Cancer
Background Expression of the androgen receptor (AR) is associated with androgen-dependent proliferation arrest and terminal differentiation of normal prostate epithelial cells. Additionally, activation of the AR is required for survival of benign lum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46796a994f1b5c37135ff595221f5827
https://doi.org/10.1186/s12885-016-2453-4
https://doi.org/10.1186/s12885-016-2453-4
Autor:
Margrete R. Hellem, Yi Qu, Biaoyang Lin, Waqas Azeem, Jan Roger Olsen, Karl-Henning Kalland, Anne Margrete Øyan, Kristo Marvyin, Xisong Ke, Yaping Hua, Lisha Li
Publikováno v:
Cancer Research. 76:1824-1824
Background: Expression of the androgen receptor (AR) is associated with androgen-dependent proliferation arrest and terminal differentiation of normal prostate epithelial cells. Additionally, activation of the AR is required for survival of benign lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aad1d95309417124921387726dfc8b6e
https://doi.org/10.1158/1538-7445.am2016-1824
https://doi.org/10.1158/1538-7445.am2016-1824
Autor:
Kristo Marvyin, Yi Qu, Yaping Hua, Waqas Azeem, Xisong Ke, Karl-Henning Kalland, Lisha Li, Jan Roger Olsen, Margrete R. Hellem, Anne Margrete Øyan, Biaoyang Lin
Publikováno v:
Cancer Research. 76:2902-2902
The androgen receptor (AR) transcription factor plays a key role in the development and progression of prostate cancer. Inhibition of its ligand by androgen deprivation therapy (ADT) is consequently the main medical treatment of invasive prostate can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a99ae28063dad0295e1bfc8b64f1be47
https://doi.org/10.1158/1538-7445.am2016-2902
https://doi.org/10.1158/1538-7445.am2016-2902
Autor:
Jan Roger Olsen, Kristo Marvyin, Xisong Ke, Margrete R. Hellem, Karl-Henning Kalland, Anne Margrete Øyan, Biaoyang Lin, Waqas Azeem, Yaping Hua, Yi Qu
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177861 (2017)
PLoS ONE
PLoS ONE
The androgen receptor (AR) transcription factor plays a key role in the development and progression of prostate cancer, as is evident from the efficacy of androgen-deprivation therapy, AR is also the most frequently mutated gene, in castration resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26a7f94845b19a7e7ea3d7cbf0f888d
https://doi.org/10.1371/journal.pone.0177861
https://doi.org/10.1371/journal.pone.0177861
Autor:
Waqas Azeem, Lisha Li, Karl-Henning Kalland, Kristo Marvyin, Margrete R. Hellem, Yi Qu, Yaping Hua, Biaoyang Lin, Xisong Ke, Jan Roger Olsen, Anne Margrete Øyan
Publikováno v:
Cancer Research. 75:79-79
Background: The androgen receptor (AR) transcription factor plays pivotal roles in the development and progression of prostate cancer. AR is activated and maintained throughout prostate cancer progression even in castration-resistant prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edd38d0a6aa6acc07c57c7b5bb064fb0
https://doi.org/10.1158/1538-7445.am2015-79
https://doi.org/10.1158/1538-7445.am2015-79
Autor:
Anne Margrete Øyan, Jan Roger Olsen, David Micklem, Margrete R. Hellem, Kari Rostad, Xisong Ke, Hallvard Haugen, James B. Lorens, Biaoyang Lin, Jie Liu, Varda Rotter, Karl-Henning Kalland, Lisha Li
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62547 (2013)
PLoS ONE
PLoS ONE
The transcription factor p63 is central for epithelial homeostasis and development. In our model of epithelial to mesenchymal transition (EMT) in human prostate cells, p63 was one of the most down-regulated transcription factors during EMT. We theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e024fd91c966df04d6c196162ef2657a
http://europepmc.org/articles/PMC3641034?pdf=render
http://europepmc.org/articles/PMC3641034?pdf=render
Autor:
Yi Qu, Lisha Li, Varda Rotter, Jan Roger Olsen, Margrete R. Hellem, Anne Margrete Øyan, Kari Rostad, Xisong Ke, Kristo Marvyin, Jie Liu, Yaping Hua, Karl-Henning Kalland, Biaoyang Lin
Publikováno v:
Cancer Research. 74:2329-2329
Background: The androgen receptor (AR) is activated and pathogenic in castration resistant prostate cancer (CRPC) due to a variety of escape mechanisms from anti-androgen treatment. The “cell of origin” of prostate cancer is not finally defined,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c380eb109811b014b72bc5037b5f50da
https://doi.org/10.1158/1538-7445.am2014-2329
https://doi.org/10.1158/1538-7445.am2014-2329
Autor:
Xisong Ke, Jie Liu, Kari Rostad, Jan Roger Olsen, Biaoyang Lin, Varda Rotter, Lisha Li, Karl-Henning Kalland, Anne Margrete Øyan, James B. Lorens, Hallvard Haugen, Margrete R. Hellem, David Micklem
Publikováno v:
Cancer Research. 73:1820-1820
Background: p63 is a transcription factor that is central for epithelial homeostasis and development. In our cell culture model of epithelial to mesenchymal transition (EMT) in a human prostate cells, p63 was one of the most down-regulated transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b9a9bfe08062dcedd42fc7cc1fdee6
https://doi.org/10.1158/1538-7445.am2013-1820
https://doi.org/10.1158/1538-7445.am2013-1820