Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Margret Nathan"'
Autor:
Gale Smith, Rama Raghunandan, Yingyun Wu, Ye Liu, Michael Massare, Margret Nathan, Bin Zhou, Hanxin Lu, Sarathi Boddapati, Jingning Li, David Flyer, Gregory Glenn
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50852 (2012)
Respiratory Syncytial Virus (RSV) is an important viral agent causing severe respiratory tract disease in infants and children as well as in the elderly and immunocompromised individuals. The lack of a safe and effective RSV vaccine represents a majo
Externí odkaz:
https://doaj.org/article/0a7aca2c825048ba8fb18a9332825bee
Autor:
Jody Hatch, Denise Courbron, Daniel Baskind, John P. Higgins, Kwan-Ho Roh, John Burd, Hua Jiang, Erica Shane, James Wong, Gale Smith, Diana Chinchilla-Olszar, Mervyn Hamer, Margret Nathan, Malek Masoud, Timothy J. Hahn, Monique Malou-Williams, Ziping Wei, Konnie Taylor, Mike Sowers
Publikováno v:
BioProcessing Journal. 12:4-17
N ovavax reported that, in 28 days following public release of the avian influenza A/Anhui/1/2013 (H7N9) virus gene sequences, its recombinant DNA and baculovirus-Spodoptera frugiperda cell culture-based technology was used to produce a virus-like pa
Autor:
Margret Nathan, Neal Van Hoeven, D. Craig Wright, Terrence M. Tumpey, Gale Smith, Peter Pushko, Jessica A. Belser, Bright Rick, Robin A. Robinson
Publikováno v:
Vaccine. 25:4283-4290
The development of safe and effective vaccines for avian influenza viruses is a priority for pandemic preparedness. Adjuvants improve the efficacy of vaccines and may allow antigen sparing during a pandemic. We have previously shown that influenza vi
Publikováno v:
Molecular Biotechnology. 8:61-77
Reverse transcriptase (RT) is the key enzyme required for conversion of RNA to DNA. Cloning of Moloney murine leukemia virus (MMLV) RT has enable engineering an RT that lacks endogenous RNase H activity. RT catalyzes cDNA synthesis more efficiently i
Autor:
Hanxin Lu, Bin Zhou, Gregory M. Glenn, Margret Nathan, Ye Liu, Sarathi Boddapati, Jingning Li, Yingyun Wu, Gale Smith, Michael J. Massare, Rama Raghunandan, David Flyer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e50852 (2012)
PLoS ONE, Vol 7, Iss 11, p e50852 (2012)
Respiratory Syncytial Virus (RSV) is an important viral agent causing severe respiratory tract disease in infants and children as well as in the elderly and immunocompromised individuals. The lack of a safe and effective RSV vaccine represents a majo
Autor:
Lei Wang, Margret Nathan, Michael J. Massare, Ye V. Liu, Thomas Kort, Dale L. Barnard, Gale Smith
Publikováno v:
Vaccine
SARS-CoV was the cause of the global pandemic in 2003 that infected over 8000 people in 8 months. Vaccines against SARS are still not available. We developed a novel method to produce high levels of a recombinant SARS virus-like particles (VLPs) vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c81dd13a6d408adb021d55a68e0172f
https://europepmc.org/articles/PMC3165014/
https://europepmc.org/articles/PMC3165014/
Autor:
S L Emanuel, N Sarver, Joseph Schlessinger, A Ullrich, Margret Nathan, I. Lax, David R. Hurwitz, S Felder
Publikováno v:
Journal of Biological Chemistry. 266:22035-22043
The binding of epidermal growth factor (EGF) to its cell surface receptor (EGF-R) results in a number of intracellular responses including the activation of the receptor intracellular tyrosine kinase. Receptor oligomerization induced by ligand bindin
Publikováno v:
Transgenic research. 3(6)
A new series of expression vectors, each comprised of the beta-lactoglobulin (BLG) promoter driving one of a variety of human serum albumin (HSA) minigenes or the entire gene, were evaluated for their ability to direct expression of HSA in vitro in C
Autor:
David Givol, Itzhak Dekel, Alexander Faerman, George A. Ricca, Moshe Shani, George H. Searfoss, Margret Nathan, David R. Hurwitz, Itamar Barash
Publikováno v:
Transgenic research. 1(5)
We have tested the feasibility of producing large quantities of human serum albumin (HSA) in the milk of transgenic livestock by generating transgenic mice as a model system. The sheep beta-lactoglobulin (BLG) 5'-regulatory promoter sequences were us
Publikováno v:
DNA. 6:553-564
The bleeding disorder in hemophilia A results from a deficiency or abnormality of Factor VIII (FVIII), a member of the coagulation cascade. FVIII is a large glycoprotein (approximately 350,000 daltons) that is activated by a series of proteolytic cle