Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Margret H Ogmundsdottir"'
Autor:
Francois Singh, Lea Wilhelm, Alan R. Prescott, Kevin Ostacolo, Jin-Feng Zhao, Margret H. Ogmundsdottir, Ian G. Ganley
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
PINK1, mutated in familial forms of Parkinson’s disease, initiates mitophagy following mitochondrial depolarization. However, it is difficult to monitor this pathway physiologically in mice as loss of PINK1 does not alter basal mitophagy levels in
Externí odkaz:
https://doaj.org/article/5b57ed0a9adb48e88193d7ed8114fd86
Autor:
Margret Bessadottir, Mar Egilsson, Eydis Einarsdottir, Iris H Magnusdottir, Margret H Ogmundsdottir, Sesselja Omarsdottir, Helga M Ogmundsdottir
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51296 (2012)
The lichen compound usnic acid (UA) is a lipophilic weak acid that acts as a proton shuttle and causes loss of mitochondrial inner membrane potential. In the current study we show that UA treatment induced the formation of autophagosomes in human can
Externí odkaz:
https://doaj.org/article/e6f87ea2282d4be5b8c90b437b50a4a2
Autor:
Stephanie U. Greer, Jiamin Chen, Margret H. Ogmundsdottir, Carlos Ayala, Billy T. Lau, Richard Glenn C. Delacruz, Imelda T. Sandoval, Sigrun Kristjansdottir, David A. Jones, Derrick S. Haslem, Robin Romero, Gail Fulde, John M. Bell, Jon G. Jonasson, Eirikur Steingrimsson, Hanlee P. Ji, Lincoln D. Nadauld
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Autophagy is a housekeeping mechanism tasked with eliminating misfolded proteins and damaged organelles to maintain cellular homeostasis. Autophagy deficiency results in increased oxidative stress, DNA damage and chronic cellular injury. Amo
Externí odkaz:
https://doaj.org/article/07556fe7ab554218a24d01d6e4b51299
Autor:
Stephanie U. Greer, Jiamin Chen, Margret H. Ogmundsdottir, Carlos Ayala, Billy T. Lau, Richard Glenn C. Delacruz, Imelda T. Sandoval, Sigrun Kristjansdottir, David A. Jones, Derrick S. Haslem, Robin Romero, Gail Fulde, John M. Bell, Jon G. Jonasson, Eirikur Steingrimsson, Hanlee P. Ji, Lincoln D. Nadauld
Publikováno v:
Scientific reports. 12(1)
Autophagy is a housekeeping mechanism tasked with eliminating misfolded proteins and damaged organelles to maintain cellular homeostasis. Autophagy deficiency results in increased oxidative stress, DNA damage and chronic cellular injury. Among the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aedf9b720646e2f12d00fb5113a59b7
https://pubmed.ncbi.nlm.nih.gov/35725745
https://pubmed.ncbi.nlm.nih.gov/35725745
Autor:
Margret H. Ogmundsdottir, Helga Zoega, Sigrun H. Lund, Helga M. Ögmundsdóttir, Anton Pottegård, Oskar Halfdanarson
Publikováno v:
Hálfdánarson, Ó, Pottegård, A, Lund, S H, Ogmundsdottir, M H, Ogmundsdottir, H M & Zoega, H 2020, ' Use of proton pump inhibitors and mortality among Icelandic patients with prostate cancer ', Basic and Clinical Pharmacology and Toxicology, vol. 126, no. 6, pp. 484-491 . https://doi.org/10.1111/bcpt.13379
Proton pump inhibitors (PPIs) are commonly used drugs among cancer patients. Due to conflicting reports on their safety, we aimed to determine whether PPI use is associated with mortality among prostate cancer patients. In this population-based cohor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28edffb5474c591132fac002621efa66
https://doi.org/10.1111/bcpt.13379
https://doi.org/10.1111/bcpt.13379
Autor:
Vivian Pogenberg, Margret H. Ogmundsdottir, Romana Schober, Morlin Milewski, Agnieszka Obarska-Kosinska, Rainer Schindl, Josué Ballesteros-Álvarez, Matthias Wilmanns, Ingibjörg Sigvaldadóttir, Eiríkur Steingrímsson
Publikováno v:
'Nucleic Acids Research ', vol: 48, pages: 934-948 (2020)
Nucleic Acids Research
Nucleic Acids Research
Interrupted dimeric coiled coil segments are found in a broad range of proteins and generally confer selective functional properties such as binding to specific ligands. However, there is only one documented case of a basic-helix–loop–helix leuci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d49e7c385a7315ecd9f13086ade5f3
https://doi.org/10.1093/nar/gkz1104
https://doi.org/10.1093/nar/gkz1104
Autor:
Margret H. Ogmundsdottir, Andrea García-Llorca, Snaefridur Gudmundsdottir Aspelund, Thor Eysteinsson, Eiríkur Steingrímsson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Publisher's version (útgefin grein).
Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and func
Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33336d6171822506fc754a0f9a687c6
http://link.springer.com/article/10.1038/s41598-019-51819-0
http://link.springer.com/article/10.1038/s41598-019-51819-0
Autor:
Phil F. Cheng, Colin Kenny, Ossia M. Eichhoff, Kritika Kirty, Marie de Tayrac, Berglind Osk Einarsdottir, Katrin Möller, Robert A. Cornell, Eiríkur Steingrímsson, Margret H. Ogmundsdottir, Ilse Gerritsen, Valerie Fock, Sara Sigurbjörnsdóttir, Romain Maurice Jacques Lasseur, Philipp Cerny, Mitchell P. Levesque, Erna Magnúsdóttir, E. Elizabeth Patton, Ramile Dilshat, Lionel Larue, Jana Travnickova
Publikováno v:
eLife
eLife, 2021, 10, ⟨10.7554/eLife.63093⟩
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.63093⟩
eLife, Vol 10 (2021)
MITF reprograms the extracellular matrix and focal adhesion in melanoma
eLife, 2021, 10, ⟨10.7554/eLife.63093⟩
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.63093⟩
eLife, Vol 10 (2021)
MITF reprograms the extracellular matrix and focal adhesion in melanoma
The microphthalmia associated transcription factor (MITF) is a critical regulator of melanocyte development and differentiation. It also plays an important role in melanoma where it has been described as a molecular rheostat that, depending on activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdab25a0704ebb828e48fae1ab622ae
https://hal.science/hal-03134824
https://hal.science/hal-03134824
Autor:
Valerie Fock, Romain Maurice Jacques Lasseur, Erna Magnúsdóttir, Margret H. Ogmundsdottir, Mitchell P. Levesque, Robert A. Cornell, Ossia M. Eichhoff, E. Elizabeth Patton, Eiríkur Steingrímsson, Sara Sigurbjörnsdóttir, Katrin Möller, Berglind Osk Einarsdottir, Ilse Gerritsen, Ramile Dilshat, Lionel Larue, Marie de Tayrac, Jana Travnickova, Phil F. Cheng, Colin Kenny, Philipp Cerny, Kritika Kirty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84159e8a30c9a5ec48bbed32b5796d0
https://doi.org/10.7554/elife.63093.sa2
https://doi.org/10.7554/elife.63093.sa2
Autor:
Lionel Larue, Eiríkur Steingrímsson, Valerie Fock, Ramile Dilshat, Katrin Möller, Margret H. Ogmundsdottir, Ludwig Karl, Josué Ballesteros-Álvarez
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238546 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238546 (2020)
Publisher's version (útgefin grein)
The MITF, TFEB, TFE3 and TFEC (MiT-TFE) proteins belong to the basic helix-loop-helix family of leucine zipper transcription factors. MITF is crucial for melanocyte development and differentiation, and has be
The MITF, TFEB, TFE3 and TFEC (MiT-TFE) proteins belong to the basic helix-loop-helix family of leucine zipper transcription factors. MITF is crucial for melanocyte development and differentiation, and has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6b41148a6e8c302e85ef61a3a8c248
http://europepmc.org/articles/PMC7470386
http://europepmc.org/articles/PMC7470386