Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Margreet C M Vissers"'
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186115 (2017)
The inflammatory and metabolic derangements of obesity in pregnant women generate an adverse intrauterine environment, increase pregnancy complications and adverse fetal outcomes and program the fetus for obesity and metabolic syndrome in later life.
Externí odkaz:
https://doaj.org/article/f53ad9d5747e4c64ba8a86017638d2e2
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171206 (2017)
This study tested the psychological benefits of a 14-day preregistered clinical intervention to increase fruit and vegetable (FV) consumption in 171 low-FV-consuming young adults (67% female, aged 18-25). Participants were randomly assigned into a di
Externí odkaz:
https://doaj.org/article/485843f675014926bb617b1b675f4a3b
Autor:
Caroline eKuiper, Margreet C M Vissers
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Ascorbate is a specific cofactor for a large family of enzymes known as the Fe- and 2-oxoglutarate-dependent dioxygenases. These enzymes are found throughout biology and catalyse the addition of a hydroxyl group to various substrates. The proline hyd
Externí odkaz:
https://doaj.org/article/9ca834cd602c4b89a50a499c47974170
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Cancer patients commonly experience a number of symptoms of disease progression and the side effects of radiation therapy and adjuvant chemotherapy, which adversely impact on their quality of life. Fatigue is one of the most common and debilitating s
Externí odkaz:
https://doaj.org/article/b44f772428c841f3bf2b9fb633e9aa62
Autor:
Caroline eKuiper, Gabi eDachs, Delwyn eMunn, Margaret eCurrie, Bridget eRobinson, John Frederick Pearson, Margreet C M Vissers
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Ascorbate is a co-factor for the hydroxylases that regulate the transcription factor hypoxia-inducible factor (HIF)-1, which provides cancer cells with a metabolic and survival advantage in the hypoxic environment of solid tumors. However, whether as
Externí odkaz:
https://doaj.org/article/2f9cf96442bd4d98a7f6dc5c2cdb49aa
Autor:
Ben Topham, Millie de Vries, Maria Nonis, Rebecca van Berkel, Juliet M. Pullar, Nicholas J. Magon, Margreet C. M. Vissers, Margaret J. Currie, Bridget A. Robinson, David Gibbs, Abel Ang, Gabi U. Dachs
Publikováno v:
Epigenomes, Vol 8, Iss 2, p 17 (2024)
The treatment of metastatic melanoma has been revolutionised by immunotherapy, yet a significant number of patients do not respond, and many experience autoimmune adverse events. Associations have been reported between patient outcome and monocyte su
Externí odkaz:
https://doaj.org/article/f0a8556d4d2b4ffcbb4e8fb7b96cfc9d
Autor:
Rebekah L. I. Crake, Eleanor R. Burgess, George A. R. Wiggins, Nicholas J. Magon, Andrew B. Das, Margreet C. M. Vissers, Helen R. Morrin, Janice A. Royds, Tania L. Slatter, Bridget A. Robinson, Elisabeth Phillips, Gabi U. Dachs
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Gliomas are incurable brain cancers with poor prognosis, with epigenetic dysregulation being a distinctive feature. 5-hydroxymethylcytosine (5-hmC), an intermediate generated in the demethylation of 5-methylcytosine, is present at reduced le
Externí odkaz:
https://doaj.org/article/29bbf00353694620bd5b46e7983ef037
Publikováno v:
Nutrients, Vol 16, Iss 3, p 369 (2024)
Our previous work in guinea pigs revealed that low vitamin C intake during preconception and pregnancy adversely affects fertility, pregnancy outcomes, and foetal and neonatal growth in a sex-dependent manner. To investigate the long-term impact on o
Externí odkaz:
https://doaj.org/article/e4dd4c0f2bd14329998d8640be8c47ad
Autor:
Eleanor R. Burgess, Rebekah L. I. Crake, Elisabeth Phillips, Helen R. Morrin, Janice A. Royds, Tania L. Slatter, George A. R. Wiggins, Margreet C. M. Vissers, Bridget A. Robinson, Gabi U. Dachs
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Glioblastoma multiforme is a challenging disease with limited treatment options and poor survival. Glioblastoma tumours are characterised by hypoxia that activates the hypoxia inducible factor (HIF) pathway and controls a myriad of genes that drive c
Externí odkaz:
https://doaj.org/article/f59593b61a444e2e93b8171168297f54
Autor:
Tamlin S. Conner, Benjamin D. Fletcher, Jillian J. Haszard, Juliet M. Pullar, Emma Spencer, Louise A. Mainvil, Margreet C. M. Vissers
Publikováno v:
Nutrients, Vol 12, Iss 9, p 2898 (2020)
Consumption of vitamin C-rich fruits and vegetables has been associated with greater feelings of vitality. However, these associations have rarely been tested in experimental trials. The aim of the current study was to test the effects of eating a vi
Externí odkaz:
https://doaj.org/article/6b5b3c6696dd4893be18d82da17396c8