Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Margot Zöller"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-7 (2024)
Externí odkaz:
https://doaj.org/article/1ed8f49094cb41399c3cd3bb9f2a0fff
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/df3c4f145402434fa745de36aa3cd270
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-20 (2019)
Abstract Background Cancer-initiating cell (CIC) exosomes (CIC-TEX) are suggested reprogramming Non-CIC. Mode of message transfer and engagement of CIC-markers being disputed, we elaborated the impact of CD44v6 and Tspan8 on the response of Non-CIC.
Externí odkaz:
https://doaj.org/article/57476ca358104cc89e029ab94533784b
Publikováno v:
Translational Oncology, Vol 12, Iss 2, Pp 191-199 (2019)
AIM: Transfer of exosomes (Exo) miRNA was described interfering with tumor progression. We here explored for claudin7 (cld7) and EpCAM (EpC), cancer-initiating-cell markers in colorectal and pancreatic cancer, the efficacy of Exo loading with miRNA a
Externí odkaz:
https://doaj.org/article/3296ede47048434088d035b0b178f2aa
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-23 (2018)
Abstract Background The tetraspanins Tspan8 and CD151 promote metastasis, exosomes (Exo) being suggested to be important in the crosstalk between tumor and host. The contribution of Tspan8 and CD151 to host versus tumor-derived exosome (TEX) activiti
Externí odkaz:
https://doaj.org/article/715e889d14e4487e83c52b4ce79a387c
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Identification of immunogenic tumor antigens that are efficiently processed and delivered by dendritic cells to prime the immune system and to induce an appropriate immune response is a research hotspot in the field of cancer vaccine development. Hig
Externí odkaz:
https://doaj.org/article/a73f372d436c4ceb92810ca4d122b058
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Metastasis is the main cause of high pancreatic cancer (PaCa) mortality and trials dampening PaCa mortality rates are not satisfying. Tumor progression is driven by the crosstalk between tumor cells, predominantly cancer-initiating cells (CIC), and s
Externí odkaz:
https://doaj.org/article/0cf416ae71534afbb4fcaf2f8108cc39
Publikováno v:
Cells, Vol 9, Iss 2, p 319 (2020)
Tumor cell-derived extracellular vesicles (TEX) expressing tetraspanin Tspan8-alpha4/beta1 support angiogenesis. Tspan8-alpha6/beta4 facilitates lung premetastatic niche establishment. TEX-promoted target reprogramming is still being disputed, we exp
Externí odkaz:
https://doaj.org/article/92c9ddd219b04650840ec9bc3ce30560
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Metastasis is the leading cause of cancer death, tumor progression proceeding through emigration from the primary tumor, gaining access to the circulation, leaving the circulation, settling in distant organs and growing in the foreign environment. Th
Externí odkaz:
https://doaj.org/article/1cd5fe3cbdc94bd788649eb24ef8d563
Autor:
Margot Zöller, Kun Zhao, Natalia Kutlu, Nathalie Bauer, Jan Provaznik, Thilo Hackert, Martina Schnölzer
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The treatment of autoimmune diseases still poses a major challenge, frequently relying on non-specific immunosuppressive drugs. Current efforts aim at reestablishing self tolerance using immune cells with suppressive activity like the regulatory T ce
Externí odkaz:
https://doaj.org/article/a2627228eb1745b7a9171e7de8538fec