Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Margot Zevon"'
Autor:
Mark C. Pierce, Whitney Banach-Petrosky, Shravani Barkund, Yang Sheng, Richard E. Riman, Xinyu Zhao, Harini Kantamneni, Laura M. Higgins, Shridar Ganesan, Lucas H McCabe, Michael J Donzanti, Charles M. Roth, Margot Zevon, Vidya Ganapathy, Prabhas V. Moghe, Mei Chee Tan
Publikováno v:
Nature biomedical engineering
The identification and molecular profiling of early metastases remains a major challenge in cancer diagnostics and therapy. Most in vivo imaging methods fail to detect small cancerous lesions, a problem that is compounded by the distinct physical and
Autor:
Prabhas V. Moghe, Mei Chee Tan, Derek Adler, Yang Sheng, Charles M. Roth, Harini Kantamneni, Mark C. Pierce, Richard E. Riman, Paul Kim, Marco Mingozzi, Margot Zevon, Vidya Ganapathy
Publikováno v:
Small. 11:6347-6357
Realizing the promise of precision medicine in cancer therapy depends on identifying and tracking of cancerous growths in order to maximize treatment options and improve patient outcomes. However, this goal of early detection remains unfulfilled by c
Autor:
Margot Zevon, Dominik J. Naczynski, Prabhas V. Moghe, Suzie Chen, Charles M. Roth, Mingjie Cui, Larisa Sheihet, Craig K. Griffith, Izmarie Poventud-Fuentes
Publikováno v:
Advanced Healthcare Materials. 2:1236-1245
Current cancer therapies are challenged by weakly soluble drugs and by drug combinations that exhibit non-uniform biodistribution and poor bioavailability. In this study, we have presented a new platform of advanced healthcare materials based on albu
Autor:
Mark C. Pierce, Charles M. Roth, Prabhas V. Moghe, Marco Mingozzi, Laura M. Higgins, Vidya Ganapathy, Richard E. Riman, Harini Kantamneni, Margot Zevon
Publikováno v:
SPIE Proceedings.
Success of personalized medicine in cancer therapy depends on the ability to identify and molecularly phenotype tumors. Current clinical imaging techniques cannot be integrated with precision molecular medicine at the level of single cells or microle
Autor:
Mei Chee Tan, Mark C. Pierce, Yang Sheng, Vidya Ganapathy, Charles M. Roth, Harini Kantamneni, Margot Zevon, Richard E. Riman, Laura M. Higgins, Prabhas V. Moghe
Publikováno v:
Biomedical Optics 2016.
We describe the development and testing of a line-scanning confocal microscope and integrated confocal / optical coherence tomography system for imaging biological cells and tissues labeled with molecularly-targeted rare-earth-doped nanocomposites.
Autor:
Laura M. Higgins, Vidya Ganapathy, Mark C. Pierce, Yang Sheng, Mei Chee Tan, Margot Zevon, Prabhas V. Moghe, Richard E. Riman, Charles M. Roth
Publikováno v:
Journal of biomedical optics. 20(11)
Rare-earth (RE) doped nanocomposites emit visible luminescence when illuminated with continuous wave near-infrared light, making them appealing candidates for use as contrast agents in biomedical imaging. However, the emission lifetime of these mater
Autor:
Marco Mingozzi, Prabhas V. Moghe, Philip Hu, Mark C. Pierce, Charles M. Roth, Laura M. Higgins, Vidya Ganapathy, Margot Zevon, Richard E. Riman
Publikováno v:
Molecular-Guided Surgery: Molecules, Devices, and Applications.
We report the design, calibration, and testing of a pre-clinical small animal imaging platform for use with short-wave infrared (SWIR) emitting contrast agents. Unlike materials emitting at visible or near-infrared wavelengths, SWIR-emitting agents r
Autor:
Nan Yao, Nathalie M. Pinkerton, Derek Adler, Patrick J. Sinko, Ruobing Wang, Shike Li, Carlos Rinaldi, Theodore S. Wolfson, Carlos Pacheco, Dayuan Gao, Michael J. Therien, Robert K. Prud'homme, Marian E. Gindy, Robert F. Pagels, Victoria L. Calero-DdelC, Margot Zevon
Publikováno v:
Advanced healthcare materials. 4(9)
Magnetic resonance imaging (MRI)- and near-infrared (NIR)-active, multimodal composite nanocarriers (CNCs) are prepared using a simple one-step process, flash nanoprecipitation (FNP). The FNP process allows for the independent control of the hydrodyn
Autor:
Suzie Chen, Richard E. Riman, Prabhas V. Moghe, Brian A. Wall, Anthony Kulesa, Margot Zevon, Charles M. Roth, Mei Chee Tan, Dominik J. Naczynski, Jesse Kohl
Publikováno v:
Nature communications
The extension of in vivo optical imaging for disease screening and image-guided surgical interventions requires brightly emitting, tissue-specific materials that optically transmit through living tissue and can be imaged with portable systems that di
Autor:
Derek Adler, Paul Kim, Prabhas V. Moghe, Mark C. Pierce, Harini Kantamneni, Marco Mingozzi, Vidya Ganapathy, Margot Zevon, Richard E. Riman, Charles M. Roth
Publikováno v:
Cancer Research. 75:1482-1482
Metastatic cancer is the leading cause of almost 90% of cancer-related deaths. Early detection of metastatic lesions in breast cancer would lead to judicious therapeutic choices in the management of the disease. Current clinical imaging techniques ar