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Autor:
Hassiba Bouktit, C. Méni, Marine Madrange, Elisa Bayard, Laurent Frenzel, Michel Arock, Olivier Hermine, Christine Bodemer, Leila Maouche-Chretien, Sylvie Fraitag, Ulrich Rüther, Margot Tissandier, Laura Polivka, Anne-Florence Collange, Julien Rossignol, Mélanie Parisot, Christina Gougoula, Rachel Rignault, Smail Hadj-Rabia, Julie Bruneau, Brigitte Bader-Meunier, Nicolas Cagnard, Cristina Bulai Livideanu, Veronique Parietti, Erinn Soucie, Camille Laurent, Ludovic Lhermitte, Patrice Dubreuil, Danielle Canioni, Mélanie Féroul
Publikováno v:
Blood. 138:2396-2407
Mastocytosis is a heterogeneous disease characterized by an abnormal accumulation of mast cells (MCs) in 1 or several organs. Although a somatic KIT D816V mutation is detected in ∼85% of patients, attempts to demonstrate its oncogenic effect alone