Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Margot Morabito"'
Autor:
Laura Bencheikh, M’Boyba Khadija Diop, Julie Rivière, Aygun Imanci, Gerard Pierron, Sylvie Souquere, Audrey Naimo, Margot Morabito, Michaël Dussiot, Frédéric De Leeuw, Camille Lobry, Eric Solary, Nathalie Droin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Receptor tyrosine kinases localize to the cell surface and have been suggested to also have nuclear function. Here the authors provide evidence that Colony Stimulating Factor-1 Receptor (CSF-1R) migrates to the nucleus upon CSF-1 stimulation in monoc
Externí odkaz:
https://doaj.org/article/087012bf40e543c99b57671485f865ff
Autor:
Dorothée Selimoglu-Buet, Julie Rivière, Hussein Ghamlouch, Laura Bencheikh, Catherine Lacout, Margot Morabito, M’boyba Diop, Guillaume Meurice, Marie Breckler, Aurélie Chauveau, Camille Debord, Franck Debeurme, Raphael Itzykson, Nicolas Chapuis, Christophe Willekens, Orianne Wagner-Ballon, Olivier A. Bernard, Nathalie Droin, Eric Solary
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
A decrease in the fraction of non-classical monocytes is a hallmark of chronic myelomonocytic leukaemia. Taking advantage of this abnormal situation, the authors identify a mechanistic link between miR-150 and TET3 as being involved in monocyte subse
Externí odkaz:
https://doaj.org/article/5d55187610e84c0189ca6173abd8c67a
Autor:
Raphael Itzykson, Valeria Santini, Sylvain Thepot, Lionel Ades, Cendrine Chaffaut, Aristoteles Giagounidis, Margot Morabito, Nathalie Droin, Michael Lübbert, Rosa Sapena, Stanislas Nimubona, Jean Goasguen, Eric Wattel, Gina Zini, Jose Miguel Torregrosa Diaz, Ulrich Germing, Anna Maria Pelizzari, Sophie Park, Nadja Jaekel, Georgia Metzgeroth, Francesco Onida, Robert Navarro, Andrea Patriarca, Aspasia Stamatoullas, Katharina Götze, Martin Puttrich, Sandra Mossuto, Eric Solary, Silke Gloaguen, Sylvie Chevret, Fatiha Chermat, Uwe Platzbecker, Pierre Fenaux
Publikováno v:
Journal of Clinical Oncology. 41:1888-1897
PURPOSE Hydroxyurea (HY) is a reference treatment of advanced myeloproliferative neoplasms. We conducted a randomized phase III trial comparing decitabine (DAC) and HY in advanced myeloproliferative chronic myelomonocytic leukemias (CMML). PATIENTS A
Autor:
Sihem Tarfi, Bouchra Badaoui, Nicolas Freynet, Margot Morabito, Jeffie Lafosse, Andréa Toma, Gabriel Etienne, Jean-Baptiste Micol, Ivan Sloma, Pierre Fenaux, Eric Solary, Dorothée Selimoglu-Buet, Orianne Wagner-Ballon
Publikováno v:
Haematologica, Vol 105, Iss 4 (2020)
Externí odkaz:
https://doaj.org/article/0b18a704ee77422eb811515d5f645bfe
Autor:
Yanyan Zhang, Liang He, Dorothée Selimoglu-Buet, Chloe Jego, Margot Morabito, Christophe Willekens, M'boyba Khadija Diop, Patrick Gonin, Valérie Lapierre, Nathalie Droin, Eric Solary, Fawzia Louache
Publikováno v:
Blood Advances, Vol 1, Iss 14, Pp 972-979 (2017)
Abstract: Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder that typically associates with mutations in epigenetic, splicing, and signaling genes. Genetically modified mouse models only partially recapitulate the dis
Externí odkaz:
https://doaj.org/article/66dbe88188da4911846accf2d6be9a8a
Autor:
Jane Merlevede, Nathalie Droin, Tingting Qin, Kristen Meldi, Kenichi Yoshida, Margot Morabito, Emilie Chautard, Didier Auboeuf, Pierre Fenaux, Thorsten Braun, Raphael Itzykson, Stéphane de Botton, Bruno Quesnel, Thérèse Commes, Eric Jourdan, William Vainchenker, Olivier Bernard, Noemie Pata-Merci, Stéphanie Solier, Velimir Gayevskiy, Marcel E. Dinger, Mark J. Cowley, Dorothée Selimoglu-Buet, Vincent Meyer, François Artiguenave, Jean-François Deleuze, Claude Preudhomme, Michael R. Stratton, Ludmil B. Alexandrov, Eric Padron, Seishi Ogawa, Serge Koscielny, Maria Figueroa, Eric Solary
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Chronic myelomonocytic leukaemia is treated with agents that modify DNA methylation but whether they have direct cytotoxic effects is unclear. Here, the authors show that cells from treated patients show marked methylation changes without altered som
Externí odkaz:
https://doaj.org/article/3d387d13bd0349019c8a2486e3d50c61
Autor:
Laurence Kraus-Berthier, Lucie Laplane, Véronique Saada, Céline Berthon, Maria E. Figueroa, Bouchra Badaoui, Margaux Sevin, Franck Debeurme, Eric Padron, Thorsten Braun, Qin Yang, Nathalie Droin, Raphael Itzykson, Guido Kroemer, Dorothée Selimoglu-Buet, Eric Solary, Oliver Kepp, Margot Morabito, Alix Derreal, Hannah Newman, Sylvain Thepot, Gabriel Etienne, Miguel Torres-Martin, Sébastien Banquet, Severine Badel, Orianne Wagner-Ballon, Pierre Fenaux
Publikováno v:
Blood
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩
Blood, American Society of Hematology, 2021, 137 (24), pp.3390-3402. ⟨10.1182/blood.2020008729⟩
Mouse models of chronic myeloid malignancies suggest that targeting mature cells of the malignant clone disrupts feedback loops that promote disease expansion. Here, we show that in chronic myelomonocytic leukemia (CMML), monocytes that accumulate in
Autor:
Dorothée Selimoglu-Buet, Margot Morabito, Bouchra Badaoui, Violaine Tran Quang, Sihem Tarfi, Matthieu Duchmann, Nicolas Freynet, Ivan Sloma, Eric Solary, Matthieu Jestin, Orianne Wagner-Ballon, Nathalie Droin, Pierre Fenaux, Groupe Francophone des Myélodysplasies, Mathieu Leclerc, Sébastien Maury
Publikováno v:
Leukemia. 35:893-896
Autor:
Ivan Sloma, Eric Solary, Andrea Toma, Gabriel Etienne, Nicolas Freynet, Dorothée Selimoglu-Buet, Sihem Tarfi, Margot Morabito, Jeffie Lafosse, Orianne Wagner-Ballon, Pierre Fenaux, Bouchra Badaoui, Jean-Baptiste Micol
Publikováno v:
Haematologica. 105:e147-e152
Autor:
Matthieu, Jestin, Sihem, Tarfi, Matthieu, Duchmann, Bouchra, Badaoui, Nicolas, Freynet, Violaine, Tran Quang, Ivan, Sloma, Nathalie, Droin, Margot, Morabito, Mathieu, Leclerc, Sébastien, Maury, Pierre, Fenaux, Eric, Solary, Dorothée, Selimoglu-Buet, Orianne, Wagner-Ballon, A, Renneville
Publikováno v:
Leukemia. 35(3)