Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Margot M. Ip"'
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 5, Pp 985-994 (2008)
Conjugated linoleic acid (CLA) inhibits rat mammary carcinogenesis, in part by inducing apoptosis of preneoplastic and neoplastic mammary epithelial cells. The current study focused on the mechanism by which apoptosis is induced. In TM4t mammary tumo
Externí odkaz:
https://doaj.org/article/fb3baf72bc6c4a8eb2cba37b284d0ed6
Supplementary Data from Tumor necrosis factor deficiency inhibits mammary tumorigenesis and a tumor necrosis factor neutralizing antibody decreases mammary tumor growth in neu/erbB2 transgenic mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d6e549d763c03b4b3385634a5cf8a8
https://doi.org/10.1158/1535-7163.22486007.v1
https://doi.org/10.1158/1535-7163.22486007.v1
Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine that is synthesized and secreted by cells of the immune system, as well as by certain epithelia and stroma. Based on our previous studies demonstrating TNF-stimulated proliferation of normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5946d9e637b1e92d7c6808722995851
https://doi.org/10.1158/1535-7163.c.6532184.v1
https://doi.org/10.1158/1535-7163.c.6532184.v1
Autor:
Margot M. Ip, Yung-Chung Hsu
Publikováno v:
Cellular Signalling. 23:2013-2020
Conjugated linoleic acid (CLA) has shown chemopreventive activity in several tumorigenesis models, in part through induction of apoptosis. We previously demonstrated that the t10,c12 isomer of CLA induced apoptosis of TM4t mouse mammary tumor cells t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db93e3ec951bed83b79684d058665bea
https://doi.org/10.1016/j.cellsig.2011.07.015
https://doi.org/10.1016/j.cellsig.2011.07.015
Publikováno v:
Cellular Signalling. 22:590-599
Conjugated linoleic acid (CLA) inhibits tumorigenesis and tumor growth in most model systems, an effect mediated in part by its pro-apoptotic activity. We previously showed that trans-10,cis-12 CLA induced apoptosis of p53-mutant TM4t mouse mammary t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ba4d3f999e30b62fe5afd97245f108
https://doi.org/10.1016/j.cellsig.2009.11.011
https://doi.org/10.1016/j.cellsig.2009.11.011
Publikováno v:
Breast Cancer Research and Treatment. 115:43-50
Inactivation of tumor suppressor p53 is one of the most frequent events in cancer. Unlike many other cancers, however, p53 gene mutations are infrequent in breast cancers, as about 80% of breast tumors contain wild type p53. The mechanisms underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4046456d1f6ee19e089ee0cd930b8a6f
https://doi.org/10.1007/s10549-008-0044-z
https://doi.org/10.1007/s10549-008-0044-z
Autor:
Sibel Oflazoglu McGee, Margot M. Ip, Dietrich W. Kuhlmann, Patricia A. Masso-Welch, Joshua S. Russell
Publikováno v:
The Journal of Nutrition. 137:1200-1207
Conjugated linoleic acid (CLA) is a dietary chemopreventive agent that induces apoptosis in the mammary adipose vascular endothelium and decreases mammary brown adipose tissue (BAT) and white adipose tissue (WAT). To determine onset and extent of str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::571e92c98de483297781e679bf5cb70d
https://doi.org/10.1093/jn/137.5.1200
https://doi.org/10.1093/jn/137.5.1200
Publikováno v:
Endocrinology. 148:268-278
Nuclear factor kappaB (NFkappaB) plays an important role in mammary gland development and breast cancer. We previously demonstrated that TNF stimulates growth of mammary epithelial cells (MEC) in a physiologically relevant three-dimensional primary c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18524aff9fa0688fc6db69100fdfce3f
https://doi.org/10.1210/en.2006-0500
https://doi.org/10.1210/en.2006-0500
Autor:
Susan E. McCann, Clement Ip, Margot M. Ip, Michelle K. McGuire, Paola Muti, Stephen B. Edge, Maurizio Trevisan, Jo L. Freudenheim
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 13:1480-1484
Specific fatty acids may have differential effects on breast cancer etiology. Animal studies have suggested that conjugated linoleic acids (CLA), a group of fatty acids found predominantly in dairy products and the meat of ruminants, have potent anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99625d5b98a43dfa2ca389d6ca84c15b
https://doi.org/10.1158/1055-9965.1480.13.9
https://doi.org/10.1158/1055-9965.1480.13.9
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia. 8:103-118
Conjugated linoleic acid (CLA), found naturally in dairy products and ruminant meats, refers to isomers of octadecadienoic acid with conjugated double bonds. CLA inhibits both DMBA- and NMU-induced rat mammary carcinogenesis, and its antitumor effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b1874626358f426eed416576aa172b
https://doi.org/10.1023/a:1025739506536
https://doi.org/10.1023/a:1025739506536