Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Margot Lawton"'
Autor:
Sarah M. DeNucci, Ming Tong, Lisa Longato, Margot Lawton, Mashiko Setshedi, Rolf I. Carlson, Jack R. Wands, Suzanne M. de la Monte
Publikováno v:
Gastroenterology Research and Practice, Vol 2010 (2010)
The finding of more severe steatohepatitis in alcohol fed Long Evans (LE) compared with Sprague Dawley (SD) and Fisher 344 (FS) rats prompted us to determine whether host factors related to alcohol metabolism, inflammation, and insulin/IGF signaling
Externí odkaz:
https://doaj.org/article/06123ee00d704a0ab44ed004aec96910
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 3, Iss 5, Pp 347-356 (2010)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Aspartyl-(Asparaginyl)-β-Hydroxylase (AAH ) promotes cell motility by hydroxylating Notch. Insulin and insulin-like growth factor, type 1 (IGF-I) stimulate AAH through Erk MAP K and phosphoinositol-3-kinase-Akt (PI3K-Akt). However, hypoxia/oxidative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046d5e121ad131dedb24e3682f41753e
https://doaj.org/article/ae70c5a9896042c0bd954a17e0b451c6
https://doaj.org/article/ae70c5a9896042c0bd954a17e0b451c6
Autor:
Ping Jiao, Suzanne M. de la Monte, Jack R. Wands, Lascelles E. Lyn-Cook, Lisa Longato, Ming Tong, Elizabeth Silbermann, Margot Lawton, Haiyan Xu, Princess Mark
Publikováno v:
Journal of Alzheimer's Disease. 16:715-729
Obesity, type 2 diabetes mellitus (T2DM), and non-alcoholic steatohepatitis (NASH) can be complicated by cognitive impairment and neurodegeneration. Experimentally, high fat diet (HFD)-induced obesity with T2DM causes mild neurodegeneration with brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828b9aa9ba8a430f601df10156858fed
https://doi.org/10.3233/jad-2009-0984
https://doi.org/10.3233/jad-2009-0984
Autor:
Ming, Tong, Alexander, Neusner, Lisa, Longato, Margot, Lawton, Jack R, Wands, Suzanne M, de la Monte
Publikováno v:
Journal of Alzheimer's disease : JAD. 17(4)
The current epidemics of type 2 diabetes mellitus (T2DM), non-alcoholic steatohepatitis (NASH), and Alzheimer's disease (AD) all represent insulin-resistance diseases. Previous studies showed that streptozotocin, a nitrosamine-related com-pound, caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1972c39646a21aa27dec44da95d1780
https://pubmed.ncbi.nlm.nih.gov/20387270
https://pubmed.ncbi.nlm.nih.gov/20387270
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 54 (2009)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background The current epidemics of type 2 diabetes mellitus (T2DM), non-alcoholic steatohepatitis (NASH), and Alzheimer's disease (AD) all represent insulin-resistance diseases. Previous studies linked insulin resistance diseases to high fat diets o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741bc94cdd6d1164c14377efb4303e6c
http://www.molecularneurodegeneration.com/content/4/1/54
http://www.molecularneurodegeneration.com/content/4/1/54
Autor:
Mashiko Setshedi, Margot Lawton, Lisa Longato, Jack R. Wands, Suzanne M. de la Monte, Ming Tong, Rolf I. Carlson, Sarah M. DeNucci
Publikováno v:
Gastroenterology Research and Practice
Gastroenterology Research and Practice, Vol 2010 (2010)
Gastroenterology Research and Practice, Vol 2010 (2010)
The finding of more severe steatohepatitis in alcohol fed Long Evans (LE) compared with Sprague Dawley (SD) and Fisher 344 (FS) rats prompted us to determine whether host factors related to alcohol metabolism, inflammation, and insulin/IGF signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d444695d28618ea674145d0cdb74dad6
https://pubmed.ncbi.nlm.nih.gov/20814553
https://pubmed.ncbi.nlm.nih.gov/20814553
Publikováno v:
Journal of Alzheimer's disease : JAD. 17(3)
Nitrosamines mediate their mutagenic effects by causing DNA damage, oxidative stress, lipid peroxidation, and pro-inflammatory cytokine activation, which lead to increased cellular degeneration and death. However, the very same pathophysiological pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09da1b473f91f4592093b6841fb2da03
https://pubmed.ncbi.nlm.nih.gov/20413869
https://pubmed.ncbi.nlm.nih.gov/20413869