Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Margot Lawton"'
Autor:
Sarah M. DeNucci, Ming Tong, Lisa Longato, Margot Lawton, Mashiko Setshedi, Rolf I. Carlson, Jack R. Wands, Suzanne M. de la Monte
Publikováno v:
Gastroenterology Research and Practice, Vol 2010 (2010)
The finding of more severe steatohepatitis in alcohol fed Long Evans (LE) compared with Sprague Dawley (SD) and Fisher 344 (FS) rats prompted us to determine whether host factors related to alcohol metabolism, inflammation, and insulin/IGF signaling
Externí odkaz:
https://doaj.org/article/06123ee00d704a0ab44ed004aec96910
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 3, Iss 5, Pp 347-356 (2010)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Aspartyl-(Asparaginyl)-β-Hydroxylase (AAH ) promotes cell motility by hydroxylating Notch. Insulin and insulin-like growth factor, type 1 (IGF-I) stimulate AAH through Erk MAP K and phosphoinositol-3-kinase-Akt (PI3K-Akt). However, hypoxia/oxidative
Autor:
Ping Jiao, Suzanne M. de la Monte, Jack R. Wands, Lascelles E. Lyn-Cook, Lisa Longato, Ming Tong, Elizabeth Silbermann, Margot Lawton, Haiyan Xu, Princess Mark
Publikováno v:
Journal of Alzheimer's Disease. 16:715-729
Obesity, type 2 diabetes mellitus (T2DM), and non-alcoholic steatohepatitis (NASH) can be complicated by cognitive impairment and neurodegeneration. Experimentally, high fat diet (HFD)-induced obesity with T2DM causes mild neurodegeneration with brai
Autor:
Ming, Tong, Alexander, Neusner, Lisa, Longato, Margot, Lawton, Jack R, Wands, Suzanne M, de la Monte
Publikováno v:
Journal of Alzheimer's disease : JAD. 17(4)
The current epidemics of type 2 diabetes mellitus (T2DM), non-alcoholic steatohepatitis (NASH), and Alzheimer's disease (AD) all represent insulin-resistance diseases. Previous studies showed that streptozotocin, a nitrosamine-related com-pound, caus
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 54 (2009)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background The current epidemics of type 2 diabetes mellitus (T2DM), non-alcoholic steatohepatitis (NASH), and Alzheimer's disease (AD) all represent insulin-resistance diseases. Previous studies linked insulin resistance diseases to high fat diets o
Autor:
Mashiko Setshedi, Margot Lawton, Lisa Longato, Jack R. Wands, Suzanne M. de la Monte, Ming Tong, Rolf I. Carlson, Sarah M. DeNucci
Publikováno v:
Gastroenterology Research and Practice
Gastroenterology Research and Practice, Vol 2010 (2010)
Gastroenterology Research and Practice, Vol 2010 (2010)
The finding of more severe steatohepatitis in alcohol fed Long Evans (LE) compared with Sprague Dawley (SD) and Fisher 344 (FS) rats prompted us to determine whether host factors related to alcohol metabolism, inflammation, and insulin/IGF signaling
Publikováno v:
Journal of Alzheimer's disease : JAD. 17(3)
Nitrosamines mediate their mutagenic effects by causing DNA damage, oxidative stress, lipid peroxidation, and pro-inflammatory cytokine activation, which lead to increased cellular degeneration and death. However, the very same pathophysiological pro
Autor:
DeNucci, Sarah M.1,2, Ming Tong1,2, Longato, Lisa1,2, Lawton, Margot1,2, Setshedi, Mashiko1,2, Carlson, Rolf I.1,2, Wands, Jack R.1,2, de la Monte, Suzanne M.1,2 suzannedelamontemd@brown.edu
Publikováno v:
Gastroenterology Research & Practice. 2010, Vol. 2010, p1-16. 16p. 2 Color Photographs, 3 Charts, 6 Graphs.
Autor:
Tong, Ming1, Neusner, Alexander1, Longato, Lisa1, Lawton, Margot1, Wands, Jack R.1, De la Monte, Suzanne M.1 Suzanne DeLaMonte.MD@Brown.edu
Publikováno v:
Journal of Alzheimer's Disease. 2009, Vol. 17 Issue 4, p827-844. 12p. 3 Color Photographs, 1 Diagram, 12 Charts, 4 Graphs.
Autor:
De la Monte, Suzanne M.1 Suzanne_DeLaMonte_MD@Brown.edu, Neusner, Alexander1, Chu, Jennifer1, Lawton, Margot1
Publikováno v:
Journal of Alzheimer's Disease. 2009, Vol. 17 Issue 3, p519-529. 12p. 1 Diagram, 4 Graphs.