Cytokinetic Failure and Asynchronous Nuclear Division in BHK Cells Overexpressing a Truncated Protein-Tyrosine-Phosphatase

Autor: Cool, D. E., Andreassen, P. R., Tonks, N. K., Krebs, E. G., Fischer, E. H., Margolis, R. L.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1992 Jun . 89(12), 5422-5426.

Externí odkaz: https://www.jstor.org/stable/2359665

In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities

Autor: Debonis, S., Skoufias, D. A., Luc Lebeau, Lopez, R., Robin, G., Margolis, R. L., Wade, R. H., Kozielski, F.

Publikováno v: Scopus-Elsevier

Human Eg5, a member of the kinesin superfamily, plays a key role in mitosis, as it is required for the formation of a bipolar spindle. We describe here the first in vitro microtubule-activated ATPase-based assay for the identification of small-molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c21c5d50403d10326a16267a8631558
https://doi.org/10.1158/1535-7163.1079.3.9

Tubulin detyrosination is a frequent occurrence in breast cancers of poor prognosis

Autor: Mialhe, A., Lafanechère, L., Job, D., Treilleux, I., Peloux, N., Charles Dumontet, Brémond, A., Panh, M. -H, Payan, R., Wehland, J., Margolis, R. -L

Publikováno v: Cancer Research
Cancer Research, 2001, 61 (13), pp.5024-7
Scopus-Elsevier
Cancer Research, American Association for Cancer Research, 2001, 61 (13), pp.5024-7
ResearcherID

International audience; Tubulin, the dimeric subunit of microtubules, is a major cell protein that is centrally involved in cell division. Tubulin is subject to specific enzymatic posttranslational modifications including cyclic tyrosine removal and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9d4e45aa0ab03aec4893d10d3032fb32
https://pubmed.ncbi.nlm.nih.gov/11431336

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.